Basic Information:

  VIRBase ID:  

HHID00072232

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3140-3p:  MIMAT0015008          RTF2:  NM_001283037     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3140-3p	RTF2
miRBase Accession/Entrez ID	MIMAT0015008	51507
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C20orf43//CDAO5//HSPC164//RTFDC1//SHUJUN-3

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3140-3p	rs920076621 chr4:152489343    G/T rs973330937 chr4:152489342    T/C rs973330937 chr4:152489342    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RTF2	chr20:55078873(+) A-I      intronic chr20:55078913(+) A-I      intronic chr20:55076848(+) A-I      intronic chr20:55087185(+) A-I      intronic chr20:55090018(+) A-I      intronic chr20:55081898(+) A-I      intronic chr20:55080423(+) A-I      intronic chr20:55078987(+) A-I      intronic chr20:55078965(+) A-I      intronic chr20:55078904(+) A-I      intronic chr20:55078877(+) A-I      intronic chr20:55078870(+) A-I      intronic chr20:55078867(+) A-I      intronic chr20:55078778(+) A-I      intronic chr20:55084549(+) A-I      intronic chr20:55084610(+) A-I      intronic chr20:55084624(+) A-I      intronic chr20:55067552(+) A-I      intronic chr20:55076844(+) A-I      intronic chr20:55090024(+) A-I      intronic chr20:55090030(+) A-I      intronic chr20:55067556(+) A-I      intronic chr20:55067575(+) A-I      intronic chr20:55067978(+) A-I      intronic chr20:55076008(+) A-I      intronic chr20:55075861(+) A-I      intronic chr20:55075860(+) A-I      intronic chr20:55073444(+) A-I      intronic chr20:55073355(+) A-I      intronic chr20:55048837(+) A-I      intronic chr20:55052660(+) A-I      intronic chr20:55067308(+) A-I      intronic chr20:55081850(+) A-I      intronic chr20:55067354(+) A-I      intronic chr20:55067550(+) A-I      intronic chr20:55087183(+) A-I      intronic chr20:55087102(+) A-I      intronic chr20:55087100(+) A-I      intronic chr20:55087097(+) A-I      intronic chr20:55087006(+) A-I      intronic chr20:55084548(+) A-I      intronic chr20:55081891(+) A-I      intronic chr20:55081886(+) A-I      intronic chr20:55052625(+) A-I      intronic chr20:55052749(+) A-I      intronic chr20:55080360(+) A-I      intronic chr20:55064189(+) A-I      intronic chr20:55063352(+) A-I      intronic chr20:55080483(+) A-I      intronic chr20:55084402(+) A-I      intronic chr20:55081896(+) A-I      intronic chr20:55046573(+) A-I      intronic chr20:55065753(+) A-I      intronic chr20:55061625(+) A-I      intronic chr20:55065670(+) A-I      intronic chr20:55078887(+) A-I      intronic chr20:55067320(+) A-I      intronic chr20:55058599(+) A-I      intronic chr20:55053342(+) A-I      intronic chr20:55068070(+) A-I      intronic chr20:55081938(+) A-I      intronic chr20:55078949(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3140-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	RTF2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3140-3p
Interactor2: RTF2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.