Detail Information

Basic Information:


  VIRBase ID:  

HHID00072185

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-466:           EIF1AD:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-466 EIF1AD
miRBase
Accession/Entrez ID		 MIMAT0015002 84285
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - haponin//OBELIX

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-466
rs1368640537 chr3:31161720    G/A
rs1392123954 chr3:31161725    G/A
rs1436733428 chr3:31161724    C/CGTGTAT
rs1460320210 chr3:31161721    T/C
rs148367480 chr3:31161715    T/G
rs540140185 chr3:31161736    T/C
rs548026272 chr3:31161724    C/T
rs1044765198 chr3:31161730    T/C
rs1055171867 chr3:31161731    G/C
rs116476604 chr3:31161729    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR EIF1AD
chr11:65764712(-) A-I      3'UTR
chr11:65764735(-) A-I      3'UTR
chr11:65764711(-) A-I      3'UTR
chr11:65764698(-) A-I      3'UTR
chr11:65764686(-) A-I      3'UTR
chr11:65764715(-) A-I      3'UTR
chr11:65764507(-) A-I      3'UTR
chr11:65764470(-) A-I      3'UTR
chr11:65767359(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED EIF1AD
chr11:65765604(-) A-C exon 3'UTR    21725310

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase EIF1AD
chr11:65764591-65764592(-) m6A 3'UTR       24209618
chr11:65764678-65764679(-) m6A 3'UTR       24209618
chr11:65764825-65764826(-) m6A 3'UTR       27773535
chr11:65764848-65764849(-) m6A 3'UTR       27773535
chr11:65764854-65764855(-) m6A 3'UTR       27773535
chr11:65764937-65764938(-) m6A 3'UTR       27773535
chr11:65765000-65765001(-) m6A 3'UTR       27773535
chr11:65765047-65765048(-) m6A 3'UTR       27773535
chr11:65765058-65765059(-) m6A 3'UTR       27773535
chr11:65765103-65765104(-) m6A 3'UTR       24981863//27773535
chr11:65765131-65765132(-) m6A 3'UTR       24284625//24981863//27773535
chr11:65765157-65765158(-) m6A 3'UTR       24284625//24209618//24981863//27773535
chr11:65765174-65765175(-) m6A 3'UTR       24284625//24209618//24981863//27773535
chr11:65765355-65765356(-) m6A 3'UTR       24284625//24209618//24981863//27773535
chr11:65765374-65765375(-) m6A 3'UTR       24209618//24981863//27773535
chr11:65765614-65765615(-) m6A 3'UTR       27773535
chr11:65765821-65765822(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr11:65765842-65765843(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr11:65765918-65765919(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr11:65765944-65765945(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr11:65765966-65765967(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:65766008-65766009(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:65766035-65766036(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:65766059-65766060(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:65766067-65766068(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:65766117-65766118(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:65766124-65766125(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:65766198-65766199(-) m6A 3'UTR//CDS       24209618//27773535//27371828//27773536//22608085
chr11:65766209-65766210(-) m6A 3'UTR//CDS       24209618//27773535//27371828//27773536//22608085
chr11:65766823-65766824(-) m6A 3'UTR//CDS       24209618//27773535//27371828//27773536//22608085
chr11:65766837-65766838(-) m6A 3'UTR//CDS       27773535//27371828
chr11:65767070-65767071(-) m6A 3'UTR//CDS       27773535
chr11:65767142-65767143(-) m6A CDS       27773535
chr11:65767437-65767438(-) m6A exon//intron       27773535
chr11:65767460-65767461(-) m6A exon//intron       27773535
chr11:65767540-65767541(-) m6A CDS//exon//intron       -
chr11:65767592-65767593(-) m6A 5'UTR//CDS//exon       27773535
chr11:65767612-65767613(-) m6A 5'UTR//CDS//exon       27773535
chr11:65767622-65767623(-) m6A 5'UTR//CDS//exon       27773535
chr11:65767917-65767918(-) m6A 5'UTR//exon//intron       27773535//27371828
chr11:65767950-65767951(-) m6A 5'UTR//exon//intron       27773535//27371828
chr11:65767994-65767995(-) m6A 5'UTR//intron       27371828
chr11:65768013-65768014(-) m6A 5'UTR//intron       27371828
chr11:65768021-65768022(-) m6A 5'UTR//intron       27371828
chr11:65768052-65768053(-) m6A 5'UTR//intron       24981863//27371828
chr11:65768082-65768083(-) m6A 5'UTR//intron       24981863
chr11:65769546-65769547(-) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//26404942//27371828//27773536//22608085
chr11:65769555-65769556(-) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//26404942//27371828//27773536//22608085
chr11:65769562-65769563(-) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//26404942//27371828//27773536//22608085
chr11:65769572-65769573(-) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//26404942//27371828//27773536//22608085
chr11:65769598-65769599(-) m6A 5'UTR//exon       24284625//25456834//24981863//26404942//27371828//27773536//22608085
chr11:65769604-65769605(-) m6A 5'UTR//exon       24284625//25456834//24981863//26404942//27371828//27773536//22608085
chr11:65769638-65769639(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-466
Exosome Serum     18589210
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
EIF1AD
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-466
Interactor2: EIF1AD

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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