Basic Information:

  VIRBase ID:  

HHID00072182

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-466:  MIMAT0015002          PALS1:  NM_001256550     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-466	PALS1
miRBase Accession/Entrez ID	MIMAT0015002	64398
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	MPP5

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-466	rs1368640537 chr3:31161720    G/A rs1392123954 chr3:31161725    G/A rs1436733428 chr3:31161724    C/CGTGTAT rs1460320210 chr3:31161721    T/C rs148367480 chr3:31161715    T/G rs540140185 chr3:31161736    T/C rs548026272 chr3:31161724    C/T rs1044765198 chr3:31161730    T/C rs1055171867 chr3:31161731    G/C rs116476604 chr3:31161729    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PALS1	chr14:67753413(+) A-I      intronic chr14:67753416(+) A-I      intronic chr14:67753417(+) A-I      intronic chr14:67753515(+) A-I      intronic chr14:67753519(+) A-I      intronic chr14:67753555(+) A-I      intronic chr14:67753770(+) A-I      intronic chr14:67753773(+) A-I      intronic chr14:67763282(+) A-I      intronic chr14:67754926(+) A-I      intronic chr14:67763215(+) A-I      intronic chr14:67763219(+) A-I      intronic chr14:67714344(+) A-I      intronic chr14:67714394(+) A-I      intronic chr14:67763231(+) A-I      intronic chr14:67763249(+) A-I      intronic chr14:67763248(+) A-I      intronic chr14:67751198(+) A-I      intronic chr14:67734105(+) A-I      intronic chr14:67763240(+) A-I      intronic chr14:67763244(+) A-I      intronic chr14:67734101(+) A-I      intronic chr14:67788047(+) A-I      intronic chr14:67734076(+) A-I      intronic chr14:67751203(+) A-I      intronic chr14:67734080(+) A-I      intronic chr14:67751179(+) A-I      intronic chr14:67762087(+) A-I      intronic chr14:67722505(+) A-I      intronic chr14:67726209(+) A-I      intronic chr14:67754914(+) A-I      intronic chr14:67762126(+) A-I      intronic chr14:67754963(+) A-I      intronic chr14:67720371(+) A-I      intronic chr14:67762086(+) A-I      intronic chr14:67753529(+) A-I      intronic chr14:67751065(+) A-I      intronic chr14:67721710(+) A-I      intronic chr14:67719094(+) A-I      intronic chr14:67719073(+) A-I      intronic chr14:67767661(+) A-I      intronic chr14:67732427(+) A-I      intronic chr14:67721613(+) A-I      intronic chr14:67726254(+) A-I      intronic chr14:67732059(+) A-I      intronic chr14:67718064(+) A-I      intronic chr14:67722571(+) A-I      intronic chr14:67738668(+) A-I      intronic chr14:67762078(+) A-I      intronic chr14:67739588(+) A-I      intronic chr14:67721745(+) A-I      intronic chr14:67732453(+) A-I      intronic chr14:67732166(+) A-I      intronic chr14:67738681(+) A-I      intronic chr14:67719055(+) A-I      intronic chr14:67721800(+) A-I      intronic chr14:67751068(+) A-I      intronic chr14:67751629(+) A-I      intronic chr14:67732064(+) A-I      intronic chr14:67751059(+) A-I      intronic chr14:67762070(+) A-I      intronic chr14:67754847(+) A-I      intronic chr14:67721786(+) A-I      intronic chr14:67738695(+) A-I      intronic chr14:67755010(+) A-I      intronic chr14:67718055(+) A-I      intronic chr14:67753414(+) A-I      intronic chr14:67754991(+) A-I      intronic chr14:67721759(+) A-I      intronic chr14:67738677(+) A-I      intronic chr14:67719134(+) A-I      intronic chr14:67751651(+) A-I      intronic chr14:67714531(+) A-I      intronic chr14:67761636(+) A-I      intronic chr14:67761596(+) A-I      intronic chr14:67758001(+) A-I      intronic chr14:67754979(+) A-I      intronic chr14:67732454(+) A-I      intronic chr14:67721755(+) A-I      intronic chr14:67722587(+) A-I      intronic chr14:67753420(+) A-I      intronic chr14:67761531(+) A-I      intronic chr14:67761529(+) A-I      intronic chr14:67754828(+) A-I      intronic chr14:67761451(+) A-I      intronic chr14:67753411(+) A-I      intronic chr14:67751703(+) A-I      intronic chr14:67757435(+) A-I      intronic chr14:67723427(+) A-I      intronic chr14:67738602(+) A-I      intronic chr14:67719110(+) A-I      intronic chr14:67757422(+) A-I      intronic chr14:67726081(+) A-I      intronic chr14:67753408(+) A-I      intronic chr14:67726152(+) A-I      intronic chr14:67753503(+) A-I      intronic chr14:67726167(+) A-I      intronic chr14:67755038(+) A-I      intronic chr14:67754942(+) A-I      intronic chr14:67755033(+) A-I      intronic chr14:67753771(+) A-I      intronic chr14:67753476(+) A-I      intronic chr14:67753317(+) A-I      intronic chr14:67753495(+) A-I      intronic chr14:67743037(+) A-I      intronic chr14:67755060(+) A-I      intronic chr14:67782063(+) A-I      intronic chr14:67753315(+) A-I      intronic chr14:67723390(+) A-I      intronic chr14:67726421(+) A-I      intronic chr14:67739654(+) A-I      intronic chr14:67726372(+) A-I      intronic chr14:67751195(+) A-I      intronic chr14:67751200(+) A-I      intronic chr14:67714476(+) A-I      intronic chr14:67732092(+) A-I      intronic chr14:67725142(+) A-I      intronic chr14:67738729(+) A-I      intronic chr14:67723365(+) A-I      intronic chr14:67762164(+) A-I      intronic chr14:67738604(+) A-I      intronic chr14:67722456(+) A-I      intronic chr14:67752293(+) A-I      intronic chr14:67725265(+) A-I      intronic chr14:67754897(+) A-I      intronic chr14:67751062(+) A-I      intronic chr14:67753500(+) A-I      intronic chr14:67718976(+) A-I      intronic chr14:67718103(+) A-I      intronic chr14:67751086(+) A-I      intronic chr14:67754962(+) A-I      intronic chr14:67782591(+) A-I      intronic chr14:67720417(+) A-I      intronic chr14:67726445(+) A-I      intronic chr14:67733775(+) A-I      intronic chr14:67732523(+) A-I      intronic chr14:67732152(+) A-I      intronic chr14:67725725(+) A-I      intronic chr14:67751730(+) A-I      intronic chr14:67726163(+) A-I      intronic chr14:67751114(+) A-I      intronic chr14:67725325(+) A-I      intronic chr14:67715953(+) A-I      intronic chr14:67725336(+) A-I      intronic chr14:67733617(+) A-I      intronic chr14:67738526(+) A-I      intronic chr14:67722506(+) A-I      intronic chr14:67720380(+) A-I      intronic chr14:67753387(+) A-I      intronic chr14:67753777(+) A-I      intronic chr14:67726222(+) A-I      intronic chr14:67719093(+) A-I      intronic chr14:67726218(+) A-I      intronic chr14:67718241(+) A-I      intronic chr14:67726249(+) A-I      intronic chr14:67738667(+) A-I      intronic chr14:67753701(+) A-I      intronic chr14:67755061(+) A-I      intronic chr14:67715784(+) A-I      intronic chr14:67753464(+) A-I      intronic chr14:67732227(+) A-I      intronic chr14:67757168(+) A-I      intronic chr14:67753291(+) A-I      intronic chr14:67726373(+) A-I      intronic chr14:67751715(+) A-I      intronic chr14:67751189(+) A-I      intronic chr14:67725116(+) A-I      intronic chr14:67730714(+) A-I      intronic chr14:67753788(+) A-I      intronic chr14:67757155(+) A-I      intronic chr14:67732428(+) A-I      intronic chr14:67751105(+) A-I      intronic chr14:67723382(+) A-I      intronic chr14:67753318(+) A-I      intronic chr14:67757997(+) A-I      intronic chr14:67739665(+) A-I      intronic chr14:67752268(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-466	Exosome Serum     18589210 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	PALS1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-466
Interactor2: PALS1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.