Detail Information

Basic Information:


  VIRBase ID:  

HHID00072169

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-466:           MAGED2:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-466 MAGED2
miRBase
Accession/Entrez ID		 MIMAT0015002 10916
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - 11B6//BARTS5//BCG-1//BCG1//HCA10//MAGE-D2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-466
rs1368640537 chr3:31161720    G/A
rs1392123954 chr3:31161725    G/A
rs1436733428 chr3:31161724    C/CGTGTAT
rs1460320210 chr3:31161721    T/C
rs148367480 chr3:31161715    T/G
rs540140185 chr3:31161736    T/C
rs548026272 chr3:31161724    C/T
rs1044765198 chr3:31161730    T/C
rs1055171867 chr3:31161731    G/C
rs116476604 chr3:31161729    A/G

RNA Editing:


Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MAGED2
chrX:54842324(+) T-C intron -    21725310

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MAGED2
chrX:54834180-54834181(+) m6A 5'UTR       24284625//25456834//24981863
chrX:54834192-54834193(+) m6A 5'UTR//exon       24284625//25456834//24981863
chrX:54834218-54834219(+) m6A 5'UTR//exon       24284625//25456834//24981863
chrX:54834230-54834231(+) m6A 5'UTR//exon       24284625//25456834//24981863
chrX:54834775-54834776(+) m6A 5'UTR//intron       -
chrX:54835574-54835575(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863
chrX:54835645-54835646(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863
chrX:54835762-54835763(+) m6A 5'UTR//exon       24981863
chrX:54836173-54836174(+) m6A CDS//exon//intron       24981863
chrX:54836193-54836194(+) m6A CDS//exon//intron       24981863
chrX:54836232-54836233(+) m6A CDS//exon//intron       -
chrX:54837409-54837410(+) m6A CDS//exon//intron       24284625//25456834//24981863
chrX:54841865-54841866(+) m6A CDS       25456834//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-466
Exosome Serum     18589210
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
MAGED2
Chromatin HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-466
Interactor2: MAGED2

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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