Basic Information:

  VIRBase ID:  

HHID00072163

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-466:  MIMAT0015002          KIAA0232:  NM_001100590     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-466	KIAA0232
miRBase Accession/Entrez ID	MIMAT0015002	9778
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-466	rs1368640537 chr3:31161720    G/A rs1392123954 chr3:31161725    G/A rs1436733428 chr3:31161724    C/CGTGTAT rs1460320210 chr3:31161721    T/C rs148367480 chr3:31161715    T/G rs540140185 chr3:31161736    T/C rs548026272 chr3:31161724    C/T rs1044765198 chr3:31161730    T/C rs1055171867 chr3:31161731    G/C rs116476604 chr3:31161729    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	KIAA0232	chr4:6802180(+) A-I      intronic chr4:6802189(+) A-I      intronic chr4:6802238(+) A-I      intronic chr4:6827746(+) A-I      intronic chr4:6802248(+) A-I      intronic chr4:6802249(+) A-I      intronic chr4:6802250(+) A-I      intronic chr4:6800499(+) A-I      intronic chr4:6867126(+) A-I      intronic chr4:6802251(+) A-I      intronic chr4:6827780(+) A-I      intronic chr4:6840057(+) A-I      intronic chr4:6840105(+) A-I      intronic chr4:6840125(+) A-I      intronic chr4:6802287(+) A-I      intronic chr4:6791645(+) A-I      intronic chr4:6802288(+) A-I      intronic chr4:6802363(+) A-I      intronic chr4:6803138(+) A-I      intronic chr4:6803161(+) A-I      intronic chr4:6803226(+) A-I      intronic chr4:6845350(+) A-I      intronic chr4:6803296(+) A-I      intronic chr4:6803346(+) A-I      intronic chr4:6840646(+) A-I      intronic chr4:6840654(+) A-I      intronic chr4:6813270(+) A-I      intronic chr4:6813287(+) A-I      intronic chr4:6819966(+) A-I      intronic chr4:6819967(+) A-I      intronic chr4:6791140(+) A-I      intronic chr4:6791482(+) A-I      intronic chr4:6791591(+) A-I      intronic chr4:6866400(+) A-I      intronic chr4:6866378(+) A-I      intronic chr4:6866372(+) A-I      intronic chr4:6860731(+) A-I      intronic chr4:6860718(+) A-I      intronic chr4:6860714(+) A-I      intronic chr4:6867096(+) A-I      intronic chr4:6866306(+) A-I      intronic chr4:6791625(+) A-I      intronic chr4:6791635(+) A-I      intronic chr4:6791649(+) A-I      intronic chr4:6866301(+) A-I      intronic chr4:6866256(+) A-I      intronic chr4:6866241(+) A-I      intronic chr4:6840754(+) A-I      intronic chr4:6857050(+) A-I      intronic chr4:6857029(+) A-I      intronic chr4:6856946(+) A-I      intronic chr4:6856945(+) A-I      intronic chr4:6856912(+) A-I      intronic chr4:6802175(+) A-I      intronic chr4:6851183(+) A-I      intronic chr4:6851178(+) A-I      intronic chr4:6840755(+) A-I      intronic chr4:6840764(+) A-I      intronic chr4:6791592(+) A-I      intronic chr4:6791641(+) A-I      intronic chr4:6860710(+) A-I      intronic chr4:6791602(+) A-I      intronic chr4:6860696(+) A-I      intronic chr4:6791595(+) A-I      intronic chr4:6791593(+) A-I      intronic chr4:6819981(+) A-I      intronic chr4:6820045(+) A-I      intronic chr4:6820048(+) A-I      intronic chr4:6840765(+) A-I      intronic chr4:6840778(+) A-I      intronic chr4:6840785(+) A-I      intronic chr4:6842476(+) A-I      intronic chr4:6844382(+) A-I      intronic chr4:6791658(+) A-I      intronic chr4:6791662(+) A-I      intronic chr4:6802247(+) A-I      intronic chr4:6840081(+) A-I      intronic chr4:6791652(+) A-I      intronic chr4:6867208(+) A-I      intronic chr4:6788130(+) A-I      intronic chr4:6788282(+) A-I      intronic chr4:6790815(+) A-I      intronic chr4:6844383(+) A-I      intronic chr4:6793114(+) A-I      intronic chr4:6793197(+) A-I      intronic chr4:6793205(+) A-I      intronic chr4:6790854(+) A-I      intronic chr4:6793317(+) A-I      intronic chr4:6800302(+) A-I      intronic chr4:6801522(+) A-I      intronic chr4:6801596(+) A-I      intronic chr4:6801602(+) A-I      intronic chr4:6801619(+) A-I      intronic chr4:6801884(+) A-I      intronic chr4:6801911(+) A-I      intronic chr4:6801924(+) A-I      intronic chr4:6802154(+) A-I      intronic chr4:6840116(+) A-I      intronic chr4:6844393(+) A-I      intronic chr4:6845286(+) A-I      intronic chr4:6845300(+) A-I      intronic chr4:6845339(+) A-I      intronic chr4:6845332(+) A-I      intronic chr4:6845335(+) A-I      intronic chr4:6851168(+) A-I      intronic chr4:6846320(+) A-I      intronic chr4:6846280(+) A-I      intronic chr4:6845806(+) A-I      intronic chr4:6845784(+) A-I      intronic chr4:6845766(+) A-I      intronic chr4:6867271(+) A-I      intronic chr4:6867250(+) A-I      intronic chr4:6867249(+) A-I      intronic chr4:6840082(+) A-I      intronic chr4:6845849(+) A-I      intronic chr4:6808837(+) A-I      intronic chr4:6840774(+) A-I      intronic chr4:6835207(+) A-I      intronic chr4:6835277(+) A-I      intronic chr4:6788747(+) A-I      intronic chr4:6804643(+) A-I      intronic chr4:6788858(+) A-I      intronic chr4:6802261(+) A-I      intronic chr4:6801636(+) A-I      intronic chr4:6830021(+) A-I      intronic chr4:6788868(+) A-I      intronic chr4:6819037(+) A-I      intronic chr4:6790981(+) A-I      intronic chr4:6803201(+) A-I      intronic chr4:6820052(+) A-I      intronic chr4:6872275(+) A-I      intronic chr4:6796974(+) A-I      intronic chr4:6790827(+) A-I      intronic chr4:6790724(+) A-I      intronic chr4:6840028(+) A-I      intronic chr4:6835844(+) A-I      intronic chr4:6867256(+) A-I      intronic chr4:6796817(+) A-I      intronic chr4:6800465(+) A-I      intronic chr4:6788169(+) A-I      intronic chr4:6835206(+) A-I      intronic chr4:6846220(+) A-I      intronic chr4:6802050(+) A-I      intronic chr4:6808812(+) A-I      intronic chr4:6788219(+) A-I      intronic chr4:6856998(+) A-I      intronic chr4:6792827(+) A-I      intronic chr4:6819149(+) A-I      intronic chr4:6788104(+) A-I      intronic chr4:6845295(+) A-I      intronic chr4:6845468(+) A-I      intronic chr4:6788854(+) A-I      intronic chr4:6802360(+) A-I      intronic chr4:6790972(+) A-I      intronic chr4:6819083(+) A-I      intronic chr4:6866202(+) A-I      intronic chr4:6840136(+) A-I      intronic chr4:6835236(+) A-I      intronic chr4:6790837(+) A-I      intronic chr4:6867144(+) A-I      intronic chr4:6819910(+) A-I      intronic chr4:6802323(+) A-I      intronic chr4:6791478(+) A-I      intronic chr4:6800434(+) A-I      intronic chr4:6808283(+) A-I      intronic chr4:6788787(+) A-I      intronic chr4:6867202(+) A-I      intronic chr4:6867225(+) A-I      intronic chr4:6808301(+) A-I      intronic chr4:6791596(+) A-I      intronic chr4:6866399(+) A-I      intronic chr4:6791054(+) A-I      intronic chr4:6799705(+) A-I      intronic chr4:6867263(+) A-I      intronic chr4:6788297(+) A-I      intronic chr4:6792291(+) A-I      intronic chr4:6846224(+) A-I      intronic chr4:6800380(+) A-I      intronic chr4:6788820(+) A-I      intronic chr4:6801631(+) A-I      intronic chr4:6788655(+) A-I      intronic chr4:6791496(+) A-I      intronic chr4:6799372(+) A-I      intronic chr4:6802229(+) A-I      intronic chr4:6845234(+) A-I      intronic chr4:6791613(+) A-I      intronic chr4:6801918(+) A-I      intronic chr4:6835201(+) A-I      intronic chr4:6872274(+) A-I      intronic chr4:6802293(+) A-I      intronic chr4:6847112(+) A-I      intronic chr4:6800371(+) A-I      intronic chr4:6793239(+) A-I      intronic chr4:6799638(+) A-I      intronic chr4:6851416(+) A-I      intronic chr4:6846383(+) A-I      intronic chr4:6788175(+) A-I      intronic chr4:6790905(+) A-I      intronic chr4:6790959(+) A-I      intronic chr4:6799268(+) A-I      intronic chr4:6793149(+) A-I      intronic chr4:6788707(+) A-I      intronic chr4:6802333(+) A-I      intronic chr4:6872418(+) A-I      intronic chr4:6873110(+) A-I      intronic chr4:6846437(+) A-I      intronic chr4:6788654(+) A-I      intronic chr4:6866398(+) A-I      intronic chr4:6866304(+) A-I      intronic chr4:6791606(+) A-I      intronic chr4:6867120(+) A-I      intronic chr4:6793101(+) A-I      intronic chr4:6842475(+) A-I      intronic chr4:6866362(+) A-I      intronic chr4:6788829(+) A-I      intronic chr4:6820017(+) A-I      intronic chr4:6800466(+) A-I      intronic chr4:6788123(+) A-I      intronic chr4:6793330(+) A-I      intronic chr4:6867050(+) A-I      intronic chr4:6804805(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	KIAA0232	chr4:6808895(+) A-I intron -    21960545 chr4:6788104(+) A-G intron -    22484847 chr4:6788123(+) A-G intron -    22484847 chr4:6788169(+) A-G intron -    22484847 chr4:6788175(+) A-G intron -    22484847 chr4:6788297(+) A-G intron -    22484847 chr4:6788699(+) A-G intron -    22484847 chr4:6788707(+) A-G intron -    22484847 chr4:6790724(+) A-G intron -    22484847 chr4:6790827(+) A-G intron -    22484847 chr4:6790837(+) A-G intron -    22484847 chr4:6790905(+) A-G intron -    22484847 chr4:6790972(+) A-G intron -    22484847 chr4:6791596(+) A-G intron -    22484847 chr4:6791613(+) A-G intron -    22484847 chr4:6799273(+) G-A intron -    22484847 chr4:6800420(+) A-G intron -    22484847 chr4:6800465(+) A-G intron -    22484847 chr4:6800466(+) A-G intron -    22484847 chr4:6802329(+) A-G intron -    22484847 chr4:6818228(+) A-C intron -    22484847 chr4:6820052(+) A-G intron -    22484847 chr4:6839947(+) A-G intron -    22484847 chr4:6840028(+) A-G intron -    22484847 chr4:6840136(+) A-G intron -    22484847 chr4:6842475(+) A-G intron -    22484847 chr4:6845223(+) A-G intron -    22484847 chr4:6845234(+) A-G intron -    22484847 chr4:6845874(+) A-G intron -    22484847 chr4:6846224(+) A-G intron -    22484847 chr4:6867050(+) A-G intron -    22484847 chr4:6867120(+) A-G intron -    22484847 chr4:6867144(+) A-G intron -    22484847 chr4:6867256(+) A-G intron -    22484847 chr4:6872252(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	KIAA0232	chr4:6806282-6806283(+) m6A 5'UTR//intron       24209618 chr4:6862660-6862661(+) m6A CDS//exon       24284625 chr4:6862695-6862696(+) m6A CDS       24284625//24981863 chr4:6862779-6862780(+) m6A CDS       24284625//24981863//27773535//22608085 chr4:6862847-6862848(+) m6A CDS       24981863//27773535//22608085 chr4:6862878-6862879(+) m6A CDS       24981863//27773535//22608085 chr4:6862942-6862943(+) m6A CDS       24981863//22608085 chr4:6863056-6863057(+) m6A CDS       24284625//24981863//27773535//22608085 chr4:6863079-6863080(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr4:6863142-6863143(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:6863188-6863189(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:6863212-6863213(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:6863262-6863263(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:6863286-6863287(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr4:6863365-6863366(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6863372-6863373(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6863385-6863386(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6863480-6863481(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6863564-6863565(+) m6A CDS       24284625//26404942//22608085 chr4:6863589-6863590(+) m6A CDS       24284625//22608085 chr4:6863684-6863685(+) m6A CDS       24284625//24981863//22608085 chr4:6863739-6863740(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6863810-6863811(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6863856-6863857(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr4:6863934-6863935(+) m6A CDS       24284625//24981863//22608085 chr4:6863947-6863948(+) m6A CDS       24284625//24981863//22608085 chr4:6863964-6863965(+) m6A CDS       24284625//22608085 chr4:6864042-6864043(+) m6A CDS       24284625//22608085 chr4:6864104-6864105(+) m6A CDS       24284625//24981863//22608085 chr4:6864158-6864159(+) m6A CDS       24284625//24981863//26404942//22608085 chr4:6864182-6864183(+) m6A CDS       24284625//24981863//22608085 chr4:6864211-6864212(+) m6A CDS       24284625//24981863//22608085 chr4:6864236-6864237(+) m6A CDS       24981863//22608085 chr4:6864266-6864267(+) m6A CDS       24981863//22608085 chr4:6864276-6864277(+) m6A CDS       24981863//22608085 chr4:6864284-6864285(+) m6A CDS       24981863//22608085 chr4:6864379-6864380(+) m6A CDS       24981863//22608085 chr4:6864404-6864405(+) m6A CDS       24981863//22608085 chr4:6864417-6864418(+) m6A CDS       24284625//24981863//22608085 chr4:6864425-6864426(+) m6A CDS       24284625//24981863//22608085 chr4:6864461-6864462(+) m6A CDS       24284625//24981863//27773535//22608085 chr4:6864469-6864470(+) m6A CDS       24284625//24981863//27773535//22608085 chr4:6864499-6864500(+) m6A CDS       24284625//24981863//27773535//22608085 chr4:6864506-6864507(+) m6A CDS       24284625//24981863//27773535//22608085 chr4:6864513-6864514(+) m6A CDS       24284625//24981863//27773535//22608085 chr4:6864527-6864528(+) m6A CDS       24284625//24981863//27773535//22608085 chr4:6864588-6864589(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr4:6864596-6864597(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr4:6864609-6864610(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr4:6864644-6864645(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr4:6864709-6864710(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr4:6864716-6864717(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr4:6864772-6864773(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr4:6864856-6864857(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6864885-6864886(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6864916-6864917(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:6864923-6864924(+) m6A CDS       24981863//22608085 chr4:6865047-6865048(+) m6A CDS       22608085 chr4:6865081-6865082(+) m6A CDS       22608085 chr4:6865099-6865100(+) m6A CDS       22608085 chr4:6865167-6865168(+) m6A CDS       24284625//24981863//22608085 chr4:6865210-6865211(+) m6A CDS       24284625//24981863//22608085 chr4:6865285-6865286(+) m6A CDS       24284625//24981863//22608085 chr4:6865321-6865322(+) m6A CDS       24284625//24981863//22608085 chr4:6865350-6865351(+) m6A CDS       24284625//25456834//24981863//22608085 chr4:6865391-6865392(+) m6A CDS       24284625//25456834//24981863//22608085 chr4:6865424-6865425(+) m6A CDS       24284625//25456834//24981863//22608085 chr4:6865453-6865454(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr4:6865564-6865565(+) m6A CDS       24284625//24981863//22608085 chr4:6865676-6865677(+) m6A CDS       24981863//22608085 chr4:6882621-6882622(+) m6A CDS       24981863 chr4:6882681-6882682(+) m6A CDS       24981863 chr4:6882693-6882694(+) m6A 3'UTR       24981863 chr4:6882758-6882759(+) m6A 3'UTR       24981863 chr4:6882773-6882774(+) m6A 3'UTR       24981863 chr4:6883080-6883081(+) m6A 3'UTR       24284625//24981863//22608085 chr4:6883118-6883119(+) m6A 3'UTR       24284625//24981863//22608085 chr4:6883237-6883238(+) m6A 3'UTR       24981863 chr4:6883260-6883261(+) m6A 3'UTR       24981863 chr4:6883389-6883390(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-466	Exosome Serum     18589210 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	KIAA0232	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-466
Interactor2: KIAA0232

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.