Detail Information

Basic Information:


  VIRBase ID:  

HHID00072147

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-466:           PCBP1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-466 PCBP1
miRBase
Accession/Entrez ID		 MIMAT0015002 5093
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HEL-S-85//hnRNP-E1//hnRNP-X//HNRPE1//HNRPX

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-466
rs1368640537 chr3:31161720    G/A
rs1392123954 chr3:31161725    G/A
rs1436733428 chr3:31161724    C/CGTGTAT
rs1460320210 chr3:31161721    T/C
rs148367480 chr3:31161715    T/G
rs540140185 chr3:31161736    T/C
rs548026272 chr3:31161724    C/T
rs1044765198 chr3:31161730    T/C
rs1055171867 chr3:31161731    G/C
rs116476604 chr3:31161729    A/G

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PCBP1
chr2:70314610-70314611(+) m6A 5'UTR       24209618//24981863
chr2:70314824-70314825(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr2:70314901-70314902(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr2:70315238-70315239(+) Gm CDS       -
chr2:70315522-70315523(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr2:70315552-70315553(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr2:70315590-70315591(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr2:70315603-70315604(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr2:70315637-70315638(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr2:70315712-70315713(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr2:70315723-70315724(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr2:70315947-70315948(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-466
Exosome Serum     18589210
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
PCBP1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-466
Interactor2: PCBP1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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