Basic Information:

  VIRBase ID:  

HHID00072146

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-466:  MIMAT0015002          NAB2:  NM_001330305     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-466	NAB2
miRBase Accession/Entrez ID	MIMAT0015002	4665
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	MADER

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-466	rs1368640537 chr3:31161720    G/A rs1392123954 chr3:31161725    G/A rs1436733428 chr3:31161724    C/CGTGTAT rs1460320210 chr3:31161721    T/C rs148367480 chr3:31161715    T/G rs540140185 chr3:31161736    T/C rs548026272 chr3:31161724    C/T rs1044765198 chr3:31161730    T/C rs1055171867 chr3:31161731    G/C rs116476604 chr3:31161729    A/G

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NAB2	chr12:57482898-57482899(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//27371828 chr12:57482941-57482942(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//27371828 chr12:57482952-57482953(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//27371828//27773536 chr12:57482962-57482963(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//27371828//27773536 chr12:57483103-57483104(+) m6A CDS//exon       24284625//24209618 chr12:57483117-57483118(+) m6A CDS//exon       24284625//24209618 chr12:57483131-57483132(+) m6A CDS//exon       24284625//24209618 chr12:57485001-57485002(+) m6A CDS//intron       24284625//24209618 chr12:57485220-57485221(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:57485318-57485319(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr12:57485351-57485352(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr12:57485365-57485366(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr12:57485481-57485482(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr12:57485511-57485512(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr12:57485527-57485528(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr12:57486714-57486715(+) m6A CDS//exon       - chr12:57486744-57486745(+) m6A CDS//exon       24284625 chr12:57486853-57486854(+) m6A CDS//exon       24284625 chr12:57486933-57486934(+) m6A CDS       24284625 chr12:57486967-57486968(+) m6A CDS       24284625 chr12:57487284-57487285(+) m6A CDS//intron       24284625 chr12:57488415-57488416(+) m6A CDS       24284625 chr12:57488434-57488435(+) m6A CDS       24284625 chr12:57488511-57488512(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr12:57488525-57488526(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr12:57488532-57488533(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr12:57488539-57488540(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr12:57488556-57488557(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr12:57488648-57488649(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:57488692-57488693(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:57488745-57488746(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:57488836-57488837(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:57488847-57488848(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:57488864-57488865(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:57488926-57488927(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr12:57488933-57488934(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr12:57489125-57489126(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-466	Exosome Serum     18589210 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	NAB2	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-466
Interactor2: NAB2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.