Basic Information:

  VIRBase ID:  

HHID00072054

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:  MIMAT0014983          TIGAR:  NM_020375     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3121-3p	TIGAR
miRBase Accession/Entrez ID	MIMAT0014983	57103
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C12orf5//FR2BP

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3121-3p	rs1006143795 chr1:180438334    T/C rs778817728 chr1:180438323    T/C rs887772082 chr1:180438327    C/T rs911596096 chr1:180438331    G/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TIGAR	chr12:4467455(+) A-I      3'UTR chr12:4467456(+) A-I      3'UTR chr12:4464159(+) A-I      3'UTR chr12:4463997(+) A-I      3'UTR chr12:4467385(+) A-I      3'UTR chr12:4467403(+) A-I      3'UTR chr12:4467411(+) A-I      3'UTR chr12:4444573(+) A-I      intronic chr12:4444614(+) A-I      intronic chr12:4457181(+) A-I      intronic chr12:4457092(+) A-I      intronic chr12:4447221(+) A-I      intronic chr12:4446432(+) A-I      intronic chr12:4437414(+) A-I      intronic chr12:4437034(+) A-I      intronic chr12:4437017(+) A-I      intronic chr12:4458835(+) A-I      intronic chr12:4436981(+) A-I      intronic chr12:4436951(+) A-I      intronic chr12:4457191(+) A-I      intronic chr12:4458648(+) A-I      intronic chr12:4458653(+) A-I      intronic chr12:4458688(+) A-I      intronic chr12:4447138(+) A-I      intronic chr12:4447095(+) A-I      intronic chr12:4446487(+) A-I      intronic chr12:4446437(+) A-I      intronic chr12:4436973(+) A-I      intronic chr12:4447175(+) A-I      intronic chr12:4458603(+) A-I      intronic chr12:4437458(+) A-I      intronic chr12:4432248(+) A-I      intronic chr12:4436319(+) A-I      intronic chr12:4457155(+) A-I      intronic chr12:4438605(+) A-I      intronic chr12:4457151(+) A-I      intronic chr12:4446546(+) A-I      intronic chr12:4459956(+) A-I      intronic chr12:4436425(+) A-I      intronic chr12:4447146(+) A-I      intronic chr12:4446450(+) A-I      intronic chr12:4447154(+) A-I      intronic chr12:4457077(+) A-I      intronic chr12:4447150(+) A-I      intronic chr12:4436410(+) A-I      intronic chr12:4447144(+) A-I      intronic chr12:4447141(+) A-I      intronic chr12:4446471(+) A-I      intronic chr12:4457120(+) A-I      intronic chr12:4446515(+) A-I      intronic chr12:4457147(+) A-I      intronic chr12:4462791(+) A-I      3'UTR chr12:4463972(+) A-I      3'UTR chr12:4462879(+) A-I      3'UTR chr12:4464001(+) A-I      3'UTR chr12:4462975(+) A-I      3'UTR chr12:4467377(+) A-I      3'UTR chr12:4464180(+) A-I      3'UTR chr12:4464177(+) A-I      3'UTR chr12:4464037(+) A-I      3'UTR chr12:4464027(+) A-I      3'UTR chr12:4464015(+) A-I      3'UTR chr12:4463978(+) A-I      3'UTR chr12:4463977(+) A-I      3'UTR chr12:4462921(+) A-I      3'UTR chr12:4462906(+) A-I      3'UTR chr12:4462748(+) A-I      3'UTR chr12:4462731(+) A-I      3'UTR chr12:4464077(+) A-I      3'UTR chr12:4446413(+) A-I      intronic chr12:4457217(+) A-I      intronic chr12:4447064(+) A-I      intronic chr12:4447137(+) A-I      intronic chr12:4457070(+) A-I      intronic chr12:4458687(+) A-I      intronic chr12:4436478(+) A-I      intronic chr12:4446554(+) A-I      intronic chr12:4434849(+) A-I      intronic chr12:4436303(+) A-I      intronic chr12:4436306(+) A-I      intronic chr12:4436934(+) A-I      intronic chr12:4447132(+) A-I      intronic chr12:4457045(+) A-I      intronic chr12:4458723(+) A-I      intronic chr12:4437541(+) A-I      intronic chr12:4457148(+) A-I      intronic chr12:4436454(+) A-I      intronic chr12:4437031(+) A-I      intronic chr12:4434898(+) A-I      intronic chr12:4432370(+) A-I      intronic chr12:4437419(+) A-I      intronic chr12:4436520(+) A-I      intronic chr12:4443401(+) A-I      intronic chr12:4443550(+) A-I      intronic chr12:4457150(+) A-I      intronic chr12:4436413(+) A-I      intronic chr12:4432417(+) A-I      intronic chr12:4443570(+) A-I      intronic chr12:4432369(+) A-I      intronic chr12:4447139(+) A-I      intronic chr12:4446560(+) A-I      intronic chr12:4432321(+) A-I      intronic chr12:4432416(+) A-I      intronic chr12:4436495(+) A-I      intronic chr12:4436455(+) A-I      intronic chr12:4436317(+) A-I      intronic chr12:4446407(+) A-I      intronic chr12:4432200(+) A-I      intronic chr12:4447023(+) A-I      intronic chr12:4447147(+) A-I      intronic chr12:4431343(+) A-I      intronic chr12:4436913(+) A-I      intronic chr12:4446493(+) A-I      intronic chr12:4446578(+) A-I      intronic chr12:4443384(+) A-I      intronic chr12:4436428(+) A-I      intronic chr12:4457030(+) A-I      intronic chr12:4444603(+) A-I      intronic chr12:4432342(+) A-I      intronic chr12:4438679(+) A-I      intronic chr12:4457046(+) A-I      intronic chr12:4437036(+) A-I      intronic chr12:4436933(+) A-I      intronic chr12:4444641(+) A-I      intronic chr12:4432285(+) A-I      intronic chr12:4447068(+) A-I      intronic chr12:4462818(+) A-I      3'UTR chr12:4463954(+) A-I      3'UTR chr12:4462800(+) A-I      3'UTR chr12:4463962(+) A-I      3'UTR chr12:4467331(+) A-I      3'UTR chr12:4467354(+) A-I      3'UTR chr12:4464140(+) A-I      3'UTR chr12:4462837(+) A-I      3'UTR chr12:4467149(+) A-I      3'UTR chr12:4463998(+) A-I      3'UTR chr12:4462880(+) A-I      3'UTR chr12:4467037(+) A-I      3'UTR chr12:4464080(+) A-I      3'UTR chr12:4467386(+) A-I      3'UTR chr12:4467401(+) A-I      3'UTR chr12:4462866(+) A-I      3'UTR

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TIGAR	chr12:4430435-4430436(+) m6A 5'UTR//intron       24284625//24981863 chr12:4433890-4433891(+) m6A exon//intron       24981863 chr12:4440452-4440453(+) m6A 5'UTR//CDS//exon       24981863 chr12:4459049-4459050(+) m6A CDS//exon       24981863 chr12:4460538-4460539(+) m6A CDS//exon       24981863//22608085 chr12:4461444-4461445(+) m6A CDS//exon       24981863//22608085 chr12:4461496-4461497(+) m6A CDS//exon       24981863//22608085 chr12:4461533-4461534(+) m6A CDS       24981863//22608085 chr12:4461591-4461592(+) m6A CDS       24284625//24981863//22608085 chr12:4461718-4461719(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr12:4461765-4461766(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:4461790-4461791(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:4461816-4461817(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr12:4461838-4461839(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr12:4461848-4461849(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr12:4461952-4461953(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr12:4461984-4461985(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr12:4462000-4462001(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr12:4462010-4462011(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr12:4462119-4462120(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3121-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	TIGAR	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3121-3p
Interactor2: TIGAR

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.