Basic Information:

  VIRBase ID:  

HHID00072052

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:  MIMAT0014983          FAM214A:  NM_001385015     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3121-3p	FAM214A
miRBase Accession/Entrez ID	MIMAT0014983	56204
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	KIAA1370

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3121-3p	rs1006143795 chr1:180438334    T/C rs778817728 chr1:180438323    T/C rs887772082 chr1:180438327    C/T rs911596096 chr1:180438331    G/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FAM214A	chr15:52904905(-) A-I      intronic chr15:52904921(-) A-I      intronic chr15:52904875(-) A-I      intronic chr15:52904881(-) A-I      intronic chr15:52904878(-) A-I      intronic chr15:52885230(-) A-I      intronic chr15:52885218(-) A-I      intronic chr15:52926367(-) A-I      intronic chr15:52890158(-) A-I      intronic chr15:52910960(-) A-I      intronic chr15:52912006(-) A-I      intronic chr15:52935713(-) A-I      intronic chr15:52911845(-) A-I      intronic chr15:52904383(-) A-I      intronic chr15:52904424(-) A-I      intronic chr15:52932571(-) A-I      intronic chr15:52961312(-) A-I      intronic chr15:52904756(-) A-I      intronic chr15:52904787(-) A-I      intronic chr15:52927655(-) A-I      intronic chr15:52961352(-) A-I      intronic chr15:52924194(-) A-I      intronic chr15:52904871(-) A-I      intronic chr15:52961307(-) A-I      intronic chr15:52904895(-) A-I      intronic chr15:52904903(-) A-I      intronic chr15:52961347(-) A-I      intronic chr15:52904929(-) A-I      intronic chr15:52927078(-) A-I      intronic chr15:52950959(-) A-I      intronic chr15:52937453(-) A-I      intronic chr15:52937560(-) A-I      intronic chr15:52935092(-) A-I      intronic chr15:52905441(-) A-I      intronic chr15:52905494(-) A-I      intronic chr15:52905516(-) A-I      intronic chr15:52932656(-) A-I      intronic chr15:52888259(-) A-I      intronic chr15:52926408(-) A-I      intronic chr15:52917249(-) A-I      intronic chr15:52906497(-) A-I      intronic chr15:52926907(-) A-I      intronic chr15:52956022(-) A-I      intronic chr15:52926963(-) A-I      intronic chr15:52932536(-) A-I      intronic chr15:52906928(-) A-I      intronic chr15:52882152(-) A-I      intronic chr15:52908746(-) A-I      intronic chr15:52908759(-) A-I      intronic chr15:52926520(-) A-I      intronic chr15:52961279(-) A-I      intronic chr15:52961391(-) A-I      intronic chr15:52961374(-) A-I      intronic chr15:52926413(-) A-I      intronic chr15:52961199(-) A-I      intronic chr15:52932161(-) A-I      intronic chr15:52904839(-) A-I      intronic chr15:52905447(-) A-I      intronic chr15:52961163(-) A-I      intronic chr15:52927022(-) A-I      intronic chr15:52910312(-) A-I      intronic chr15:52880774(-) A-I      intronic chr15:52957083(-) A-I      intronic chr15:52957052(-) A-I      intronic chr15:52957013(-) A-I      intronic chr15:52910344(-) A-I      intronic chr15:52890155(-) A-I      intronic chr15:52961252(-) A-I      intronic chr15:52956073(-) A-I      intronic chr15:52955939(-) A-I      intronic chr15:52954818(-) A-I      intronic chr15:52954800(-) A-I      intronic chr15:52953102(-) A-I      intronic chr15:52955957(-) A-I      intronic chr15:52910347(-) A-I      intronic chr15:52904955(-) A-I      intronic chr15:52932160(-) A-I      intronic chr15:52910360(-) A-I      intronic chr15:52950989(-) A-I      intronic chr15:52932115(-) A-I      intronic chr15:52937511(-) A-I      intronic chr15:52882186(-) A-I      intronic chr15:52937508(-) A-I      intronic chr15:52910374(-) A-I      intronic chr15:52883655(-) A-I      intronic chr15:52937444(-) A-I      intronic chr15:52936394(-) A-I      intronic chr15:52936320(-) A-I      intronic chr15:52957053(-) A-I      intronic chr15:52961355(-) A-I      intronic chr15:52953124(-) A-I      intronic chr15:52905559(-) A-I      intronic chr15:52936001(-) A-I      intronic chr15:52885178(-) A-I      intronic chr15:52905561(-) A-I      intronic chr15:52910384(-) A-I      intronic chr15:52880703(-) A-I      intronic chr15:52927049(-) A-I      intronic chr15:52932104(-) A-I      intronic chr15:52904834(-) A-I      intronic chr15:52932086(-) A-I      intronic chr15:52885260(-) A-I      intronic chr15:52961175(-) A-I      intronic chr15:52953123(-) A-I      intronic chr15:52961294(-) A-I      intronic chr15:52935999(-) A-I      intronic chr15:52932641(-) A-I      intronic chr15:52932076(-) A-I      intronic chr15:52882123(-) A-I      intronic chr15:52961243(-) A-I      intronic chr15:52930674(-) A-I      intronic chr15:52937536(-) A-I      intronic chr15:52927861(-) A-I      intronic chr15:52905477(-) A-I      intronic chr15:52905378(-) A-I      intronic chr15:52935097(-) A-I      intronic chr15:52926479(-) A-I      intronic chr15:52927672(-) A-I      intronic chr15:52904364(-) A-I      intronic chr15:52935998(-) A-I      intronic chr15:52935137(-) A-I      intronic chr15:52926385(-) A-I      intronic chr15:52904937(-) A-I      intronic chr15:52927887(-) A-I      intronic chr15:52935613(-) A-I      intronic chr15:52882053(-) A-I      intronic chr15:52885234(-) A-I      intronic chr15:52882025(-) A-I      intronic chr15:52882090(-) A-I      intronic chr15:52882106(-) A-I      intronic chr15:52885101(-) A-I      intronic chr15:52885123(-) A-I      intronic chr15:52885232(-) A-I      intronic chr15:52906498(-) A-I      intronic chr15:52882264(-) A-I      intronic chr15:52926488(-) A-I      intronic chr15:52932175(-) A-I      intronic chr15:52914171(-) A-I      intronic chr15:52882156(-) A-I      intronic chr15:52926978(-) A-I      intronic chr15:52885233(-) A-I      intronic chr15:52935644(-) A-I      intronic chr15:52883630(-) A-I      intronic chr15:52885193(-) A-I      intronic chr15:52937373(-) A-I      intronic chr15:52904934(-) A-I      intronic chr15:52885088(-) A-I      intronic chr15:52885310(-) A-I      intronic chr15:52882167(-) A-I      intronic chr15:52888195(-) A-I      intronic chr15:52954314(-) A-I      intronic chr15:52935759(-) A-I      intronic chr15:52961238(-) A-I      intronic chr15:52957011(-) A-I      intronic chr15:52883599(-) A-I      intronic chr15:52880800(-) A-I      intronic chr15:52904973(-) A-I      intronic chr15:52927846(-) A-I      intronic chr15:52883600(-) A-I      intronic chr15:52929337(-) A-I      intronic chr15:52924137(-) A-I      intronic chr15:52929638(-) A-I      intronic chr15:52935116(-) A-I      intronic chr15:52932583(-) A-I      intronic chr15:52885126(-) A-I      intronic chr15:52885100(-) A-I      intronic chr15:52967993(-) A-I      intronic chr15:52932691(-) A-I      intronic chr15:52885194(-) A-I      intronic chr15:52951059(-) A-I      intronic chr15:52929345(-) A-I      intronic chr15:52929737(-) A-I      intronic chr15:52932600(-) A-I      intronic chr15:52876607(-) A-I      intronic chr15:52930789(-) A-I      intronic chr15:52882162(-) A-I      intronic chr15:52961253(-) A-I      intronic chr15:52936108(-) A-I      intronic chr15:52935685(-) A-I      intronic chr15:52883551(-) A-I      intronic chr15:52935908(-) A-I      intronic chr15:52926579(-) A-I      intronic chr15:52910396(-) A-I      intronic chr15:52935775(-) A-I      intronic chr15:52880813(-) A-I      intronic chr15:52906963(-) A-I      intronic chr15:52932692(-) A-I      intronic chr15:52932724(-) A-I      intronic chr15:52910954(-) A-I      intronic chr15:52956886(-) A-I      intronic chr15:52883592(-) A-I      intronic chr15:52885259(-) A-I      intronic chr15:52935621(-) A-I      intronic chr15:52905321(-) A-I      intronic chr15:52910439(-) A-I      intronic chr15:52957048(-) A-I      intronic chr15:52926931(-) A-I      intronic chr15:52955981(-) A-I      intronic chr15:52885082(-) A-I      intronic chr15:52906499(-) A-I      intronic chr15:52885274(-) A-I      intronic chr15:52932730(-) A-I      intronic chr15:52885187(-) A-I      intronic chr15:52957049(-) A-I      intronic chr15:52961263(-) A-I      intronic chr15:52936102(-) A-I      intronic chr15:52950903(-) A-I      intronic chr15:52967983(-) A-I      intronic chr15:52951146(-) A-I      intronic chr15:52932152(-) A-I      intronic chr15:52917213(-) A-I      intronic chr15:52911921(-) A-I      intronic chr15:52883637(-) A-I      intronic chr15:52932040(-) A-I      intronic chr15:52882149(-) A-I      intronic chr15:52885261(-) A-I      intronic chr15:52917203(-) A-I      intronic chr15:52927087(-) A-I      intronic chr15:52883576(-) A-I      intronic chr15:52931976(-) A-I      intronic chr15:52885152(-) A-I      intronic chr15:52937379(-) A-I      intronic chr15:52906435(-) A-I      intronic chr15:52955984(-) A-I      intronic chr15:52926937(-) A-I      intronic chr15:52935859(-) A-I      intronic chr15:52882155(-) A-I      intronic chr15:52906962(-) A-I      intronic chr15:52926465(-) A-I      intronic chr15:52885214(-) A-I      intronic chr15:52950944(-) A-I      intronic chr15:52911976(-) A-I      intronic chr15:52935038(-) A-I      intronic chr15:52906933(-) A-I      intronic chr15:52936027(-) A-I      intronic chr15:52882217(-) A-I      intronic chr15:52906431(-) A-I      intronic chr15:52932716(-) A-I      intronic chr15:52882052(-) A-I      intronic chr15:52883566(-) A-I      intronic chr15:52935107(-) A-I      intronic chr15:52905451(-) A-I      intronic chr15:52957128(-) A-I      intronic chr15:52955955(-) A-I      intronic chr15:52935617(-) A-I      intronic chr15:52926981(-) A-I      intronic chr15:52910944(-) A-I      intronic chr15:52932639(-) A-I      intronic chr15:52932054(-) A-I      intronic chr15:52904972(-) A-I      intronic chr15:52885220(-) A-I      intronic chr15:52935078(-) A-I      intronic chr15:52885291(-) A-I      intronic chr15:52885309(-) A-I      intronic chr15:52905420(-) A-I      intronic chr15:52914315(-) A-I      intronic chr15:52883725(-) A-I      intronic chr15:52910950(-) A-I      intronic chr15:52885114(-) A-I      intronic chr15:52935705(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FAM214A	chr15:52883576(-) A-I intron -    21960545   //22327324 chr15:52883637(-) A-I intron -    22327324 chr15:52885159(-) A-I intron -    21960545   //22327324 chr15:52885187(-) A-I intron -    21960545   //22327324 chr15:52885259(-) A-I intron -    22327324 chr15:52885309(-) A-I intron -    21960545   //22327324 chr15:52929638(-) A-I intron -    21960545   //22327324 chr15:52961163(-) A-I intron -    22028664 chr15:52961175(-) A-I intron -    22028664 chr15:52961243(-) A-I intron -    22028664 chr15:52961252(-) A-I intron -    22028664 chr15:52961263(-) A-I intron -    22028664 chr15:52961279(-) A-I intron -    22028664 chr15:52961294(-) A-I intron -    22028664 chr15:52961307(-) A-I intron -    22028664 chr15:52961312(-) A-I intron -    22028664 chr15:52961347(-) A-I intron -    22028664 chr15:52961352(-) A-I intron -    22028664 chr15:52961355(-) A-I intron -    22028664 chr15:52883725(-) A-I intron -    21960545 chr15:52885152(-) A-I intron -    21960545 chr15:52882052(-) A-I intron -    21960545 chr15:52882217(-) A-I intron -    21960545 chr15:52885100(-) A-I intron -    21960545 chr15:52885220(-) A-I intron -    21960545 chr15:52885291(-) A-I intron -    21960545 chr15:52885310(-) A-I intron -    21960545 chr15:52906273(-) A-I intron -    21960545 chr15:52910997(-) A-I intron -    21960545 chr15:52914143(-) A-I intron -    21960545 chr15:52914171(-) A-I intron -    21960545 chr15:52914208(-) A-I intron -    21960545 chr15:52926520(-) A-I intron -    21960545 chr15:52929269(-) A-I intron -    21960545 chr15:52929337(-) A-I intron -    21960545 chr15:52929345(-) A-I intron -    21960545 chr15:52929637(-) A-I intron -    21960545 chr15:52935107(-) A-I intron -    21960545 chr15:52955920(-) A-I intron -    21960545 chr15:52955981(-) A-I intron -    21960545 chr15:52955984(-) A-I intron -    21960545 chr15:52956065(-) A-I intron -    21960545 chr15:52956073(-) A-I intron -    21960545 chr15:52957011(-) A-I intron -    21960545 chr15:52957013(-) A-I intron -    21960545 chr15:52965425(-) A-I intron -    21960545 chr15:52965776(-) A-I intron -    21960545 chr15:52965789(-) A-I intron -    21960545 chr15:52882052(-) A-G intron -    22484847 chr15:52882162(-) A-G intron -    22484847 chr15:52882167(-) A-G intron -    22484847 chr15:52882264(-) A-G intron -    22484847 chr15:52883576(-) A-G intron -    22484847 chr15:52883592(-) A-G intron -    22484847 chr15:52883599(-) A-G intron -    22484847 chr15:52883630(-) A-G intron -    22484847 chr15:52883637(-) A-G intron -    22484847 chr15:52885152(-) A-G intron -    22484847 chr15:52885187(-) A-G intron -    22484847 chr15:52885193(-) A-G intron -    22484847 chr15:52885220(-) A-G intron -    22484847 chr15:52885234(-) A-G intron -    22484847 chr15:52885259(-) A-G intron -    22484847 chr15:52885291(-) A-G intron -    22484847 chr15:52885309(-) A-G intron -    22484847 chr15:52935775(-) A-G intron -    22484847 chr15:52937379(-) A-G intron -    22484847 chr15:52961263(-) A-G intron -    22484847 chr15:52961279(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FAM214A	chr15:52873738-52873739(-) m6A 3'UTR//exon       27773535 chr15:52897382-52897383(-) m6A CDS//exon       27773535 chr15:52897407-52897408(-) m6A CDS//exon       24981863//27773535 chr15:52897428-52897429(-) m6A CDS//exon       24981863//27773535 chr15:52897439-52897440(-) m6A CDS//exon       24981863//27773535 chr15:52900807-52900808(-) m6A CDS       24981863//27773535//22608085 chr15:52900834-52900835(-) m6A CDS       24981863//27773535//22608085 chr15:52900875-52900876(-) m6A CDS       24981863//27773535//22608085 chr15:52900891-52900892(-) m6A CDS       24981863//27773535//22608085 chr15:52900973-52900974(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52900990-52900991(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52901020-52901021(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52901119-52901120(-) m6A CDS       24981863//27773535//22608085 chr15:52901163-52901164(-) m6A CDS       24981863//27773535//22608085 chr15:52901193-52901194(-) m6A CDS       24981863//27773535//22608085 chr15:52901302-52901303(-) m6A CDS       24981863//27773535//22608085 chr15:52901309-52901310(-) m6A CDS       24981863//27773535//22608085 chr15:52901347-52901348(-) m6A CDS       24981863//27773535//22608085 chr15:52901366-52901367(-) m6A CDS       24981863//27773535//22608085 chr15:52901373-52901374(-) m6A CDS       24981863//27773535//22608085 chr15:52901437-52901438(-) m6A CDS       27773535 chr15:52901455-52901456(-) m6A CDS       27773535 chr15:52901530-52901531(-) m6A CDS       27773535 chr15:52901699-52901700(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52901744-52901745(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52901759-52901760(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52901766-52901767(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52901794-52901795(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52901889-52901890(-) m6A CDS       24981863//27773535//22608085 chr15:52902035-52902036(-) m6A CDS       27773535//22608085 chr15:52902107-52902108(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902119-52902120(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902176-52902177(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902213-52902214(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902290-52902291(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902300-52902301(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902325-52902326(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902339-52902340(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902371-52902372(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902378-52902379(-) m6A CDS       24284625//24981863//27773535//22608085 chr15:52902456-52902457(-) m6A CDS       24981863 chr15:52970207-52970208(-) m6A 5'UTR//CDS       - chr15:52970265-52970266(-) m6A 5'UTR       - chr15:52970883-52970884(-) m6A 5'UTR//intron       25456834 chr15:52970914-52970915(-) m6A 5'UTR//intron       25456834 chr15:52970942-52970943(-) m6A 5'UTR//intron       24284625//25456834//24981863 chr15:52971062-52971063(-) m6A 5'UTR//intron       24284625//25456834//24981863 chr15:52971506-52971507(-) m6A 5'UTR//intron       25456834//24981863//27371828 chr15:52971552-52971553(-) m6A 5'UTR//intron       25456834//24981863//27371828 chr15:52971566-52971567(-) m6A 5'UTR//intron       25456834//24981863//27371828 chr15:53001935-53001936(-) m6A 5'UTR       25456834//24981863//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3121-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	FAM214A	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3121-3p
Interactor2: FAM214A

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.