Detail Information

Basic Information:


  VIRBase ID:  

HHID00072044

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:           PPP1R12C:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3121-3p PPP1R12C
miRBase
Accession/Entrez ID		 MIMAT0014983 54776
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AAVS1//LENG3//MBS85//p84//p85

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3121-3p
rs1006143795 chr1:180438334    T/C
rs778817728 chr1:180438323    T/C
rs887772082 chr1:180438327    C/T
rs911596096 chr1:180438331    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PPP1R12C
chr19:55620722(-) A-I      intronic
chr19:55617228(-) A-I      intronic
chr19:55620716(-) A-I      intronic
chr19:55620245(-) A-I      intronic
chr19:55620223(-) A-I      intronic
chr19:55615959(-) A-I      intronic
chr19:55620199(-) A-I      intronic
chr19:55620730(-) A-I      intronic
chr19:55618699(-) A-I      intronic
chr19:55612564(-) A-I      intronic
chr19:55616549(-) A-I      intronic
chr19:55620654(-) A-I      intronic
chr19:55615963(-) A-I      intronic
chr19:55620277(-) A-I      intronic
chr19:55616064(-) A-I      intronic
chr19:55616222(-) A-I      intronic
chr19:55618616(-) A-I      intronic
chr19:55618614(-) A-I      intronic
chr19:55618525(-) A-I      intronic
chr19:55617296(-) A-I      intronic
chr19:55617215(-) A-I      intronic
chr19:55617097(-) A-I      intronic
chr19:55619780(-) A-I      intronic
chr19:55616499(-) A-I      intronic
chr19:55616263(-) A-I      intronic
chr19:55616272(-) A-I      intronic
chr19:55619771(-) A-I      intronic
chr19:55618660(-) A-I      intronic
chr19:55619497(-) A-I      intronic
chr19:55619584(-) A-I      intronic
chr19:55620747(-) A-I      intronic
chr19:55620738(-) A-I      intronic
chr19:55612152(-) A-I      intronic
chr19:55612226(-) A-I      intronic
chr19:55620717(-) A-I      intronic
chr19:55612253(-) A-I      intronic
chr19:55612494(-) A-I      intronic
chr19:55612613(-) A-I      intronic
chr19:55615859(-) A-I      intronic
chr19:55615888(-) A-I      intronic
chr19:55615891(-) A-I      intronic
chr19:55620709(-) A-I      intronic
chr19:55620627(-) A-I      intronic
chr19:55620334(-) A-I      intronic
chr19:55620755(-) A-I      intronic
chr19:55615988(-) A-I      intronic
chr19:55616411(-) A-I      intronic
chr19:55616308(-) A-I      intronic
chr19:55615276(-) A-I      intronic
chr19:55618700(-) A-I      intronic
chr19:55615313(-) A-I      intronic
chr19:55612534(-) A-I      intronic
chr19:55612078(-) A-I      intronic
chr19:55612181(-) A-I      intronic
chr19:55620267(-) A-I      intronic
chr19:55617058(-) A-I      intronic
chr19:55620112(-) A-I      intronic
chr19:55619753(-) A-I      intronic
chr19:55619779(-) A-I      intronic
chr19:55612175(-) A-I      intronic
chr19:55615449(-) A-I      intronic
chr19:55612453(-) A-I      intronic
chr19:55620669(-) A-I      intronic
chr19:55612533(-) A-I      intronic
chr19:55616469(-) A-I      intronic
chr19:55622116(-) A-I      intronic
chr19:55619842(-) A-I      intronic
chr19:55620212(-) A-I      intronic
chr19:55612516(-) A-I      intronic
chr19:55612086(-) A-I      intronic
chr19:55622036(-) A-I      intronic
chr19:55612016(-) A-I      intronic
chr19:55616052(-) A-I      intronic
chr19:55619517(-) A-I      intronic
chr19:55616047(-) A-I      intronic
chr19:55615962(-) A-I      intronic
chr19:55616251(-) A-I      intronic
chr19:55620247(-) A-I      intronic
chr19:55620576(-) A-I      intronic
chr19:55615958(-) A-I      intronic
chr19:55619458(-) A-I      intronic
chr19:55620693(-) A-I      intronic
chr19:55620268(-) A-I      intronic
chr19:55614556(-) A-I      intronic
chr19:55620739(-) A-I      intronic
chr19:55619752(-) A-I      intronic
chr19:55615923(-) A-I      intronic
chr19:55612434(-) A-I      intronic
chr19:55615908(-) A-I      intronic
chr19:55620177(-) A-I      intronic
chr19:55617141(-) A-I      intronic
chr19:55615890(-) A-I      intronic
chr19:55612444(-) A-I      intronic
chr19:55615995(-) A-I      intronic
chr19:55618590(-) A-I      intronic
chr19:55622176(-) A-I      intronic
chr19:55615326(-) A-I      intronic
chr19:55619442(-) A-I      intronic
chr19:55615409(-) A-I      intronic
chr19:55612361(-) A-I      intronic
chr19:55612118(-) A-I      intronic
chr19:55612073(-) A-I      intronic
chr19:55617210(-) A-I      intronic
chr19:55616260(-) A-I      intronic
chr19:55615826(-) A-I      intronic
chr19:55612145(-) A-I      intronic
chr19:55617142(-) A-I      intronic
chr19:55612382(-) A-I      intronic
chr19:55620745(-) A-I      intronic
chr19:55616531(-) A-I      intronic
chr19:55619804(-) A-I      intronic
chr19:55617096(-) A-I      intronic
chr19:55616410(-) A-I      intronic
chr19:55616237(-) A-I      intronic
chr19:55622049(-) A-I      intronic
chr19:55615827(-) A-I      intronic
chr19:55615971(-) A-I      intronic
chr19:55620213(-) A-I      intronic
chr19:55612515(-) A-I      intronic
chr19:55617261(-) A-I      intronic
chr19:55616367(-) A-I      intronic
chr19:55620142(-) A-I      intronic
chr19:55612102(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PPP1R12C
chr19:55612102(-) A-G intron -    22484847
chr19:55615827(-) A-G intron -    22484847
chr19:55615958(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PPP1R12C
chr19:55602543-55602544(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr19:55602572-55602573(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:55602579-55602580(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:55602590-55602591(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:55602608-55602609(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:55602706-55602707(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr19:55602714-55602715(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr19:55602768-55602769(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:55602829-55602830(-) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085
chr19:55602851-55602852(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085
chr19:55603238-55603239(-) m6A CDS//exon       24284625//24209618//27371828//27773536//22575960
chr19:55603639-55603640(-) m6A CDS//exon       24284625//24209618//27371828//27773536//22575960
chr19:55603843-55603844(-) Cm CDS//exon       -
chr19:55603851-55603852(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27371828//27773536
chr19:55603864-55603865(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27371828//27773536
chr19:55604207-55604208(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960
chr19:55604406-55604407(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960
chr19:55604442-55604443(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960
chr19:55604584-55604585(-) m6A CDS//exon       24284625//27371828//27773536
chr19:55606037-55606038(-) m6A CDS//exon       24284625//25456834//27773535//27371828//27773536
chr19:55606046-55606047(-) m6A CDS//exon       24284625//25456834//27773535//27371828//27773536
chr19:55606130-55606131(-) m6A CDS//exon       24284625//25456834//27773535//27371828//27773536
chr19:55606823-55606824(-) m6A CDS       24284625//27773536
chr19:55606886-55606887(-) m6A CDS       24284625//27371828//27773536
chr19:55606925-55606926(-) m6A CDS       24284625//27371828//27773536
chr19:55607284-55607285(-) m6A CDS       24284625//27371828//27773536
chr19:55607291-55607292(-) m6A CDS       24284625//27371828//27773536
chr19:55607429-55607430(-) m1A CDS       26863196
chr19:55607498-55607499(-) m6A CDS//exon       24284625//27371828//27773536
chr19:55607637-55607638(-) m6A CDS//exon       24284625//27371828//27773536
chr19:55607695-55607696(-) m6A CDS//exon       27371828//27773536
chr19:55608223-55608224(-) m6A exon//intron       27371828//27773536
chr19:55608253-55608254(-) m6A exon//intron       27371828//27773536
chr19:55608283-55608284(-) m6A exon//intron       27371828//27773536
chr19:55608313-55608314(-) m6A exon//intron       27371828//27773536
chr19:55608323-55608324(-) m6A exon//intron       25456834//27371828//27773536
chr19:55608345-55608346(-) m6A exon//intron       25456834//27371828//27773536
chr19:55608377-55608378(-) m6A exon//intron       24284625//25456834//27371828
chr19:55608409-55608410(-) m6A exon//intron       24284625//25456834//27371828
chr19:55610160-55610161(-) m6A CDS       24284625//25456834//27371828//27773536
chr19:55610172-55610173(-) m6A CDS       24284625//25456834//27371828//27773536
chr19:55610334-55610335(-) m6A CDS       24284625//25456834//27371828//27773536
chr19:55610410-55610411(-) m6A CDS       27371828//27773536
chr19:55622844-55622845(-) m6A exon//intron       24284625
chr19:55623026-55623027(-) m6A exon//intron       -
chr19:55623890-55623891(-) m6A CDS//exon       24284625
chr19:55623902-55623903(-) m6A CDS//exon       24284625
chr19:55623983-55623984(-) m6A exon//intron       24284625
chr19:55624006-55624007(-) m6A exon//intron       24284625
chr19:55624092-55624093(-) m6A CDS//exon       -
chr19:55624101-55624102(-) m6A CDS//exon       -
chr19:55628627-55628628(-) m6A CDS       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3121-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
PPP1R12C
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3121-3p
Interactor2: PPP1R12C

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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