Detail Information

Basic Information:


  VIRBase ID:  

HHID00072026

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:           SEPHS1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3121-3p SEPHS1
miRBase
Accession/Entrez ID		 MIMAT0014983 22929
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - SELD//SPS//SPS1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3121-3p
rs1006143795 chr1:180438334    T/C
rs778817728 chr1:180438323    T/C
rs887772082 chr1:180438327    C/T
rs911596096 chr1:180438331    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SEPHS1
chr10:13384771(-) A-I      intronic
chr10:13384972(-) A-I      intronic
chr10:13384953(-) A-I      intronic
chr10:13384803(-) A-I      intronic
chr10:13383939(-) A-I      intronic
chr10:13384472(-) A-I      intronic
chr10:13366684(-) A-I      intronic
chr10:13375202(-) A-I      intronic
chr10:13365534(-) A-I      intronic
chr10:13384534(-) A-I      intronic
chr10:13384798(-) A-I      intronic
chr10:13384928(-) A-I      intronic
chr10:13375226(-) A-I      intronic
chr10:13384936(-) A-I      intronic
chr10:13385751(-) A-I      intronic
chr10:13375473(-) A-I      intronic
chr10:13384523(-) A-I      intronic
chr10:13375230(-) A-I      intronic
chr10:13384864(-) A-I      intronic
chr10:13367734(-) A-I      intronic
chr10:13366645(-) A-I      intronic
chr10:13365878(-) A-I      intronic
chr10:13362709(-) A-I      intronic
chr10:13365457(-) A-I      intronic
chr10:13375691(-) A-I      intronic
chr10:13365876(-) A-I      intronic
chr10:13384833(-) A-I      intronic
chr10:13363412(-) A-I      intronic
chr10:13384904(-) A-I      intronic
chr10:13385610(-) A-I      intronic
chr10:13368994(-) A-I      intronic
chr10:13384968(-) A-I      intronic
chr10:13368412(-) A-I      intronic
chr10:13383913(-) A-I      intronic
chr10:13367749(-) A-I      intronic
chr10:13362741(-) A-I      intronic
chr10:13375729(-) A-I      intronic
chr10:13369132(-) A-I      intronic
chr10:13362278(-) A-I      intronic
chr10:13365361(-) A-I      intronic
chr10:13375231(-) A-I      intronic
chr10:13385649(-) A-I      intronic
chr10:13368733(-) A-I      intronic
chr10:13376588(-) A-I      intronic
chr10:13375715(-) A-I      intronic
chr10:13375719(-) A-I      intronic
chr10:13362320(-) A-I      intronic
chr10:13385597(-) A-I      intronic
chr10:13368747(-) A-I      intronic
chr10:13369141(-) A-I      intronic
chr10:13369239(-) A-I      intronic
chr10:13363421(-) A-I      intronic
chr10:13384796(-) A-I      intronic
chr10:13368758(-) A-I      intronic
chr10:13369046(-) A-I      intronic
chr10:13368742(-) A-I      intronic
chr10:13362806(-) A-I      intronic
chr10:13384819(-) A-I      intronic
chr10:13368805(-) A-I      intronic
chr10:13384476(-) A-I      intronic
chr10:13375537(-) A-I      intronic
chr10:13365823(-) A-I      intronic
chr10:13366785(-) A-I      intronic
chr10:13362795(-) A-I      intronic
chr10:13384975(-) A-I      intronic
chr10:13362687(-) A-I      intronic
chr10:13385702(-) A-I      intronic
chr10:13362745(-) A-I      intronic
chr10:13361602(-) A-I      intronic
chr10:13362719(-) A-I      intronic
chr10:13374662(-) A-I      intronic
chr10:13363511(-) A-I      intronic
chr10:13364405(-) A-I      intronic
chr10:13365519(-) A-I      intronic
chr10:13369172(-) A-I      intronic
chr10:13362789(-) A-I      intronic
chr10:13385579(-) A-I      intronic
chr10:13383752(-) A-I      intronic
chr10:13368624(-) A-I      intronic
chr10:13364392(-) A-I      intronic
chr10:13384874(-) A-I      intronic
chr10:13365440(-) A-I      intronic
chr10:13362746(-) A-I      intronic
chr10:13384510(-) A-I      intronic
chr10:13385007(-) A-I      intronic
chr10:13385016(-) A-I      intronic
chr10:13362431(-) A-I      intronic
chr10:13369129(-) A-I      intronic
chr10:13368812(-) A-I      intronic
chr10:13362771(-) A-I      intronic
chr10:13384814(-) A-I      intronic
chr10:13362776(-) A-I      intronic
chr10:13384378(-) A-I      intronic
chr10:13363464(-) A-I      intronic
chr10:13366750(-) A-I      intronic
chr10:13384808(-) A-I      intronic
chr10:13384962(-) A-I      intronic
chr10:13385014(-) A-I      intronic
chr10:13375406(-) A-I      intronic
chr10:13368645(-) A-I      intronic
chr10:13368671(-) A-I      intronic
chr10:13365452(-) A-I      intronic
chr10:13384524(-) A-I      intronic
chr10:13366732(-) A-I      intronic
chr10:13361608(-) A-I      intronic
chr10:13368640(-) A-I      intronic
chr10:13368608(-) A-I      intronic
chr10:13369055(-) A-I      intronic
chr10:13367776(-) A-I      intronic
chr10:13385008(-) A-I      intronic
chr10:13384918(-) A-I      intronic
chr10:13362254(-) A-I      intronic
chr10:13384954(-) A-I      intronic
chr10:13362671(-) A-I      intronic
chr10:13368663(-) A-I      intronic
chr10:13368602(-) A-I      intronic
chr10:13365377(-) A-I      intronic
chr10:13384967(-) A-I      intronic
chr10:13385757(-) A-I      intronic
chr10:13383912(-) A-I      intronic
chr10:13385652(-) A-I      intronic
chr10:13362661(-) A-I      intronic
chr10:13383740(-) A-I      intronic
chr10:13385570(-) A-I      intronic
chr10:13385752(-) A-I      intronic
chr10:13385557(-) A-I      intronic
chr10:13384821(-) A-I      intronic
chr10:13374654(-) A-I      intronic
chr10:13366787(-) A-I      intronic
chr10:13385549(-) A-I      intronic
chr10:13368686(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SEPHS1
chr10:13359582(-) T-C exon 3'UTR    21725310
chr10:13384814(-) A-G intron -    22484847
chr10:13384918(-) A-G intron -    22484847
chr10:13384962(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SEPHS1
chr10:13359427-13359428(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr10:13359443-13359444(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr10:13359475-13359476(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr10:13359521-13359522(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr10:13359536-13359537(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr10:13359584-13359585(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr10:13359622-13359623(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr10:13359706-13359707(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr10:13360530-13360531(-) m6A 3'UTR       24981863
chr10:13360541-13360542(-) m6A 3'UTR       24981863
chr10:13360772-13360773(-) Y 3'UTR       26075521
chr10:13361065-13361066(-) m6A 3'UTR       24981863//22608085
chr10:13361072-13361073(-) m6A 3'UTR       24981863//22608085
chr10:13361135-13361136(-) m6A 3'UTR       24981863//22608085
chr10:13361217-13361218(-) m6A CDS       24981863//27773535//22608085
chr10:13363984-13363985(-) m6A intron       27773535
chr10:13364040-13364041(-) m6A intron       27773535
chr10:13364852-13364853(-) m6A CDS//intron       22575960
chr10:13364875-13364876(-) m6A CDS//intron       27773536//22575960
chr10:13364968-13364969(-) m6A CDS//intron       27773535//27371828//27773536//22575960
chr10:13365039-13365040(-) m6A CDS//intron       27773535//27773536//22575960
chr10:13370353-13370354(-) m6A CDS       27773535//27773536//22575960
chr10:13370373-13370374(-) m6A CDS       27773535//27773536
chr10:13370426-13370427(-) m6A CDS       27773535
chr10:13371735-13371736(-) m6A CDS       27773535
chr10:13371745-13371746(-) m6A CDS       27773535
chr10:13371782-13371783(-) m6A CDS       27773535
chr10:13375876-13375877(-) m6A CDS       27773535
chr10:13375886-13375887(-) m6A CDS       27773535
chr10:13375907-13375908(-) m6A CDS       27773535
chr10:13380748-13380749(-) m6A CDS//exon       27773535
chr10:13382729-13382730(-) m6A 5'UTR//intron       27773535
chr10:13386807-13386808(-) m6A CDS//exon//intron       24284625//24209618//24981863//27371828//22608085
chr10:13386875-13386876(-) m6A CDS//exon//intron       24284625//24209618//24981863//27371828//22608085
chr10:13386906-13386907(-) m6A CDS//exon//intron       24284625//24209618//24981863//27371828//22608085
chr10:13386952-13386953(-) m6A 5'UTR//exon//intron       24284625//24209618//24981863//27371828//22608085
chr10:13387012-13387013(-) m6A 5'UTR//exon//intron       24284625//24209618//24981863//27773535//27371828
chr10:13390233-13390234(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3121-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
SEPHS1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3121-3p
Interactor2: SEPHS1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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