Detail Information

Basic Information:


  VIRBase ID:  

HHID00072022

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:           RASGRP1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3121-3p RASGRP1
miRBase
Accession/Entrez ID		 MIMAT0014983 10125
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CALDAG-GEFI//CALDAG-GEFII//IMD64//RASGRP

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3121-3p
rs1006143795 chr1:180438334    T/C
rs778817728 chr1:180438323    T/C
rs887772082 chr1:180438327    C/T
rs911596096 chr1:180438331    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RASGRP1
chr15:38834343(-) A-I      intronic
chr15:38834312(-) A-I      intronic
chr15:38798753(-) A-I      intronic
chr15:38798760(-) A-I      intronic
chr15:38798741(-) A-I      intronic
chr15:38833669(-) A-I      intronic
chr15:38832242(-) A-I      intronic
chr15:38832180(-) A-I      intronic
chr15:38816352(-) A-I      intronic
chr15:38838521(-) A-I      intronic
chr15:38838511(-) A-I      intronic
chr15:38792671(-) A-I      intronic
chr15:38816369(-) A-I      intronic
chr15:38838702(-) A-I      intronic
chr15:38838656(-) A-I      intronic
chr15:38816339(-) A-I      intronic
chr15:38832404(-) A-I      intronic
chr15:38838504(-) A-I      intronic
chr15:38833709(-) A-I      intronic
chr15:38840592(-) A-I      intronic
chr15:38816370(-) A-I      intronic
chr15:38838602(-) A-I      intronic
chr15:38840698(-) A-I      intronic
chr15:38838593(-) A-I      intronic
chr15:38833589(-) A-I      intronic
chr15:38838442(-) A-I      intronic
chr15:38838529(-) A-I      intronic
chr15:38833774(-) A-I      intronic
chr15:38817426(-) A-I      intronic
chr15:38838655(-) A-I      intronic
chr15:38817455(-) A-I      intronic
chr15:38816402(-) A-I      intronic
chr15:38794162(-) A-I      intronic
chr15:38832256(-) A-I      intronic
chr15:38834313(-) A-I      intronic
chr15:38830348(-) A-I      intronic
chr15:38832225(-) A-I      intronic
chr15:38834333(-) A-I      intronic
chr15:38817370(-) A-I      intronic
chr15:38838703(-) A-I      intronic
chr15:38798666(-) A-I      intronic
chr15:38833710(-) A-I      intronic
chr15:38840598(-) A-I      intronic
chr15:38840650(-) A-I      intronic
chr15:38834390(-) A-I      intronic
chr15:38833693(-) A-I      intronic
chr15:38830341(-) A-I      intronic
chr15:38792704(-) A-I      intronic
chr15:38798784(-) A-I      intronic
chr15:38840692(-) A-I      intronic
chr15:38792740(-) A-I      intronic
chr15:38792748(-) A-I      intronic
chr15:38816382(-) A-I      intronic
chr15:38834366(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RASGRP1
chr15:38817455(-) A-I intron -    22327324
chr15:38817455(-) A-G intron -    22484847
chr15:38832225(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RASGRP1
chr15:38786818-38786819(-) m6A 3'UTR//CDS//intron       27371828
chr15:38786896-38786897(-) m6A 3'UTR//CDS//intron       27371828
chr15:38786921-38786922(-) m6A 3'UTR//CDS//intron       27371828
chr15:38852079-38852080(-) m6A CDS       27371828
chr15:38852166-38852167(-) m6A 5'UTR//CDS       27371828//27773536
chr15:38852202-38852203(-) m6A 5'UTR//CDS       27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3121-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
RASGRP1
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3121-3p
Interactor2: RASGRP1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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