Basic Information:

  VIRBase ID:  

HHID00072013

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:  MIMAT0014983          BTG2:  NM_006763     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3121-3p	BTG2
miRBase Accession/Entrez ID	MIMAT0014983	7832
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	APRO1//PC3//TIS21

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3121-3p	rs1006143795 chr1:180438334    T/C rs778817728 chr1:180438323    T/C rs887772082 chr1:180438327    C/T rs911596096 chr1:180438331    G/C

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	BTG2	chr1:203274684-203274685(+) m6A 5'UTR       24284625//25456834//24981863//26404942//22608085 chr1:203274704-203274705(+) m6A 5'UTR       24284625//25456834//24981863//26404942//22608085 chr1:203274752-203274753(+) m6A CDS       24284625//25456834//24981863//26404942//22608085 chr1:203274809-203274810(+) m6A CDS       24284625//24209618//24981863//22608085 chr1:203276241-203276242(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr1:203276312-203276313(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr1:203276346-203276347(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr1:203276402-203276403(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr1:203276504-203276505(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr1:203276540-203276541(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr1:203276644-203276645(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr1:203276708-203276709(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr1:203276786-203276787(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr1:203276851-203276852(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr1:203276933-203276934(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22608085 chr1:203277005-203277006(+) m6A 3'UTR//intron       24284625//25456834//24981863//26404942//22608085 chr1:203277053-203277054(+) m6A 3'UTR//intron       24284625//26404942 chr1:203277059-203277060(+) m6A 3'UTR//intron       24284625//26404942 chr1:203277260-203277261(+) m6A 3'UTR//intron       26404942 chr1:203277292-203277293(+) m6A 3'UTR//intron       26404942 chr1:203277304-203277305(+) m6A 3'UTR//intron       26404942 chr1:203277380-203277381(+) m6A 3'UTR//intron       26404942 chr1:203277418-203277419(+) m6A 3'UTR//intron       26404942 chr1:203277433-203277434(+) m6A 3'UTR//intron       26404942 chr1:203277931-203277932(+) m6A 3'UTR//intron       26404942 chr1:203277990-203277991(+) m6A 3'UTR//intron       26404942 chr1:203278039-203278040(+) m6A 3'UTR//intron       26404942 chr1:203278055-203278056(+) m6A 3'UTR//intron       26404942 chr1:203278075-203278076(+) m6A 3'UTR//intron       26404942 chr1:203278203-203278204(+) m6A 3'UTR//intron       24284625//24209618//24981863//26404942 chr1:203278239-203278240(+) m6A 3'UTR//intron       24284625//24209618//24981863//26404942 chr1:203278310-203278311(+) m6A 3'UTR       24284625//24981863 chr1:203278357-203278358(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3121-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	BTG2	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3121-3p
Interactor2: BTG2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.