Basic Information:

  VIRBase ID:  

HHID00072011

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:  MIMAT0014983          KDM6A:  NR_111960     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3121-3p	KDM6A
miRBase Accession/Entrez ID	MIMAT0014983	7403
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	bA386N14.2//KABUK2//UTX

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3121-3p	rs1006143795 chr1:180438334    T/C rs778817728 chr1:180438323    T/C rs887772082 chr1:180438327    C/T rs911596096 chr1:180438331    G/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	KDM6A	chrX:44743202(+) A-I      intronic chrX:44742471(+) A-I      intronic chrX:44761705(+) A-I      intronic chrX:44800133(+) A-I      intronic chrX:44797485(+) A-I      intronic chrX:44797439(+) A-I      intronic chrX:44792272(+) A-I      intronic chrX:44792262(+) A-I      intronic chrX:44788351(+) A-I      intronic chrX:44788333(+) A-I      intronic chrX:44771543(+) A-I      intronic chrX:44940198(+) A-I      intronic chrX:44912068(+) A-I      intronic chrX:44771396(+) A-I      intronic chrX:44766622(+) A-I      intronic chrX:44743300(+) A-I      intronic chrX:44761817(+) A-I      intronic chrX:44761740(+) A-I      intronic chrX:44761397(+) A-I      intronic chrX:44743327(+) A-I      intronic chrX:44743331(+) A-I      intronic chrX:44744897(+) A-I      intronic chrX:44902888(+) A-I      intronic chrX:44765535(+) A-I      intronic chrX:44738004(+) A-I      intronic chrX:44761388(+) A-I      intronic chrX:44744929(+) A-I      intronic chrX:44743191(+) A-I      intronic chrX:44784524(+) A-I      intronic chrX:44761320(+) A-I      intronic chrX:44743178(+) A-I      intronic chrX:44743171(+) A-I      intronic chrX:44761272(+) A-I      intronic chrX:44744931(+) A-I      intronic chrX:44744966(+) A-I      intronic chrX:44761263(+) A-I      intronic chrX:44745049(+) A-I      intronic chrX:44745071(+) A-I      intronic chrX:44745755(+) A-I      intronic chrX:44745835(+) A-I      intronic chrX:44745836(+) A-I      intronic chrX:44745853(+) A-I      intronic chrX:44745891(+) A-I      intronic chrX:44745934(+) A-I      intronic chrX:44742758(+) A-I      intronic chrX:44746245(+) A-I      intronic chrX:44746366(+) A-I      intronic chrX:44746375(+) A-I      intronic chrX:44746395(+) A-I      intronic chrX:44747107(+) A-I      intronic chrX:44747115(+) A-I      intronic chrX:44747133(+) A-I      intronic chrX:44747166(+) A-I      intronic chrX:44747221(+) A-I      intronic chrX:44747298(+) A-I      intronic chrX:44747355(+) A-I      intronic chrX:44747375(+) A-I      intronic chrX:44747389(+) A-I      intronic chrX:44747390(+) A-I      intronic chrX:44747393(+) A-I      intronic chrX:44747395(+) A-I      intronic chrX:44747398(+) A-I      intronic chrX:44747399(+) A-I      intronic chrX:44742748(+) A-I      intronic chrX:44747404(+) A-I      intronic chrX:44747511(+) A-I      intronic chrX:44761258(+) A-I      intronic chrX:44761253(+) A-I      intronic chrX:44760507(+) A-I      intronic chrX:44760442(+) A-I      intronic chrX:44760441(+) A-I      intronic chrX:44760432(+) A-I      intronic chrX:44760429(+) A-I      intronic chrX:44745865(+) A-I      intronic chrX:44760032(+) A-I      intronic chrX:44759985(+) A-I      intronic chrX:44759984(+) A-I      intronic chrX:44759961(+) A-I      intronic chrX:44759957(+) A-I      intronic chrX:44736347(+) A-I      intronic chrX:44759907(+) A-I      intronic chrX:44736325(+) A-I      intronic chrX:44736319(+) A-I      intronic chrX:44736315(+) A-I      intronic chrX:44757049(+) A-I      intronic chrX:44756953(+) A-I      intronic chrX:44753966(+) A-I      intronic chrX:44736305(+) A-I      intronic chrX:44736277(+) A-I      intronic chrX:44753961(+) A-I      intronic chrX:44752940(+) A-I      intronic chrX:44752937(+) A-I      intronic chrX:44752931(+) A-I      intronic chrX:44747558(+) A-I      intronic chrX:44748403(+) A-I      intronic chrX:44752895(+) A-I      intronic chrX:44752885(+) A-I      intronic chrX:44752855(+) A-I      intronic chrX:44752836(+) A-I      intronic chrX:44748441(+) A-I      intronic chrX:44752327(+) A-I      intronic chrX:44752299(+) A-I      intronic chrX:44742736(+) A-I      intronic chrX:44742712(+) A-I      intronic chrX:44742642(+) A-I      intronic chrX:44751531(+) A-I      intronic chrX:44760377(+) A-I      intronic chrX:44751784(+) A-I      intronic chrX:44751834(+) A-I      intronic chrX:44752088(+) A-I      intronic chrX:44752091(+) A-I      intronic chrX:44752102(+) A-I      intronic chrX:44742552(+) A-I      intronic chrX:44742506(+) A-I      intronic chrX:44741119(+) A-I      intronic chrX:44741100(+) A-I      intronic chrX:44741075(+) A-I      intronic chrX:44752106(+) A-I      intronic chrX:44752190(+) A-I      intronic chrX:44740964(+) A-I      intronic chrX:44741004(+) A-I      intronic chrX:44752897(+) A-I      intronic chrX:44963427(+) A-I      intronic chrX:44963347(+) A-I      intronic chrX:44963334(+) A-I      intronic chrX:44960211(+) A-I      intronic chrX:44960119(+) A-I      intronic chrX:44941500(+) A-I      intronic chrX:44752209(+) A-I      intronic chrX:44941499(+) A-I      intronic chrX:44941406(+) A-I      intronic chrX:44938906(+) A-I      intronic chrX:44912562(+) A-I      intronic chrX:44910484(+) A-I      intronic chrX:44910384(+) A-I      intronic chrX:44909464(+) A-I      intronic chrX:44909408(+) A-I      intronic chrX:44907330(+) A-I      intronic chrX:44907311(+) A-I      intronic chrX:44902902(+) A-I      intronic chrX:44740666(+) A-I      intronic chrX:44740665(+) A-I      intronic chrX:44740571(+) A-I      intronic chrX:44740527(+) A-I      intronic chrX:44740525(+) A-I      intronic chrX:44740521(+) A-I      intronic chrX:44740516(+) A-I      intronic chrX:44740501(+) A-I      intronic chrX:44743305(+) A-I      intronic chrX:44743293(+) A-I      intronic chrX:44743276(+) A-I      intronic chrX:44902863(+) A-I      intronic chrX:44902862(+) A-I      intronic chrX:44902857(+) A-I      intronic chrX:44890174(+) A-I      intronic chrX:44890035(+) A-I      intronic chrX:44890034(+) A-I      intronic chrX:44890010(+) A-I      intronic chrX:44888753(+) A-I      intronic chrX:44888533(+) A-I      intronic chrX:44888524(+) A-I      intronic chrX:44888496(+) A-I      intronic chrX:44887298(+) A-I      intronic chrX:44887260(+) A-I      intronic chrX:44887259(+) A-I      intronic chrX:44886501(+) A-I      intronic chrX:44886483(+) A-I      intronic chrX:44886033(+) A-I      intronic chrX:44886028(+) A-I      intronic chrX:44886012(+) A-I      intronic chrX:44886004(+) A-I      intronic chrX:44855373(+) A-I      intronic chrX:44853032(+) A-I      intronic chrX:44948624(+) A-I      intronic chrX:44853009(+) A-I      intronic chrX:44852958(+) A-I      intronic chrX:44851032(+) A-I      intronic chrX:44851031(+) A-I      intronic chrX:44851001(+) A-I      intronic chrX:44850993(+) A-I      intronic chrX:44849583(+) A-I      intronic chrX:44849582(+) A-I      intronic chrX:44849550(+) A-I      intronic chrX:44826322(+) A-I      intronic chrX:44826179(+) A-I      intronic chrX:44826178(+) A-I      intronic chrX:44823153(+) A-I      intronic chrX:44823082(+) A-I      intronic chrX:44823069(+) A-I      intronic chrX:44823065(+) A-I      intronic chrX:44822505(+) A-I      intronic chrX:44822473(+) A-I      intronic chrX:44816213(+) A-I      intronic chrX:44815785(+) A-I      intronic chrX:44815730(+) A-I      intronic chrX:44813266(+) A-I      intronic chrX:44813191(+) A-I      intronic chrX:44812122(+) A-I      intronic chrX:44811757(+) A-I      intronic chrX:44811703(+) A-I      intronic chrX:44811658(+) A-I      intronic chrX:44811656(+) A-I      intronic chrX:44811652(+) A-I      intronic chrX:44809470(+) A-I      intronic chrX:44809342(+) A-I      intronic chrX:44800182(+) A-I      intronic chrX:44853026(+) A-I      intronic chrX:44886452(+) A-I      intronic chrX:44805387(+) A-I      intronic chrX:44907285(+) A-I      intronic chrX:44816254(+) A-I      intronic chrX:44784208(+) A-I      intronic chrX:44797338(+) A-I      intronic chrX:44748450(+) A-I      intronic chrX:44852990(+) A-I      intronic chrX:44812209(+) A-I      intronic chrX:44742556(+) A-I      intronic chrX:44752364(+) A-I      intronic chrX:44739917(+) A-I      intronic chrX:44742761(+) A-I      intronic chrX:44888576(+) A-I      intronic chrX:44766623(+) A-I      intronic chrX:44752084(+) A-I      intronic chrX:44904670(+) A-I      intronic chrX:44745937(+) A-I      intronic chrX:44813236(+) A-I      intronic chrX:44748362(+) A-I      intronic chrX:44851097(+) A-I      intronic chrX:44743227(+) A-I      intronic chrX:44752087(+) A-I      intronic chrX:44752819(+) A-I      intronic chrX:44746308(+) A-I      intronic chrX:44760372(+) A-I      intronic chrX:44808407(+) A-I      intronic chrX:44747349(+) A-I      intronic chrX:44799354(+) A-I      intronic chrX:44815787(+) A-I      intronic chrX:44752128(+) A-I      intronic chrX:44756927(+) A-I      intronic chrX:44761391(+) A-I      intronic chrX:44771515(+) A-I      intronic chrX:44745881(+) A-I      intronic chrX:44799378(+) A-I      intronic chrX:44948543(+) A-I      intronic chrX:44938889(+) A-I      intronic chrX:44799481(+) A-I      intronic chrX:44755368(+) A-I      intronic chrX:44755449(+) A-I      intronic chrX:44755359(+) A-I      intronic chrX:44755530(+) A-I      intronic chrX:44755465(+) A-I      intronic chrX:44755599(+) A-I      intronic chrX:44755584(+) A-I      intronic chrX:44755459(+) A-I      intronic chrX:44755486(+) A-I      intronic chrX:44755481(+) A-I      intronic chrX:44745478(+) A-I      intronic chrX:44741211(+) A-I      intronic chrX:44748426(+) A-I      intronic chrX:44751994(+) A-I      intronic chrX:44815775(+) A-I      intronic chrX:44739927(+) A-I      intronic chrX:44742389(+) A-I      intronic chrX:44800159(+) A-I      intronic chrX:44743184(+) A-I      intronic chrX:44855345(+) A-I      intronic chrX:44745007(+) A-I      intronic chrX:44816284(+) A-I      intronic chrX:44799551(+) A-I      intronic chrX:44836747(+) A-I      intronic chrX:44808559(+) A-I      intronic chrX:44808519(+) A-I      intronic chrX:44752432(+) A-I      intronic chrX:44941513(+) A-I      intronic chrX:44784149(+) A-I      intronic chrX:44812211(+) A-I      intronic chrX:44886334(+) A-I      intronic chrX:44756838(+) A-I      intronic chrX:44747526(+) A-I      intronic chrX:44959208(+) A-I      intronic chrX:44910524(+) A-I      intronic chrX:44809435(+) A-I      intronic chrX:44745875(+) A-I      intronic chrX:44740600(+) A-I      intronic chrX:44743134(+) A-I      intronic chrX:44743163(+) A-I      intronic chrX:44742882(+) A-I      intronic chrX:44760028(+) A-I      intronic chrX:44851111(+) A-I      intronic chrX:44823439(+) A-I      intronic chrX:44748461(+) A-I      intronic chrX:44852902(+) A-I      intronic chrX:44742395(+) A-I      intronic chrX:44799377(+) A-I      intronic chrX:44752820(+) A-I      intronic chrX:44946254(+) A-I      intronic chrX:44752362(+) A-I      intronic chrX:44752384(+) A-I      intronic chrX:44912491(+) A-I      intronic chrX:44816330(+) A-I      intronic chrX:44748470(+) A-I      intronic chrX:44743159(+) A-I      intronic chrX:44809313(+) A-I      intronic chrX:44941428(+) A-I      intronic chrX:44761896(+) A-I      intronic chrX:44815709(+) A-I      intronic chrX:44743099(+) A-I      intronic chrX:44938882(+) A-I      intronic chrX:44815839(+) A-I      intronic chrX:44744933(+) A-I      intronic chrX:44888522(+) A-I      intronic chrX:44761736(+) A-I      intronic chrX:44742464(+) A-I      intronic chrX:44739260(+) A-I      intronic chrX:44752073(+) A-I      intronic chrX:44808529(+) A-I      intronic chrX:44780392(+) A-I      intronic chrX:44761735(+) A-I      intronic chrX:44747365(+) A-I      intronic chrX:44941522(+) A-I      intronic chrX:44740425(+) A-I      intronic chrX:44740997(+) A-I      intronic chrX:44941429(+) A-I      intronic chrX:44742414(+) A-I      intronic chrX:44739254(+) A-I      intronic chrX:44748323(+) A-I      intronic chrX:44752181(+) A-I      intronic chrX:44849644(+) A-I      intronic chrX:44920760(+) A-I      intronic chrX:44743269(+) A-I      intronic chrX:44822607(+) A-I      intronic chrX:44849716(+) A-I      intronic chrX:44761323(+) A-I      intronic chrX:44740426(+) A-I      intronic chrX:44960198(+) A-I      intronic chrX:44751817(+) A-I      intronic chrX:44809458(+) A-I      intronic chrX:44742780(+) A-I      intronic chrX:44963542(+) A-I      intronic chrX:44813181(+) A-I      intronic chrX:44797346(+) A-I      intronic chrX:44745421(+) A-I      intronic chrX:44948620(+) A-I      intronic chrX:44963365(+) A-I      intronic chrX:44744905(+) A-I      intronic chrX:44907126(+) A-I      intronic chrX:44800003(+) A-I      intronic chrX:44907284(+) A-I      intronic chrX:44822474(+) A-I      intronic chrX:44741063(+) A-I      intronic chrX:44809400(+) A-I      intronic chrX:44771534(+) A-I      intronic chrX:44822550(+) A-I      intronic chrX:44941604(+) A-I      intronic chrX:44742457(+) A-I      intronic chrX:44945815(+) A-I      intronic chrX:44776126(+) A-I      intronic chrX:44910355(+) A-I      intronic chrX:44959031(+) A-I      intronic chrX:44752310(+) A-I      intronic chrX:44941206(+) A-I      intronic chrX:44744892(+) A-I      intronic chrX:44740557(+) A-I      intronic chrX:44756850(+) A-I      intronic chrX:44938837(+) A-I      intronic chrX:44746244(+) A-I      intronic chrX:44817634(+) A-I      intronic chrX:44811698(+) A-I      intronic chrX:44941420(+) A-I      intronic chrX:44757058(+) A-I      intronic chrX:44741117(+) A-I      intronic chrX:44741131(+) A-I      intronic chrX:44816252(+) A-I      intronic chrX:44811646(+) A-I      intronic chrX:44751589(+) A-I      intronic chrX:44907357(+) A-I      intronic chrX:44941611(+) A-I      intronic chrX:44745024(+) A-I      intronic chrX:44823518(+) A-I      intronic chrX:44743201(+) A-I      intronic chrX:44800186(+) A-I      intronic chrX:44751959(+) A-I      intronic chrX:44885955(+) A-I      intronic chrX:44801310(+) A-I      intronic chrX:44752097(+) A-I      intronic chrX:44741108(+) A-I      intronic chrX:44771485(+) A-I      intronic chrX:44743233(+) A-I      intronic chrX:44752353(+) A-I      intronic chrX:44799534(+) A-I      intronic chrX:44744870(+) A-I      intronic chrX:44751556(+) A-I      intronic chrX:44752962(+) A-I      intronic chrX:44740524(+) A-I      intronic chrX:44744971(+) A-I      intronic chrX:44888769(+) A-I      intronic chrX:44890120(+) A-I      intronic chrX:44740998(+) A-I      intronic chrX:44745443(+) A-I      intronic chrX:44801298(+) A-I      intronic chrX:44904669(+) A-I      intronic chrX:44741114(+) A-I      intronic chrX:44761793(+) A-I      intronic chrX:44946340(+) A-I      intronic chrX:44765670(+) A-I      intronic chrX:44742444(+) A-I      intronic chrX:44817632(+) A-I      intronic chrX:44742408(+) A-I      intronic chrX:44803341(+) A-I      intronic chrX:44748427(+) A-I      intronic chrX:44752833(+) A-I      intronic chrX:44757057(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	KDM6A	chrX:44736101(+) A-I intron -    15342557 chrX:44736139(+) A-I intron -    15342557 chrX:44736147(+) A-I intron -    15342557 chrX:44736149(+) A-I intron -    15342557 chrX:44736169(+) A-I intron -    15342557 chrX:44736183(+) A-I intron -    15342557 chrX:44736275(+) A-I intron -    15342557 chrX:44736281(+) A-I intron -    15342557 chrX:44736285(+) A-I intron -    15342557 chrX:44736289(+) A-I intron -    15342557 chrX:44736293(+) A-I intron -    15342557 chrX:44736307(+) A-I intron -    15342557 chrX:44736323(+) A-I intron -    15342557 chrX:44736337(+) A-I intron -    15342557 chrX:44736353(+) A-I intron -    15342557 chrX:44736355(+) A-I intron -    15342557 chrX:44755359(+) A-I intron -    22028664 chrX:44755368(+) A-I intron -    22028664 chrX:44755449(+) A-I intron -    22028664 chrX:44755459(+) A-I intron -    22028664 chrX:44755465(+) A-I intron -    22028664 chrX:44755481(+) A-I intron -    22028664 chrX:44755486(+) A-I intron -    22028664 chrX:44755530(+) A-I intron -    22028664 chrX:44755584(+) A-I intron -    22028664 chrX:44755599(+) A-I intron -    22028664 chrX:44802475(+) A-I intron -    21960545 chrX:44812153(+) A-I intron -    21960545 chrX:44815839(+) A-I intron -    21960545 chrX:44948586(+) A-I intron -    21960545 chrX:44740997(+) A-G intron -    22484847 chrX:44740998(+) A-G intron -    22484847 chrX:44741063(+) A-G intron -    22484847 chrX:44752353(+) A-G intron -    22484847 chrX:44756927(+) A-G intron -    22484847 chrX:44756948(+) A-G intron -    22484847 chrX:44813061(+) A-G intron -    22484847 chrX:44963542(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	KDM6A	chrX:44732949-44732950(+) m6A CDS       - chrX:44732954-44732955(+) m6A CDS       - chrX:44922671-44922672(+) m6A 3'UTR//CDS       24284625//22575960 chrX:44922745-44922746(+) m6A 3'UTR//CDS       24284625//24981863//22575960//22608085 chrX:44922848-44922849(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chrX:44922904-44922905(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chrX:44923006-44923007(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chrX:44923039-44923040(+) m6A 3'UTR//CDS       24284625//24209618//22608085 chrX:44928942-44928943(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:44929023-44929024(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:44929067-44929068(+) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//22575960//22608085 chrX:44929087-44929088(+) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//22575960//22608085 chrX:44929108-44929109(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:44929137-44929138(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:44929226-44929227(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:44929285-44929286(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:44929330-44929331(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:44929405-44929406(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chrX:44929415-44929416(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chrX:44929501-44929502(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chrX:44929527-44929528(+) m6A 3'UTR//CDS       22608085 chrX:44970669-44970670(+) m6A 3'UTR       24981863//22608085 chrX:44970681-44970682(+) m6A 3'UTR       24981863//22608085 chrX:44970760-44970761(+) m6A 3'UTR       24981863//22608085 chrX:44970834-44970835(+) m6A 3'UTR       24981863//27773535//22608085 chrX:44970906-44970907(+) m6A 3'UTR       24981863//27773535//22608085 chrX:44970924-44970925(+) m6A 3'UTR       24981863//27773535//22608085 chrX:44970939-44970940(+) m6A 3'UTR       24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3121-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	KDM6A	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3121-3p
Interactor2: KDM6A

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.