Basic Information:

  VIRBase ID:  

HHID00071996

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:  MIMAT0014983          FOXN2:  NR_164691     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-3121-3p	FOXN2
miRBase Accession/Entrez ID	MIMAT0014983	3344
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	HTLF

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-3121-3p	rs1006143795 chr1:180438334    T/C rs778817728 chr1:180438323    T/C rs887772082 chr1:180438327    C/T rs911596096 chr1:180438331    G/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FOXN2	chr2:48602197(+) A-I      NonSyn:Tyr->Cys chr2:48588454(+) A-I      intronic chr2:48588449(+) A-I      intronic chr2:48588453(+) A-I      intronic chr2:48588474(+) A-I      intronic chr2:48581530(+) A-I      intronic chr2:48574532(+) A-I      intronic chr2:48576258(+) A-I      intronic chr2:48547610(+) A-I      intronic chr2:48547569(+) A-I      intronic chr2:48547566(+) A-I      intronic chr2:48547559(+) A-I      intronic chr2:48547557(+) A-I      intronic chr2:48544846(+) A-I      intronic chr2:48544349(+) A-I      intronic chr2:48547627(+) A-I      intronic chr2:48548494(+) A-I      intronic chr2:48546879(+) A-I      intronic chr2:48548496(+) A-I      intronic chr2:48549162(+) A-I      intronic chr2:48549181(+) A-I      intronic chr2:48549250(+) A-I      intronic chr2:48549270(+) A-I      intronic chr2:48578275(+) A-I      intronic chr2:48578290(+) A-I      intronic chr2:48578336(+) A-I      intronic chr2:48581585(+) A-I      intronic chr2:48581592(+) A-I      intronic chr2:48546850(+) A-I      intronic chr2:48544956(+) A-I      intronic chr2:48544410(+) A-I      intronic chr2:48584853(+) A-I      intronic chr2:48586472(+) A-I      intronic chr2:48586559(+) A-I      intronic chr2:48586569(+) A-I      intronic chr2:48586598(+) A-I      intronic chr2:48587993(+) A-I      intronic chr2:48589480(+) A-I      intronic chr2:48589652(+) A-I      intronic chr2:48595082(+) A-I      intronic chr2:48596602(+) A-I      intronic chr2:48546867(+) A-I      intronic chr2:48548420(+) A-I      intronic chr2:48547691(+) A-I      intronic chr2:48595162(+) A-I      intronic chr2:48595788(+) A-I      intronic chr2:48544847(+) A-I      intronic chr2:48588420(+) A-I      intronic chr2:48548511(+) A-I      intronic chr2:48574640(+) A-I      intronic chr2:48576476(+) A-I      intronic chr2:48595131(+) A-I      intronic chr2:48549361(+) A-I      intronic chr2:48548554(+) A-I      intronic chr2:48595684(+) A-I      intronic chr2:48583185(+) A-I      intronic chr2:48578204(+) A-I      intronic chr2:48547006(+) A-I      intronic chr2:48549214(+) A-I      intronic chr2:48574419(+) A-I      intronic chr2:48595062(+) A-I      intronic chr2:48588343(+) A-I      intronic chr2:48586562(+) A-I      intronic chr2:48548495(+) A-I      intronic chr2:48583453(+) A-I      intronic chr2:48544417(+) A-I      intronic chr2:48595107(+) A-I      intronic chr2:48547530(+) A-I      intronic chr2:48548560(+) A-I      intronic chr2:48553168(+) A-I      intronic chr2:48586491(+) A-I      intronic chr2:48589463(+) A-I      intronic chr2:48576475(+) A-I      intronic chr2:48544508(+) A-I      intronic chr2:48596621(+) A-I      intronic chr2:48595183(+) A-I      intronic chr2:48544409(+) A-I      intronic chr2:48576369(+) A-I      intronic chr2:48584710(+) A-I      intronic chr2:48588019(+) A-I      intronic chr2:48596562(+) A-I      intronic chr2:48581751(+) A-I      intronic chr2:48586532(+) A-I      intronic chr2:48586566(+) A-I      intronic chr2:48548486(+) A-I      intronic chr2:48576528(+) A-I      intronic chr2:48584705(+) A-I      intronic chr2:48595603(+) A-I      intronic chr2:48576817(+) A-I      intronic chr2:48564537(+) A-I      intronic chr2:48587987(+) A-I      intronic chr2:48584798(+) A-I      intronic chr2:48588001(+) A-I      intronic chr2:48549188(+) A-I      intronic chr2:48574496(+) A-I      intronic chr2:48549349(+) A-I      intronic chr2:48595558(+) A-I      intronic chr2:48544930(+) A-I      intronic chr2:48574643(+) A-I      intronic chr2:48547620(+) A-I      intronic chr2:48584843(+) A-I      intronic chr2:48576469(+) A-I      intronic chr2:48544333(+) A-I      intronic chr2:48544423(+) A-I      intronic chr2:48596422(+) A-I      intronic chr2:48544927(+) A-I      intronic chr2:48595147(+) A-I      intronic chr2:48578212(+) A-I      intronic chr2:48548512(+) A-I      intronic chr2:48548510(+) A-I      intronic chr2:48593331(+) A-I      intronic chr2:48596662(+) A-I      intronic chr2:48597040(+) A-I      intronic chr2:48595666(+) A-I      intronic chr2:48547664(+) A-I      intronic chr2:48549141(+) A-I      intronic chr2:48583460(+) A-I      intronic chr2:48595139(+) A-I      intronic chr2:48547630(+) A-I      intronic chr2:48581486(+) A-I      intronic chr2:48589574(+) A-I      intronic chr2:48584814(+) A-I      intronic chr2:48544232(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FOXN2	chr2:48605947(+) A-C intron -    21725310 chr2:48544333(+) A-G intron -    22484847 chr2:48544417(+) A-G intron -    22484847 chr2:48544508(+) A-G intron -    22484847 chr2:48544847(+) A-G intron -    22484847 chr2:48544864(+) A-G intron -    22484847 chr2:48544927(+) A-G intron -    22484847 chr2:48544930(+) A-G intron -    22484847 chr2:48544944(+) A-G intron -    22484847 chr2:48546771(+) G-T intron -    22484847 chr2:48547499(+) A-G intron -    22484847 chr2:48547530(+) A-G intron -    22484847 chr2:48547563(+) A-G intron -    22484847 chr2:48547620(+) A-G intron -    22484847 chr2:48547630(+) A-G intron -    22484847 chr2:48547664(+) A-G intron -    22484847 chr2:48548486(+) A-G intron -    22484847 chr2:48548495(+) A-G intron -    22484847 chr2:48548510(+) A-G intron -    22484847 chr2:48548511(+) A-G intron -    22484847 chr2:48548560(+) A-G intron -    22484847 chr2:48549188(+) A-G intron -    22484847 chr2:48551352(+) G-T intron -    22484847 chr2:48551354(+) G-T intron -    22484847 chr2:48563557(+) A-T intron -    22484847 chr2:48564447(+) A-T intron -    22484847 chr2:48583460(+) A-G intron -    22484847 chr2:48586491(+) A-G intron -    22484847 chr2:48586562(+) A-G intron -    22484847 chr2:48586566(+) A-G intron -    22484847 chr2:48586613(+) A-G intron -    22484847 chr2:48589463(+) A-G intron -    22484847 chr2:48595043(+) A-G intron -    22484847 chr2:48595056(+) A-G intron -    22484847 chr2:48595062(+) A-G intron -    22484847 chr2:48595107(+) A-G intron -    22484847 chr2:48595139(+) A-G intron -    22484847 chr2:48595147(+) A-G intron -    22484847 chr2:48595162(+) A-G intron -    22484847 chr2:48595183(+) A-G intron -    22484847 chr2:48595558(+) A-G intron -    22484847 chr2:48595559(+) A-G intron -    22484847 chr2:48595602(+) A-G intron -    22484847 chr2:48595603(+) A-G intron -    22484847 chr2:48595670(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FOXN2	chr2:48541886-48541887(+) m6A 5'UTR       - chr2:48555723-48555724(+) m6A 5'UTR//intron       24284625 chr2:48555765-48555766(+) m6A 5'UTR//intron       - chr2:48555770-48555771(+) m6A 5'UTR//intron       - chr2:48573395-48573396(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:48573495-48573496(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:48573517-48573518(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:48573525-48573526(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:48573531-48573532(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:48573564-48573565(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:48573643-48573644(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:48573660-48573661(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr2:48573783-48573784(+) m6A CDS       24284625//24981863//22608085 chr2:48602376-48602377(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:48602446-48602447(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:48602552-48602553(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:48602648-48602649(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085 chr2:48602701-48602702(+) m6A 3'UTR       24981863//26404942//22608085 chr2:48602737-48602738(+) m6A 3'UTR       24981863//26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-3121-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	FOXN2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-3121-3p
Interactor2: FOXN2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.