Detail Information

Basic Information:


  VIRBase ID:  

HHID00071984

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3121-3p:           CD74:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3121-3p CD74
miRBase
Accession/Entrez ID
MIMAT0014983 972
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DHLAG//HLADG//Ia-GAMMA//II//p33

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3121-3p
rs1006143795 chr1:180438334    T/C
rs778817728 chr1:180438323    T/C
rs887772082 chr1:180438327    C/T
rs911596096 chr1:180438331    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CD74
chr5:149787478(-) A-I      intronic
chr5:149787428(-) A-I      intronic
chr5:149787417(-) A-I      intronic
chr5:149787415(-) A-I      intronic
chr5:149787414(-) A-I      intronic
chr5:149787409(-) A-I      intronic
chr5:149789156(-) A-I      intronic
chr5:149787389(-) A-I      intronic
chr5:149789180(-) A-I      intronic
chr5:149787514(-) A-I      intronic
chr5:149789222(-) A-I      intronic
chr5:149787384(-) A-I      intronic
chr5:149787352(-) A-I      intronic
chr5:149789237(-) A-I      intronic
chr5:149789250(-) A-I      intronic
chr5:149787513(-) A-I      intronic
chr5:149787495(-) A-I      intronic
chr5:149787490(-) A-I      intronic
chr5:149787489(-) A-I      intronic
chr5:149787482(-) A-I      intronic
chr5:149785517(-) A-I      intronic
chr5:149788674(-) A-I      intronic
chr5:149788704(-) A-I      intronic
chr5:149785533(-) A-I      intronic
chr5:149785496(-) A-I      intronic
chr5:149788638(-) A-I      intronic
chr5:149787446(-) A-I      intronic
chr5:149789174(-) A-I      intronic
chr5:149789144(-) A-I      intronic
chr5:149788664(-) A-I      intronic
chr5:149788526(-) A-I      intronic
chr5:149785421(-) A-I      intronic
chr5:149788637(-) A-I      intronic
chr5:149785580(-) A-I      intronic
chr5:149785515(-) A-I      intronic
chr5:149783179(-) A-I      intronic
chr5:149787450(-) A-I      intronic
chr5:149785576(-) A-I      intronic
chr5:149783416(-) A-I      intronic
chr5:149789038(-) A-I      intronic
chr5:149787578(-) A-I      intronic
chr5:149785426(-) A-I      intronic
chr5:149789173(-) A-I      intronic
chr5:149788627(-) A-I      intronic
chr5:149788703(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CD74
chr5:149783346(-) G-A intron -    22484847
chr5:149783416(-) A-G intron -    22484847
chr5:149785496(-) A-G intron -    22484847
chr5:149785515(-) A-G intron -    22484847
chr5:149785633(-) G-C intron -    22484847
chr5:149787382(-) A-G intron -    22484847
chr5:149787403(-) T-C intron -    22484847
chr5:149787446(-) A-G intron -    22484847
chr5:149787456(-) A-G intron -    22484847
chr5:149787493(-) A-G intron -    22484847
chr5:149787578(-) A-G intron -    22484847
chr5:149788571(-) G-A intron -    22484847
chr5:149788611(-) G-A intron -    22484847
chr5:149788664(-) A-G intron -    22484847
chr5:149788703(-) A-G intron -    22484847
chr5:149788704(-) A-G intron -    22484847
chr5:149788744(-) A-G intron -    22484847
chr5:149788795(-) T-C intron -    22484847
chr5:149789038(-) A-G intron -    22484847
chr5:149789100(-) C-T intron -    22484847
chr5:149789134(-) A-G intron -    22484847
chr5:149789144(-) A-G intron -    22484847
chr5:149789173(-) A-G intron -    22484847
chr5:149789174(-) A-G intron -    22484847
chr5:149789262(-) G-T intron -    22484847
chr5:149789264(-) A-T intron -    22484847
chr5:149789267(-) G-T intron -    22484847
chr5:149791583(-) T-C intron -    22484847
chr5:149791646(-) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CD74
chr5:149781428-149781429(-) m6A 3'UTR       25456834//24981863//27371828
chr5:149781440-149781441(-) m6A 3'UTR       25456834//24981863//26404942//27371828
chr5:149781498-149781499(-) m6A 3'UTR       25456834//24981863//26404942//27371828
chr5:149781548-149781549(-) m6A 3'UTR       25456834//26404942//27371828
chr5:149781636-149781637(-) m6A 3'UTR//intron       27371828
chr5:149781651-149781652(-) m6A 3'UTR//intron       27371828
chr5:149781656-149781657(-) m6A 3'UTR//intron       27371828
chr5:149781688-149781689(-) m6A 3'UTR//intron       27371828
chr5:149781859-149781860(-) m6A 3'UTR//intron       27371828
chr5:149781907-149781908(-) m6A 3'UTR//intron       27371828
chr5:149781934-149781935(-) m6A 3'UTR//intron       27371828
chr5:149781987-149781988(-) m6A 3'UTR//intron       -
chr5:149785089-149785090(-) m6A 3'UTR//intron       28052920//27371828
chr5:149785150-149785151(-) m6A 3'UTR//intron       -
chr5:149785193-149785194(-) m6A 3'UTR//intron       -
chr5:149785549-149785550(-) m6A exon//intron       -
chr5:149786737-149786738(-) m6A CDS//exon//intron       27371828
chr5:149786752-149786753(-) m6A CDS//exon//intron       27371828
chr5:149786776-149786777(-) m6A CDS//exon//intron       27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3121-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
CD74
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3121-3p
Interactor2: CD74

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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