Basic Information:

  VIRBase ID:  

HHID00071946

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-2278:  MIMAT0011778          ABT1:  NM_013375     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-2278	ABT1
miRBase Accession/Entrez ID	MIMAT0011778	29777
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	Esf2//hABT1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-2278	rs377343613 chr9:94809995    C/T rs938124353 chr9:94809994    C/T rs991003784 chr9:94809996    T/C rs1229108324 chr9:94809984    G/C rs1229108324 chr9:94809984    G/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ABT1	chr6:26598684(+) A-I      Syn:Thr->Thr

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ABT1	chr6:26597264-26597265(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr6:26597269-26597270(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr6:26597310-26597311(+) m1A CDS       26863196//26863410 chr6:26598210-26598211(+) m6A CDS       24284625 chr6:26598330-26598331(+) m6A CDS       24284625 chr6:26598597-26598598(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598629-26598630(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598655-26598656(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598681-26598682(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598710-26598711(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598775-26598776(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598848-26598849(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598865-26598866(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598957-26598958(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr6:26598978-26598979(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr6:26599002-26599003(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr6:26599040-26599041(+) m6A 3'UTR       24284625//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-2278	Exosome Breast cancer cell lines (MCF-7|MDA-MB-231)     24468161 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	ABT1	Exosome Blood     - Nucleolus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-2278
Interactor2: ABT1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.