Basic Information:

  VIRBase ID:  

HHID00071620

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-2110:  MIMAT0010133          MFSD14A:  NM_033055     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-2110	MFSD14A
miRBase Accession/Entrez ID	MIMAT0010133	64645
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	HIAT1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-2110	rs114530801 chr10:114174163    G/A rs114530801 chr10:114174163    G/C rs114530801 chr10:114174163    G/T rs1168982220 chr10:114174162    C/G rs1188283086 chr10:114174156    A/T rs1246581316 chr10:114174158    C/T rs1412803607 chr10:114174164    T/A rs1431021422 chr10:114174157    G/C rs1476834649 chr10:114174154    TCAG/T rs192664871 chr10:114174154    T/C rs192664871 chr10:114174154    T/G rs573692968 chr10:114174159    G/A rs573692968 chr10:114174159    G/C rs755562830 chr10:114174148    CCTCA/C rs1178383827 chr10:114174165    T/G rs1418383763 chr10:114174167    C/T rs1434681640 chr10:114174169    C/T rs745914474 chr10:114174166    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MFSD14A	chr1:100516483(+) A-I      intronic chr1:100542990(+) A-I      intronic chr1:100540363(+) A-I      intronic chr1:100540343(+) A-I      intronic chr1:100540341(+) A-I      intronic chr1:100540340(+) A-I      intronic chr1:100540320(+) A-I      intronic chr1:100516512(+) A-I      intronic chr1:100516489(+) A-I      intronic chr1:100507392(+) A-I      intronic chr1:100507382(+) A-I      intronic chr1:100541364(+) A-I      intronic chr1:100508305(+) A-I      intronic chr1:100539916(+) A-I      intronic chr1:100540014(+) A-I      intronic chr1:100532900(+) A-I      intronic chr1:100541376(+) A-I      intronic chr1:100532942(+) A-I      intronic chr1:100533105(+) A-I      intronic chr1:100533286(+) A-I      intronic chr1:100540004(+) A-I      intronic chr1:100541314(+) A-I      intronic chr1:100541309(+) A-I      intronic chr1:100540396(+) A-I      intronic chr1:100539954(+) A-I      intronic chr1:100534319(+) A-I      intronic chr1:100540381(+) A-I      intronic chr1:100540282(+) A-I      intronic chr1:100506081(+) A-I      intronic chr1:100506146(+) A-I      intronic chr1:100507225(+) A-I      intronic chr1:100507241(+) A-I      intronic chr1:100540268(+) A-I      intronic chr1:100534337(+) A-I      intronic chr1:100507281(+) A-I      intronic chr1:100507386(+) A-I      intronic chr1:100539875(+) A-I      intronic chr1:100516542(+) A-I      intronic chr1:100539876(+) A-I      intronic chr1:100507469(+) A-I      intronic chr1:100541399(+) A-I      intronic chr1:100508238(+) A-I      intronic chr1:100523076(+) A-I      intronic chr1:100529166(+) A-I      intronic chr1:100529170(+) A-I      intronic chr1:100541496(+) A-I      intronic chr1:100508325(+) A-I      intronic chr1:100516788(+) A-I      intronic chr1:100529267(+) A-I      intronic chr1:100508276(+) A-I      intronic chr1:100529862(+) A-I      intronic chr1:100523091(+) A-I      intronic chr1:100532290(+) A-I      intronic chr1:100516601(+) A-I      intronic chr1:100532464(+) A-I      intronic chr1:100529717(+) A-I      intronic chr1:100532831(+) A-I      intronic chr1:100507395(+) A-I      intronic chr1:100507359(+) A-I      intronic chr1:100532398(+) A-I      intronic chr1:100540015(+) A-I      intronic chr1:100523153(+) A-I      intronic chr1:100529151(+) A-I      intronic chr1:100529798(+) A-I      intronic chr1:100541400(+) A-I      intronic chr1:100522980(+) A-I      intronic chr1:100522972(+) A-I      intronic chr1:100508303(+) A-I      intronic chr1:100506134(+) A-I      intronic chr1:100508220(+) A-I      intronic chr1:100532291(+) A-I      intronic chr1:100530664(+) A-I      intronic chr1:100540050(+) A-I      intronic chr1:100506033(+) A-I      intronic chr1:100533176(+) A-I      intronic chr1:100507360(+) A-I      intronic chr1:100541454(+) A-I      intronic chr1:100507330(+) A-I      intronic chr1:100541469(+) A-I      intronic chr1:100540281(+) A-I      intronic chr1:100507337(+) A-I      intronic chr1:100519697(+) A-I      intronic chr1:100519791(+) A-I      intronic chr1:100508437(+) A-I      intronic chr1:100522051(+) A-I      intronic chr1:100529947(+) A-I      intronic chr1:100507425(+) A-I      intronic chr1:100530665(+) A-I      intronic chr1:100507327(+) A-I      intronic chr1:100507435(+) A-I      intronic chr1:100516530(+) A-I      intronic chr1:100522116(+) A-I      intronic chr1:100506278(+) A-I      intronic chr1:100508240(+) A-I      intronic chr1:100508395(+) A-I      intronic chr1:100521492(+) A-I      intronic chr1:100508293(+) A-I      intronic chr1:100544761(+) A-I      intronic chr1:100506117(+) A-I      intronic chr1:100506220(+) A-I      intronic chr1:100508349(+) A-I      intronic chr1:100508268(+) A-I      intronic chr1:100540286(+) A-I      intronic chr1:100507224(+) A-I      intronic chr1:100541374(+) A-I      intronic chr1:100507208(+) A-I      intronic chr1:100516462(+) A-I      intronic chr1:100508281(+) A-I      intronic chr1:100507255(+) A-I      intronic chr1:100522115(+) A-I      intronic chr1:100516463(+) A-I      intronic chr1:100508375(+) A-I      intronic chr1:100533222(+) A-I      intronic chr1:100539873(+) A-I      intronic chr1:100541486(+) A-I      intronic chr1:100529888(+) A-I      intronic chr1:100507421(+) A-I      intronic chr1:100519698(+) A-I      intronic chr1:100521378(+) A-I      intronic chr1:100530691(+) A-I      intronic chr1:100522118(+) A-I      intronic chr1:100516520(+) A-I      intronic chr1:100508346(+) A-I      intronic chr1:100529890(+) A-I      intronic chr1:100507329(+) A-I      intronic chr1:100516490(+) A-I      intronic chr1:100507369(+) A-I      intronic chr1:100507333(+) A-I      intronic chr1:100522014(+) A-I      intronic chr1:100508267(+) A-I      intronic chr1:100519653(+) A-I      intronic chr1:100533305(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-2110	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	MFSD14A	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-2110
Interactor2: MFSD14A

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.