Basic Information:

  VIRBase ID:  

HHID00071612

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-2110:  MIMAT0010133          CLCF1:  NM_013246     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-2110	CLCF1
miRBase Accession/Entrez ID	MIMAT0010133	23529
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	BSF-3//BSF3//CISS2//CLC//NNT-1//NNT1//NR6

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-2110	rs114530801 chr10:114174163    G/A rs114530801 chr10:114174163    G/C rs114530801 chr10:114174163    G/T rs1168982220 chr10:114174162    C/G rs1188283086 chr10:114174156    A/T rs1246581316 chr10:114174158    C/T rs1412803607 chr10:114174164    T/A rs1431021422 chr10:114174157    G/C rs1476834649 chr10:114174154    TCAG/T rs192664871 chr10:114174154    T/C rs192664871 chr10:114174154    T/G rs573692968 chr10:114174159    G/A rs573692968 chr10:114174159    G/C rs755562830 chr10:114174148    CCTCA/C rs1178383827 chr10:114174165    T/G rs1418383763 chr10:114174167    C/T rs1434681640 chr10:114174169    C/T rs745914474 chr10:114174166    T/C

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CLCF1	chr11:67131945-67131946(-) m6A 3'UTR       24981863 chr11:67131964-67131965(-) m6A 3'UTR       24981863 chr11:67131969-67131970(-) m6A 3'UTR       25456834//24981863//27773535 chr11:67132000-67132001(-) m6A 3'UTR       24284625//25456834//24981863//27773535 chr11:67132005-67132006(-) m6A 3'UTR       24284625//25456834//24981863//27773535 chr11:67132014-67132015(-) m6A 3'UTR       24284625//25456834//24981863//27773535 chr11:67132050-67132051(-) m6A 3'UTR       24284625//24981863//27773535 chr11:67132131-67132132(-) m6A 3'UTR       27773535 chr11:67132482-67132483(-) m6A 3'UTR       27773535 chr11:67132514-67132515(-) m6A 3'UTR       24284625//24981863//27773535 chr11:67132572-67132573(-) m6A 3'UTR       24284625//25456834//24981863//27773535//27371828 chr11:67132682-67132683(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67132707-67132708(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67132776-67132777(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67132786-67132787(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67132791-67132792(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67132967-67132968(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67132984-67132985(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67133037-67133038(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67133066-67133067(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960 chr11:67133096-67133097(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960 chr11:67134935-67134936(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960 chr11:67134986-67134987(-) m6A CDS       24284625//24209618//24981863//27773535 chr11:67135015-67135016(-) m6A CDS       24284625//24209618//27773535 chr11:67135093-67135094(-) m6A 5'UTR//CDS       24209618 chr11:67141005-67141006(-) m6A CDS//intron       24209618//27773536 chr11:67141127-67141128(-) m6A 5'UTR//intron       24981863//27773535 chr11:67141141-67141142(-) m6A 5'UTR//intron       24981863//27773535 chr11:67141533-67141534(-) m6A 5'UTR       24981863//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-2110	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	CLCF1	Chromatin K562 cells     - Exosome Blood     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-2110
Interactor2: CLCF1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.