Detail Information

Basic Information:


  VIRBase ID:  

HHID00071591

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-2110:           IL2RG:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-2110 IL2RG
miRBase
Accession/Entrez ID		 MIMAT0010133 3561
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CD132//CIDX//IL-2RG//IMD4//P64//SCIDX//SCIDX1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-2110
rs114530801 chr10:114174163    G/A
rs114530801 chr10:114174163    G/C
rs114530801 chr10:114174163    G/T
rs1168982220 chr10:114174162    C/G
rs1188283086 chr10:114174156    A/T
rs1246581316 chr10:114174158    C/T
rs1412803607 chr10:114174164    T/A
rs1431021422 chr10:114174157    G/C
rs1476834649 chr10:114174154    TCAG/T
rs192664871 chr10:114174154    T/C
rs192664871 chr10:114174154    T/G
rs573692968 chr10:114174159    G/A
rs573692968 chr10:114174159    G/C
rs755562830 chr10:114174148    CCTCA/C
rs1178383827 chr10:114174165    T/G
rs1418383763 chr10:114174167    C/T
rs1434681640 chr10:114174169    C/T
rs745914474 chr10:114174166    T/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IL2RG
chrX:70327292-70327293(-) m6A 3'UTR//exon       28052920//27773535
chrX:70327398-70327399(-) m6A 3'UTR//exon       28052920//27773535
chrX:70327562-70327563(-) m6A 3'UTR//exon       26404942//27773535
chrX:70327584-70327585(-) m6A 3'UTR//exon       26404942//27773535
chrX:70327590-70327591(-) m6A 3'UTR//CDS//exon       26404942//27773535
chrX:70327962-70327963(-) m6A exon//intron       27371828
chrX:70327977-70327978(-) m6A exon//intron       27371828
chrX:70328066-70328067(-) m6A exon//intron       -
chrX:70329237-70329238(-) m6A 5'UTR//CDS//exon       26404942
chrX:70330007-70330008(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330018-70330019(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330028-70330029(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330060-70330061(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330075-70330076(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330081-70330082(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330086-70330087(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330107-70330108(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330123-70330124(-) m6A 5'UTR//CDS//exon//intron       26404942
chrX:70330980-70330981(-) m6A 5'UTR//exon//intron       27773535//27371828
chrX:70331259-70331260(-) m6A 5'UTR//CDS//exon//intron       27371828
chrX:70331285-70331286(-) m6A 5'UTR//CDS//exon       26404942//27371828
chrX:70331318-70331319(-) m6A 5'UTR//CDS//exon       28052920//26404942//27371828
chrX:70331422-70331423(-) m6A 5'UTR//exon//intron       28052920//26404942//27371828
chrX:70331441-70331442(-) m6A 5'UTR//exon//intron       28052920//26404942//27371828
chrX:70331944-70331945(-) m6A 5'UTR       27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-2110
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Extracellular vesicle HEK-293T cells     22849433
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
IL2RG
Cytosol K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-2110
Interactor2: IL2RG

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

Starting a new search, please wait ...