Detail Information

Basic Information:


  VIRBase ID:  

HHID00071589

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-2110:           ESD:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-2110 ESD
miRBase
Accession/Entrez ID		 MIMAT0010133 2098
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - FGH

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-2110
rs114530801 chr10:114174163    G/A
rs114530801 chr10:114174163    G/C
rs114530801 chr10:114174163    G/T
rs1168982220 chr10:114174162    C/G
rs1188283086 chr10:114174156    A/T
rs1246581316 chr10:114174158    C/T
rs1412803607 chr10:114174164    T/A
rs1431021422 chr10:114174157    G/C
rs1476834649 chr10:114174154    TCAG/T
rs192664871 chr10:114174154    T/C
rs192664871 chr10:114174154    T/G
rs573692968 chr10:114174159    G/A
rs573692968 chr10:114174159    G/C
rs755562830 chr10:114174148    CCTCA/C
rs1178383827 chr10:114174165    T/G
rs1418383763 chr10:114174167    C/T
rs1434681640 chr10:114174169    C/T
rs745914474 chr10:114174166    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ESD
chr13:47368535(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ESD
chr13:47345577-47345578(-) m6A CDS       27773535
chr13:47361237-47361238(-) m6A 5'UTR//CDS//exon       27773535
chr13:47364763-47364764(-) m6A 5'UTR//intron       27773535
chr13:47365488-47365489(-) m6A 5'UTR//CDS//exon       24284625//27773535
chr13:47367534-47367535(-) m6A 5'UTR//exon       24284625//24981863//27773535//22608085
chr13:47371348-47371349(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-2110
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Extracellular vesicle HEK-293T cells     22849433
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
ESD
Chromatin K562 cells     -
Exosome Blood     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-2110
Interactor2: ESD

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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