Basic Information:

  VIRBase ID:  

HHID00071587

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-2110:  MIMAT0010133          CSNK1G2:  NM_001319     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-2110	CSNK1G2
miRBase Accession/Entrez ID	MIMAT0010133	1455
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CK1g2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-2110	rs114530801 chr10:114174163    G/A rs114530801 chr10:114174163    G/C rs114530801 chr10:114174163    G/T rs1168982220 chr10:114174162    C/G rs1188283086 chr10:114174156    A/T rs1246581316 chr10:114174158    C/T rs1412803607 chr10:114174164    T/A rs1431021422 chr10:114174157    G/C rs1476834649 chr10:114174154    TCAG/T rs192664871 chr10:114174154    T/C rs192664871 chr10:114174154    T/G rs573692968 chr10:114174159    G/A rs573692968 chr10:114174159    G/C rs755562830 chr10:114174148    CCTCA/C rs1178383827 chr10:114174165    T/G rs1418383763 chr10:114174167    C/T rs1434681640 chr10:114174169    C/T rs745914474 chr10:114174166    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CSNK1G2	chr19:1965922(+) A-I      intronic chr19:1947005(+) A-I      intronic chr19:1945606(+) A-I      intronic chr19:1945028(+) A-I      intronic chr19:1945559(+) A-I      intronic chr19:1945650(+) A-I      intronic chr19:1952461(+) A-I      intronic chr19:1945700(+) A-I      intronic chr19:1945710(+) A-I      intronic chr19:1946395(+) A-I      intronic chr19:1946430(+) A-I      intronic chr19:1946432(+) A-I      intronic chr19:1946466(+) A-I      intronic chr19:1946475(+) A-I      intronic chr19:1946489(+) A-I      intronic chr19:1946777(+) A-I      intronic chr19:1946778(+) A-I      intronic chr19:1946809(+) A-I      intronic chr19:1946817(+) A-I      intronic chr19:1976794(+) A-I      intronic chr19:1952401(+) A-I      intronic chr19:1952439(+) A-I      intronic chr19:1952451(+) A-I      intronic chr19:1946497(+) A-I      intronic chr19:1960629(+) A-I      intronic chr19:1960637(+) A-I      intronic chr19:1960648(+) A-I      intronic chr19:1960654(+) A-I      intronic chr19:1976813(+) A-I      intronic chr19:1976918(+) A-I      intronic chr19:1976990(+) A-I      intronic chr19:1977731(+) A-I      intronic chr19:1945660(+) A-I      intronic chr19:1962187(+) A-I      intronic chr19:1963340(+) A-I      intronic chr19:1963402(+) A-I      intronic chr19:1963471(+) A-I      intronic chr19:1963472(+) A-I      intronic chr19:1963473(+) A-I      intronic chr19:1963485(+) A-I      intronic chr19:1963600(+) A-I      intronic chr19:1963687(+) A-I      intronic chr19:1965539(+) A-I      intronic chr19:1965236(+) A-I      intronic chr19:1965229(+) A-I      intronic chr19:1965225(+) A-I      intronic chr19:1964874(+) A-I      intronic chr19:1964236(+) A-I      intronic chr19:1963690(+) A-I      intronic chr19:1966050(+) A-I      intronic chr19:1964237(+) A-I      intronic chr19:1965001(+) A-I      intronic chr19:1945770(+) A-I      intronic chr19:1945611(+) A-I      intronic chr19:1962619(+) A-I      intronic chr19:1977631(+) A-I      intronic chr19:1964961(+) A-I      intronic chr19:1977600(+) A-I      intronic chr19:1945661(+) A-I      intronic chr19:1977602(+) A-I      intronic chr19:1965937(+) A-I      intronic chr19:1962571(+) A-I      intronic chr19:1965672(+) A-I      intronic chr19:1976816(+) A-I      intronic chr19:1977574(+) A-I      intronic chr19:1962210(+) A-I      intronic chr19:1965661(+) A-I      intronic chr19:1952502(+) A-I      intronic chr19:1964745(+) A-I      intronic chr19:1976843(+) A-I      intronic chr19:1976972(+) A-I      intronic chr19:1963606(+) A-I      intronic chr19:1977715(+) A-I      intronic chr19:1965929(+) A-I      intronic chr19:1966906(+) A-I      intronic chr19:1963270(+) A-I      intronic chr19:1962251(+) A-I      intronic chr19:1945786(+) A-I      intronic chr19:1976819(+) A-I      intronic chr19:1964805(+) A-I      intronic chr19:1948461(+) A-I      intronic chr19:1964171(+) A-I      intronic chr19:1977575(+) A-I      intronic chr19:1946741(+) A-I      intronic chr19:1946309(+) A-I      intronic chr19:1965228(+) A-I      intronic chr19:1964842(+) A-I      intronic chr19:1962143(+) A-I      intronic chr19:1964217(+) A-I      intronic chr19:1976884(+) A-I      intronic chr19:1965561(+) A-I      intronic chr19:1977527(+) A-I      intronic chr19:1976868(+) A-I      intronic chr19:1977596(+) A-I      intronic chr19:1977625(+) A-I      intronic chr19:1945766(+) A-I      intronic chr19:1976878(+) A-I      intronic chr19:1963636(+) A-I      intronic chr19:1977542(+) A-I      intronic chr19:1965987(+) A-I      intronic chr19:1976905(+) A-I      intronic chr19:1976904(+) A-I      intronic chr19:1964985(+) A-I      intronic chr19:1960632(+) A-I      intronic chr19:1962269(+) A-I      intronic chr19:1964207(+) A-I      intronic chr19:1962501(+) A-I      intronic chr19:1964764(+) A-I      intronic chr19:1963607(+) A-I      intronic chr19:1965558(+) A-I      intronic chr19:1965815(+) A-I      intronic chr19:1977672(+) A-I      intronic chr19:1964886(+) A-I      intronic chr19:1976795(+) A-I      intronic chr19:1964854(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CSNK1G2	chr19:1946999(+) T-C intron -    22484847 chr19:1962210(+) A-G intron -    22484847 chr19:1962408(+) A-G intron -    22484847 chr19:1976795(+) A-G intron -    22484847 chr19:1976972(+) A-G intron -    22484847 chr19:1977672(+) A-G intron -    22484847 chr19:1977698(+) A-G intron -    22484847 chr19:1977715(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CSNK1G2	chr19:1941248-1941249(+) m6A 5'UTR//exon       27773536 chr19:1942535-1942536(+) m6A 5'UTR//intron       24284625 chr19:1968892-1968893(+) m6A 5'UTR//intron       24284625//24209618 chr19:1969697-1969698(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:1969714-1969715(+) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr19:1969767-1969768(+) m6A 5'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr19:1969873-1969874(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr19:1974723-1974724(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960 chr19:1978684-1978685(+) m6A CDS//exon       24284625 chr19:1978707-1978708(+) m6A CDS//exon       24284625 chr19:1978918-1978919(+) m6A CDS//exon       24284625//22575960 chr19:1978941-1978942(+) m6A CDS//exon       24284625//24981863//22575960 chr19:1979007-1979008(+) m6A CDS//exon       24284625//24981863//26404942//22575960 chr19:1979129-1979130(+) m6A exon//intron       24284625 chr19:1979307-1979308(+) m6A exon//intron       24284625 chr19:1979354-1979355(+) m6A CDS//exon       24284625 chr19:1979393-1979394(+) m6A CDS//exon       24284625 chr19:1979532-1979533(+) m6A CDS//exon       24284625 chr19:1979805-1979806(+) m6A CDS//exon       24284625 chr19:1979810-1979811(+) m6A CDS//exon       24284625 chr19:1979829-1979830(+) m6A CDS//exon       24284625 chr19:1979850-1979851(+) m6A exon//intron       24284625 chr19:1979916-1979917(+) m6A CDS//exon       24284625 chr19:1980011-1980012(+) m6A CDS//exon       24284625//24209618 chr19:1980302-1980303(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr19:1980327-1980328(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr19:1980395-1980396(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:1980458-1980459(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:1980481-1980482(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:1980707-1980708(+) m6A 3'UTR       24284625//24209618 chr19:1980754-1980755(+) m6A 3'UTR       24284625//24209618 chr19:1980904-1980905(+) Y 3'UTR       26075521 chr19:1980949-1980950(+) m6A 3'UTR       24284625//24209618 chr19:1980964-1980965(+) m6A 3'UTR       24284625//24209618 chr19:1981066-1981067(+) m6A 3'UTR       24284625//25456834//24981863 chr19:1981133-1981134(+) m6A 3'UTR       24284625//25456834//24981863 chr19:1981331-1981332(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-2110	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	CSNK1G2	Chromatin K562 cells     - Cytosol HeLa-S3 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-2110
Interactor2: CSNK1G2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.