Detail Information

Basic Information:


  VIRBase ID:  

HHID00071386

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365a-5p:           MS4A1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365a-5p MS4A1
miRBase
Accession/Entrez ID		 MIMAT0009199 931
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - B1//Bp35//CD20//CVID5//FMC7//LEU-16//MS4A2//S7

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365a-5p
rs1166908611 chr16:14309308    T/C
rs1368596991 chr16:14309314    G/A
rs1380926089 chr16:14309318    A/G
rs1396179427 chr16:14309310    G/C
rs1428928383 chr16:14309320    G/A
rs773834113 chr16:14309301    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MS4A1
chr11:60229198(+) A-I      intronic
chr11:60227509(+) A-I      intronic
chr11:60229134(+) A-I      intronic
chr11:60227518(+) A-I      intronic
chr11:60229254(+) A-I      intronic
chr11:60229092(+) A-I      intronic
chr11:60227517(+) A-I      intronic
chr11:60229093(+) A-I      intronic
chr11:60229024(+) A-I      intronic
chr11:60227523(+) A-I      intronic
chr11:60224347(+) A-I      intronic
chr11:60229202(+) A-I      intronic
chr11:60229213(+) A-I      intronic
chr11:60229073(+) A-I      intronic
chr11:60229012(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MS4A1
chr11:60224347(+) A-G intron -    22484847
chr11:60227509(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MS4A1
chr11:60235757-60235758(+) m6A CDS//exon       -
chr11:60235800-60235801(+) m6A CDS//exon       -
chr11:60235828-60235829(+) m6A CDS       -
chr11:60235869-60235870(+) m6A CDS       -
chr11:60235879-60235880(+) m6A CDS       -
chr11:60235889-60235890(+) m6A CDS       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365a-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
MS4A1
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365a-5p
Interactor2: MS4A1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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