Detail Information

Basic Information:


  VIRBase ID:  

HHID00071380

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365a-5p:           AMFR:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365a-5p AMFR
miRBase
Accession/Entrez ID		 MIMAT0009199 267
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GP78//RNF45

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365a-5p
rs1166908611 chr16:14309308    T/C
rs1368596991 chr16:14309314    G/A
rs1380926089 chr16:14309318    A/G
rs1396179427 chr16:14309310    G/C
rs1428928383 chr16:14309320    G/A
rs773834113 chr16:14309301    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR AMFR
chr16:56454970(-) A-I      intronic
chr16:56454959(-) A-I      intronic
chr16:56454938(-) A-I      intronic
chr16:56454981(-) A-I      intronic
chr16:56454982(-) A-I      intronic
chr16:56454975(-) A-I      intronic
chr16:56454960(-) A-I      intronic
chr16:56454949(-) A-I      intronic
chr16:56454889(-) A-I      intronic
chr16:56454971(-) A-I      intronic
chr16:56418960(-) A-I      intronic
chr16:56419033(-) A-I      intronic
chr16:56419124(-) A-I      intronic
chr16:56419345(-) A-I      intronic
chr16:56419462(-) A-I      intronic
chr16:56454760(-) A-I      intronic
chr16:56453539(-) A-I      intronic
chr16:56453525(-) A-I      intronic
chr16:56453226(-) A-I      intronic
chr16:56453118(-) A-I      intronic
chr16:56453018(-) A-I      intronic
chr16:56453004(-) A-I      intronic
chr16:56453000(-) A-I      intronic
chr16:56451130(-) A-I      intronic
chr16:56450548(-) A-I      intronic
chr16:56450463(-) A-I      intronic
chr16:56450455(-) A-I      intronic
chr16:56440407(-) A-I      intronic
chr16:56440360(-) A-I      intronic
chr16:56398680(-) A-I      intronic
chr16:56418803(-) A-I      intronic
chr16:56418819(-) A-I      intronic
chr16:56418882(-) A-I      intronic
chr16:56419336(-) A-I      intronic
chr16:56451318(-) A-I      intronic
chr16:56419145(-) A-I      intronic
chr16:56453620(-) A-I      intronic
chr16:56439805(-) A-I      intronic
chr16:56419407(-) A-I      intronic
chr16:56409943(-) A-I      intronic
chr16:56419044(-) A-I      intronic
chr16:56451275(-) A-I      intronic
chr16:56452608(-) A-I      intronic
chr16:56450367(-) A-I      intronic
chr16:56445287(-) A-I      intronic
chr16:56419150(-) A-I      intronic
chr16:56419284(-) A-I      intronic
chr16:56450600(-) A-I      intronic
chr16:56453214(-) A-I      intronic
chr16:56406706(-) A-I      intronic
chr16:56419488(-) A-I      intronic
chr16:56451955(-) A-I      intronic
chr16:56450461(-) A-I      intronic
chr16:56451336(-) A-I      intronic
chr16:56419436(-) A-I      intronic
chr16:56450509(-) A-I      intronic
chr16:56419437(-) A-I      intronic
chr16:56450635(-) A-I      intronic
chr16:56450522(-) A-I      intronic
chr16:56451272(-) A-I      intronic
chr16:56418811(-) A-I      intronic
chr16:56453448(-) A-I      intronic
chr16:56398771(-) A-I      intronic
chr16:56445403(-) A-I      intronic
chr16:56450495(-) A-I      intronic
chr16:56451332(-) A-I      intronic
chr16:56419362(-) A-I      intronic
chr16:56451328(-) A-I      intronic
chr16:56450447(-) A-I      intronic
chr16:56453442(-) A-I      intronic
chr16:56419432(-) A-I      intronic
chr16:56445363(-) A-I      intronic
chr16:56450434(-) A-I      intronic
chr16:56445217(-) A-I      intronic
chr16:56406895(-) A-I      intronic
chr16:56450454(-) A-I      intronic
chr16:56418930(-) A-I      intronic
chr16:56450547(-) A-I      intronic
chr16:56451857(-) A-I      intronic
chr16:56419424(-) A-I      intronic
chr16:56453623(-) A-I      intronic
chr16:56418825(-) A-I      intronic
chr16:56443892(-) A-I      intronic
chr16:56398697(-) A-I      intronic
chr16:56452048(-) A-I      intronic
chr16:56406349(-) A-I      intronic
chr16:56453606(-) A-I      intronic
chr16:56401924(-) A-I      intronic
chr16:56450469(-) A-I      intronic
chr16:56454933(-) A-I      intronic
chr16:56455317(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED AMFR
chr16:56455317(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AMFR
chr16:56396271-56396272(-) Y 3'UTR//exon       25219674//26075521
chr16:56396565-56396566(-) m6A 3'UTR//exon       24284625//24981863//27773535//22608085
chr16:56396613-56396614(-) m6A 3'UTR//exon       24284625//24981863//28052920//27773535//22608085
chr16:56396677-56396678(-) m6A 3'UTR//exon       24284625//24981863//28052920//27773535//22608085
chr16:56396828-56396829(-) m6A CDS//exon       24284625//24981863
chr16:56396956-56396957(-) m6A CDS//exon       24284625
chr16:56459000-56459001(-) m6A CDS       27773536
chr16:56459038-56459039(-) m6A CDS       27773536
chr16:56459099-56459100(-) m6A CDS       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365a-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
AMFR
Chromatin HCC cell line (HepG2)|K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365a-5p
Interactor2: AMFR

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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