Detail Information

Basic Information:


  VIRBase ID:  

HHID00071364

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-103a-2-5p:           SREK1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-103a-2-5p SREK1
miRBase
Accession/Entrez ID		 MIMAT0009196 140890
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - SFRS12//SRrp508//SRrp86

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-103a-2-5p
rs1315599005 chr20:3917515    A/G
rs1319257633 chr20:3917504    A/G
rs766345821 chr20:3917522    C/T
rs1201044934 chr20:3917509    C/CTG

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SREK1
chr5:65466496(+) A-I      NonSyn:Glu->Gly
chr5:65444552(+) A-I      intronic
chr5:65444953(+) A-I      intronic
chr5:65444926(+) A-I      intronic
chr5:65444573(+) A-I      intronic
chr5:65444944(+) A-I      intronic
chr5:65445205(+) A-I      intronic
chr5:65441850(+) A-I      intronic
chr5:65445018(+) A-I      intronic
chr5:65445054(+) A-I      intronic
chr5:65445034(+) A-I      intronic
chr5:65445019(+) A-I      intronic
chr5:65442877(+) A-I      intronic
chr5:65478555(+) A-I      3'UTR
chr5:65447954(+) A-I      intronic
chr5:65444490(+) A-I      intronic
chr5:65442837(+) A-I      intronic
chr5:65478670(+) A-I      3'UTR
chr5:65444927(+) A-I      intronic
chr5:65462453(+) A-I      intronic
chr5:65444932(+) A-I      intronic
chr5:65444998(+) A-I      intronic
chr5:65447880(+) A-I      intronic
chr5:65442826(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SREK1
chr5:65444490(+) A-G intron -    22484847
chr5:65444927(+) A-G intron -    22484847
chr5:65444932(+) A-G intron -    22484847
chr5:65444998(+) A-G intron -    22484847
chr5:65445061(+) A-G intron -    22484847
chr5:65445095(+) A-G intron -    22484847
chr5:65446869(+) A-G intron -    22484847
chr5:65447880(+) A-G intron -    22484847
chr5:65447884(+) A-G intron -    22484847
chr5:65462516(+) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SREK1
chr5:65457985-65457986(+) m6A 3'UTR//CDS//exon       -
chr5:65460719-65460720(+) m6A 3'UTR//CDS//exon       24981863//27773535
chr5:65465908-65465909(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr5:65465916-65465917(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr5:65466414-65466415(+) m6A 3'UTR//CDS//exon       24284625//25456834//24981863//27773535//27371828//27773536//22608085
chr5:65466426-65466427(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466471-65466472(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466531-65466532(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466537-65466538(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466543-65466544(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466561-65466562(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466573-65466574(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466585-65466586(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466627-65466628(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:65466646-65466647(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:65466651-65466652(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:65466675-65466676(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr5:65466725-65466726(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr5:65470819-65470820(+) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr5:65470828-65470829(+) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr5:65473209-65473210(+) m6A exon//intron       24981863//27773535//22608085
chr5:65473379-65473380(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr5:65473469-65473470(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr5:65474566-65474567(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr5:65474615-65474616(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr5:65474625-65474626(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr5:65474667-65474668(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr5:65474681-65474682(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr5:65474697-65474698(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr5:65474769-65474770(+) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr5:65474874-65474875(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr5:65474903-65474904(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr5:65474978-65474979(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr5:65474997-65474998(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr5:65475031-65475032(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr5:65475209-65475210(+) m6A 3'UTR//exon       24981863//27773535//22608085
chr5:65475264-65475265(+) m6A 3'UTR//exon       24981863//26404942//27773535//22608085
chr5:65475323-65475324(+) m6A 3'UTR//exon       24981863//26404942//22608085
chr5:65475420-65475421(+) m6A 3'UTR//exon       24981863//26404942//22608085
chr5:65476544-65476545(+) m6A 3'UTR//exon       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-103a-2-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
SREK1
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-103a-2-5p
Interactor2: SREK1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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