Detail Information

Basic Information:


  VIRBase ID:  

HHID00071317

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-103a-2-5p:           SNX12:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-103a-2-5p SNX12
miRBase
Accession/Entrez ID		 MIMAT0009196 29934
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-103a-2-5p
rs1315599005 chr20:3917515    A/G
rs1319257633 chr20:3917504    A/G
rs766345821 chr20:3917522    C/T
rs1201044934 chr20:3917509    C/CTG

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SNX12
chrX:70282387(-) A-I      intronic
chrX:70285649(-) A-I      intronic
chrX:70282360(-) A-I      intronic
chrX:70282416(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SNX12
chrX:70280613-70280614(-) m6A 3'UTR//exon//intron       24209618
chrX:70280668-70280669(-) m6A 3'UTR//exon//intron       24209618//24981863
chrX:70280751-70280752(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//22608085
chrX:70280836-70280837(-) Y 3'UTR//exon//intron       26075521
chrX:70280893-70280894(-) m6A CDS//exon//intron       24284625
chrX:70282794-70282795(-) m6A CDS//exon       22575960
chrX:70288103-70288104(-) m6A CDS//exon       27773535//22575960
chrX:70288148-70288149(-) m6A CDS//exon       22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-103a-2-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
SNX12
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-103a-2-5p
Interactor2: SNX12

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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