Basic Information:

  VIRBase ID:  

HHID00071220

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-103a-2-5p:  MIMAT0009196          CPT2:  NM_000098     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-103a-2-5p	CPT2
miRBase Accession/Entrez ID	MIMAT0009196	1376
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CPT1//CPTASE//IIAE4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-103a-2-5p	rs1315599005 chr20:3917515    A/G rs1319257633 chr20:3917504    A/G rs766345821 chr20:3917522    C/T rs1201044934 chr20:3917509    C/CTG

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CPT2	chr1:53677997(+) A-I      intronic chr1:53678009(+) A-I      intronic chr1:53677996(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CPT2	chr1:53679610(+) G-A intron -    22484847 chr1:53678234(+) G-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CPT2	chr1:53662563-53662564(+) m6A 5'UTR//exon       24981863 chr1:53662571-53662572(+) m6A 5'UTR//exon       24981863 chr1:53668042-53668043(+) m6A CDS//exon       24284625 chr1:53668068-53668069(+) m6A CDS//exon       24284625 chr1:53668081-53668082(+) m6A CDS//exon       24284625 chr1:53668203-53668204(+) m6A exon//intron       24284625 chr1:53675719-53675720(+) m6A CDS       24284625//24209618//24981863//22608085 chr1:53675734-53675735(+) m6A CDS       24284625//24209618//24981863//22608085 chr1:53675838-53675839(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:53675881-53675882(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:53675915-53675916(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:53676029-53676030(+) m6A CDS       24284625//24981863//22608085 chr1:53676044-53676045(+) m6A CDS       24284625//22608085 chr1:53676068-53676069(+) m6A CDS       24284625//22608085 chr1:53676130-53676131(+) m6A CDS       24284625//24981863//27773535//22608085 chr1:53676181-53676182(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085 chr1:53676229-53676230(+) m6A CDS       24284625//25456834//24981863//27773535//22608085 chr1:53676235-53676236(+) m6A CDS       24284625//25456834//24981863//27773535//22608085 chr1:53676301-53676302(+) m6A CDS       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr1:53676346-53676347(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr1:53676391-53676392(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr1:53676514-53676515(+) m6A CDS       24284625//24981863//22608085 chr1:53676525-53676526(+) m6A CDS       24284625//24981863//22608085 chr1:53676587-53676588(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:53676618-53676619(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:53676663-53676664(+) m6A CDS       24284625//25456834//24981863//26404942//22575960//22608085 chr1:53676789-53676790(+) m6A CDS       24284625//24981863//22608085 chr1:53676846-53676847(+) m6A CDS       24284625 chr1:53679016-53679017(+) m6A CDS       24284625//24981863//22575960//22608085 chr1:53679037-53679038(+) m6A CDS       24284625//24981863//22608085 chr1:53679082-53679083(+) m6A CDS       24284625//24981863//22608085 chr1:53679518-53679519(+) m6A 3'UTR       24981863 chr1:53679587-53679588(+) m6A 3'UTR       24981863//27773535//22608085 chr1:53679601-53679602(+) m6A 3'UTR       24981863//27773535//22608085 chr1:53679618-53679619(+) m6A 3'UTR       25456834//24981863//27773535//22608085 chr1:53679656-53679657(+) m6A 3'UTR       25456834//24981863//27773535//22608085 chr1:53679741-53679742(+) m6A 3'UTR       27773535//22608085 chr1:53679813-53679814(+) m6A 3'UTR       27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-103a-2-5p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849
	CPT2	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-103a-2-5p
Interactor2: CPT2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.