Detail Information

Basic Information:


  VIRBase ID:  

HHID00071154

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320d:           RAB3IP:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-320d RAB3IP
miRBase
Accession/Entrez ID		 MIMAT0006764 117177
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - RABIN3//RABIN8

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-320d
rs1013069487 chr13:40727828    T/C
rs1212045422 chr13:40727836    ACC/A
rs1287962814 chr13:40727836    A/G
rs755131134 chr13:40727846    T/C
rs757049836 chr13:40727829    C/A
rs757049836 chr13:40727829    C/T
rs772990558 chr13:40727831    T/C
rs1441164440 chrX:140926173    C/G
rs1556096982 chrX:140926178    C/G
rs782742486 chrX:140926174    C/G
rs782742486 chrX:140926174    C/T
rs1371780032 chr13:40727825    TCATCCTCTCAACCCAGC/T
rs535778068 chr13:40727842    C/G
rs569951817 chr13:40727839    C/T
rs1330731340 chrX:140926183    C/G
rs1384057774 chrX:140926185    G/A
rs1422735584 chrX:140926184    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RAB3IP
chr12:70204835(+) A-I      intronic
chr12:70204919(+) A-I      intronic
chr12:70204895(+) A-I      intronic
chr12:70147338(+) A-I      intronic
chr12:70165061(+) A-I      intronic
chr12:70204945(+) A-I      intronic
chr12:70204971(+) A-I      intronic
chr12:70204956(+) A-I      intronic
chr12:70204898(+) A-I      intronic
chr12:70204946(+) A-I      intronic
chr12:70204904(+) A-I      intronic
chr12:70204837(+) A-I      intronic
chr12:70138283(+) A-I      intronic
chr12:70214478(+) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RAB3IP
chr12:70204945(+) A-I intron -    22327324
chr12:70204946(+) A-I intron -    22327324
chr12:70204956(+) A-I intron -    22327324
chr12:70204971(+) A-I intron -    21960545
chr12:70204898(+) A-G intron -    22484847
chr12:70204904(+) A-G intron -    22484847
chr12:70204956(+) A-G intron -    22484847
chr12:70211838(+) A-C intron -    22484847
chr12:70211840(+) A-C intron -    22484847
chr12:70211843(+) C-T intron -    22484847
chr12:70212129(+) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RAB3IP
chr12:70133461-70133462(+) m6A 5'UTR//intron       -
chr12:70133487-70133488(+) m6A 5'UTR//intron       -
chr12:70149225-70149226(+) m6A 3'UTR//CDS       -
chr12:70149249-70149250(+) m6A 3'UTR//CDS       -
chr12:70149275-70149276(+) m6A CDS//intron       -
chr12:70149287-70149288(+) m6A CDS//intron       -
chr12:70149373-70149374(+) m6A 3'UTR//CDS       -
chr12:70150261-70150262(+) m6A 3'UTR//CDS       22608085
chr12:70150424-70150425(+) m6A 3'UTR//CDS       27773535//22608085
chr12:70178558-70178559(+) m6A 3'UTR//5'UTR//CDS       24981863
chr12:70178573-70178574(+) m6A 3'UTR//5'UTR//CDS       24981863
chr12:70188269-70188270(+) m6A 3'UTR//CDS       24981863
chr12:70188956-70188957(+) m6A 3'UTR//CDS       24981863
chr12:70189016-70189017(+) m6A CDS       27773535
chr12:70209325-70209326(+) m6A 3'UTR//exon       24981863//22608085
chr12:70209377-70209378(+) m6A 3'UTR//exon       24981863//27773535//22608085
chr12:70209413-70209414(+) m6A 3'UTR//exon       27773535
chr12:70209477-70209478(+) m6A 3'UTR//exon       27773535
chr12:70210665-70210666(+) m6A 3'UTR//exon       25456834//24981863//22608085
chr12:70210673-70210674(+) m6A 3'UTR//exon       25456834//24981863//22608085
chr12:70210697-70210698(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr12:70210736-70210737(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr12:70210747-70210748(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr12:70210754-70210755(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22608085
chr12:70210847-70210848(+) m6A 3'UTR//exon       27773535
chr12:70210889-70210890(+) m6A 3'UTR//exon       27773535
chr12:70211424-70211425(+) m6A 3'UTR       24981863
chr12:70211478-70211479(+) m6A 3'UTR       24981863
chr12:70211930-70211931(+) m6A 3'UTR       -
chr12:70213304-70213305(+) m6A 3'UTR       25456834//24981863//22608085
chr12:70213416-70213417(+) m6A 3'UTR       24209618//25456834//24981863//22608085
chr12:70213497-70213498(+) m6A 3'UTR       25456834//24981863//22608085
chr12:70213505-70213506(+) m6A 3'UTR       25456834//24981863//22608085
chr12:70213558-70213559(+) m6A 3'UTR       25456834//24981863//22608085
chr12:70213584-70213585(+) m6A 3'UTR       25456834//24981863//22608085
chr12:70213617-70213618(+) m6A 3'UTR       22608085
chr12:70213676-70213677(+) m6A 3'UTR       22608085
chr12:70213715-70213716(+) m6A 3'UTR       24981863//22608085
chr12:70213733-70213734(+) m6A 3'UTR       24981863//22608085
chr12:70214111-70214112(+) m6A 3'UTR       24981863
chr12:70214186-70214187(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-320d
Exosome Pooled sera     27278097
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Plasma     23663360
Exosome Breast cancer cell lines (MCF-7|MDA-MB-231)     24468161
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
RAB3IP
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Membrane HCC cell line (HepG2)     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-320d
Eloxatine 5310940 Drug interaction    RC00007888
5-Fluorouracil 3385 Drug interaction    RC00007885
Doxorubicin 31703 Drug interaction    RC00007886
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007884
Docetaxel 148124 Drug interaction    RC00007887
Marine fungal metabolite 1386A - Drug interaction    RC00007889
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-320d
Topotecan       60700
Pha-665752       10461815

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-320d
Interactor2: RAB3IP

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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