Basic Information:

  VIRBase ID:  

HHID00071145

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320d:  MIMAT0006764          ACBD3:  NM_022735     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-320d	ACBD3
miRBase Accession/Entrez ID	MIMAT0006764	64746
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	GCP60//GOCAP1//GOLPH1//PAP7

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-320d	rs1013069487 chr13:40727828    T/C rs1212045422 chr13:40727836    ACC/A rs1287962814 chr13:40727836    A/G rs755131134 chr13:40727846    T/C rs757049836 chr13:40727829    C/A rs757049836 chr13:40727829    C/T rs772990558 chr13:40727831    T/C rs1441164440 chrX:140926173    C/G rs1556096982 chrX:140926178    C/G rs782742486 chrX:140926174    C/G rs782742486 chrX:140926174    C/T rs1371780032 chr13:40727825    TCATCCTCTCAACCCAGC/T rs535778068 chr13:40727842    C/G rs569951817 chr13:40727839    C/T rs1330731340 chrX:140926183    C/G rs1384057774 chrX:140926185    G/A rs1422735584 chrX:140926184    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ACBD3	chr1:226361667(-) A-I      intronic chr1:226361643(-) A-I      intronic chr1:226361640(-) A-I      intronic chr1:226350595(-) A-I      intronic chr1:226359744(-) A-I      intronic chr1:226359780(-) A-I      intronic chr1:226361642(-) A-I      intronic chr1:226361631(-) A-I      intronic chr1:226361632(-) A-I      intronic chr1:226361636(-) A-I      intronic chr1:226359774(-) A-I      intronic chr1:226361637(-) A-I      intronic chr1:226359748(-) A-I      intronic chr1:226356692(-) A-I      intronic chr1:226351656(-) A-I      intronic chr1:226371886(-) A-I      intronic chr1:226371770(-) A-I      intronic chr1:226356720(-) A-I      intronic chr1:226357678(-) A-I      intronic chr1:226359669(-) A-I      intronic chr1:226358538(-) A-I      intronic chr1:226358557(-) A-I      intronic chr1:226371703(-) A-I      intronic chr1:226371696(-) A-I      intronic chr1:226358573(-) A-I      intronic chr1:226339544(-) A-I      intronic chr1:226339664(-) A-I      intronic chr1:226371658(-) A-I      intronic chr1:226371528(-) A-I      intronic chr1:226371523(-) A-I      intronic chr1:226368648(-) A-I      intronic chr1:226371463(-) A-I      intronic chr1:226371112(-) A-I      intronic chr1:226337339(-) A-I      intronic chr1:226371089(-) A-I      intronic chr1:226368661(-) A-I      intronic chr1:226368614(-) A-I      intronic chr1:226358586(-) A-I      intronic chr1:226367512(-) A-I      intronic chr1:226358629(-) A-I      intronic chr1:226339686(-) A-I      intronic chr1:226367507(-) A-I      intronic chr1:226358692(-) A-I      intronic chr1:226366229(-) A-I      intronic chr1:226366194(-) A-I      intronic chr1:226366189(-) A-I      intronic chr1:226366176(-) A-I      intronic chr1:226366154(-) A-I      intronic chr1:226366152(-) A-I      intronic chr1:226366107(-) A-I      intronic chr1:226366078(-) A-I      intronic chr1:226358754(-) A-I      intronic chr1:226339706(-) A-I      intronic chr1:226360958(-) A-I      intronic chr1:226360750(-) A-I      intronic chr1:226360746(-) A-I      intronic chr1:226360723(-) A-I      intronic chr1:226360722(-) A-I      intronic chr1:226360710(-) A-I      intronic chr1:226358986(-) A-I      intronic chr1:226359139(-) A-I      intronic chr1:226360605(-) A-I      intronic chr1:226360521(-) A-I      intronic chr1:226360490(-) A-I      intronic chr1:226360402(-) A-I      intronic chr1:226360401(-) A-I      intronic chr1:226360389(-) A-I      intronic chr1:226351630(-) A-I      intronic chr1:226359640(-) A-I      intronic chr1:226371718(-) A-I      intronic chr1:226359516(-) A-I      intronic chr1:226359486(-) A-I      intronic chr1:226359427(-) A-I      intronic chr1:226359414(-) A-I      intronic chr1:226359141(-) A-I      intronic chr1:226337327(-) A-I      intronic chr1:226337334(-) A-I      intronic chr1:226337349(-) A-I      intronic chr1:226359377(-) A-I      intronic chr1:226359363(-) A-I      intronic chr1:226337422(-) A-I      intronic chr1:226359269(-) A-I      intronic chr1:226359145(-) A-I      intronic chr1:226351642(-) A-I      intronic chr1:226360505(-) A-I      intronic chr1:226371502(-) A-I      intronic chr1:226358147(-) A-I      intronic chr1:226360163(-) A-I      intronic chr1:226356570(-) A-I      intronic chr1:226334864(-) A-I      intronic chr1:226365037(-) A-I      intronic chr1:226354234(-) A-I      intronic chr1:226359708(-) A-I      intronic chr1:226334825(-) A-I      intronic chr1:226359416(-) A-I      intronic chr1:226357479(-) A-I      intronic chr1:226361615(-) A-I      intronic chr1:226357540(-) A-I      intronic chr1:226371450(-) A-I      intronic chr1:226359336(-) A-I      intronic chr1:226359026(-) A-I      intronic chr1:226351741(-) A-I      intronic chr1:226357575(-) A-I      intronic chr1:226357659(-) A-I      intronic chr1:226359412(-) A-I      intronic chr1:226368449(-) A-I      intronic chr1:226357684(-) A-I      intronic chr1:226365529(-) A-I      intronic chr1:226359046(-) A-I      intronic chr1:226358645(-) A-I      intronic chr1:226358635(-) A-I      intronic chr1:226360164(-) A-I      intronic chr1:226371461(-) A-I      intronic chr1:226359009(-) A-I      intronic chr1:226361624(-) A-I      intronic chr1:226371835(-) A-I      intronic chr1:226370967(-) A-I      intronic chr1:226359612(-) A-I      intronic chr1:226365694(-) A-I      intronic chr1:226372567(-) A-I      intronic chr1:226334623(-) A-I      intronic chr1:226359481(-) A-I      intronic chr1:226371533(-) A-I      intronic chr1:226354084(-) A-I      intronic chr1:226371473(-) A-I      intronic chr1:226357348(-) A-I      intronic chr1:226358080(-) A-I      intronic chr1:226359321(-) A-I      intronic chr1:226334655(-) A-I      intronic chr1:226334841(-) A-I      intronic chr1:226358717(-) A-I      intronic chr1:226371025(-) A-I      intronic chr1:226351817(-) A-I      intronic chr1:226365512(-) A-I      intronic chr1:226353985(-) A-I      intronic chr1:226359406(-) A-I      intronic chr1:226368618(-) A-I      intronic chr1:226358650(-) A-I      intronic chr1:226371015(-) A-I      intronic chr1:226371155(-) A-I      intronic chr1:226360922(-) A-I      intronic chr1:226360749(-) A-I      intronic chr1:226367528(-) A-I      intronic chr1:226363970(-) A-I      intronic chr1:226334817(-) A-I      intronic chr1:226334721(-) A-I      intronic chr1:226350622(-) A-I      intronic chr1:226357991(-) A-I      intronic chr1:226370907(-) A-I      intronic chr1:226365544(-) A-I      intronic chr1:226371169(-) A-I      intronic chr1:226364902(-) A-I      intronic chr1:226350613(-) A-I      intronic chr1:226361559(-) A-I      intronic chr1:226363872(-) A-I      intronic chr1:226359747(-) A-I      intronic chr1:226359699(-) A-I      intronic chr1:226354059(-) A-I      intronic chr1:226358148(-) A-I      intronic chr1:226358605(-) A-I      intronic chr1:226357643(-) A-I      intronic chr1:226371423(-) A-I      intronic chr1:226356743(-) A-I      intronic chr1:226371880(-) A-I      intronic chr1:226365027(-) A-I      intronic chr1:226360764(-) A-I      intronic chr1:226356655(-) A-I      intronic chr1:226371498(-) A-I      intronic chr1:226357583(-) A-I      intronic chr1:226356702(-) A-I      intronic chr1:226365568(-) A-I      intronic chr1:226368617(-) A-I      intronic chr1:226359324(-) A-I      intronic chr1:226357077(-) A-I      intronic chr1:226371888(-) A-I      intronic chr1:226350728(-) A-I      intronic chr1:226366027(-) A-I      intronic chr1:226359707(-) A-I      intronic chr1:226350614(-) A-I      intronic chr1:226359122(-) A-I      intronic chr1:226334714(-) A-I      intronic chr1:226360732(-) A-I      intronic chr1:226354060(-) A-I      intronic chr1:226371420(-) A-I      intronic chr1:226357566(-) A-I      intronic chr1:226350715(-) A-I      intronic chr1:226357384(-) A-I      intronic chr1:226350666(-) A-I      intronic chr1:226359344(-) A-I      intronic chr1:226364959(-) A-I      intronic chr1:226354325(-) A-I      intronic chr1:226371847(-) A-I      intronic chr1:226339632(-) A-I      intronic chr1:226351745(-) A-I      intronic chr1:226358609(-) A-I      intronic chr1:226360939(-) A-I      intronic chr1:226364897(-) A-I      intronic chr1:226359600(-) A-I      intronic chr1:226371041(-) A-I      intronic chr1:226360787(-) A-I      intronic chr1:226362404(-) A-I      intronic chr1:226365608(-) A-I      intronic chr1:226360188(-) A-I      intronic chr1:226358659(-) A-I      intronic chr1:226357560(-) A-I      intronic chr1:226361692(-) A-I      intronic chr1:226353994(-) A-I      intronic chr1:226359407(-) A-I      intronic chr1:226360189(-) A-I      intronic chr1:226354412(-) A-I      intronic chr1:226371829(-) A-I      intronic chr1:226358070(-) A-I      intronic chr1:226365588(-) A-I      intronic chr1:226359494(-) A-I      intronic chr1:226365169(-) A-I      intronic chr1:226371063(-) A-I      intronic chr1:226358662(-) A-I      intronic chr1:226358711(-) A-I      intronic chr1:226365582(-) A-I      intronic chr1:226360861(-) A-I      intronic chr1:226357626(-) A-I      intronic chr1:226334704(-) A-I      intronic chr1:226365604(-) A-I      intronic chr1:226371468(-) A-I      intronic chr1:226353940(-) A-I      intronic chr1:226361641(-) A-I      intronic chr1:226353954(-) A-I      intronic chr1:226361702(-) A-I      intronic chr1:226334713(-) A-I      intronic chr1:226350755(-) A-I      intronic chr1:226334837(-) A-I      intronic chr1:226368455(-) A-I      intronic chr1:226359403(-) A-I      intronic chr1:226365637(-) A-I      intronic chr1:226357614(-) A-I      intronic chr1:226359277(-) A-I      intronic chr1:226371554(-) A-I      intronic chr1:226357604(-) A-I      intronic chr1:226357466(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ACBD3	chr1:226334655(-) A-I intron -    15342557 chr1:226334668(-) A-I intron -    15342557 chr1:226334704(-) A-I intron -    15342557 chr1:226334713(-) A-I intron -    15342557 chr1:226334714(-) A-I intron -    15342557 chr1:226334721(-) A-I intron -    15342557 chr1:226334825(-) A-I intron -    15342557 chr1:226334837(-) A-I intron -    15342557 chr1:226334841(-) A-I intron -    15342557 chr1:226357604(-) A-I intron -    22327324 chr1:226356731(-) A-I intron -    21960545 chr1:226358605(-) A-I intron -    21960545 chr1:226358717(-) A-I intron -    21960545 chr1:226359145(-) A-I intron -    21960545 chr1:226360163(-) A-I intron -    21960545 chr1:226360189(-) A-I intron -    21960545 chr1:226360210(-) A-I intron -    21960545 chr1:226360861(-) A-I intron -    21960545 chr1:226354054(-) C-T intron -    22484847 chr1:226354059(-) A-G intron -    22484847 chr1:226354060(-) A-G intron -    22484847 chr1:226354084(-) A-G intron -    22484847 chr1:226357604(-) A-G intron -    22484847 chr1:226357614(-) A-G intron -    22484847 chr1:226358605(-) A-G intron -    22484847 chr1:226358659(-) A-G intron -    22484847 chr1:226358717(-) A-G intron -    22484847 chr1:226359122(-) A-G intron -    22484847 chr1:226359277(-) A-G intron -    22484847 chr1:226359321(-) A-G intron -    22484847 chr1:226359324(-) A-G intron -    22484847 chr1:226359336(-) A-G intron -    22484847 chr1:226359344(-) A-G intron -    22484847 chr1:226359407(-) A-G intron -    22484847 chr1:226359412(-) A-G intron -    22484847 chr1:226359481(-) A-G intron -    22484847 chr1:226359494(-) A-G intron -    22484847 chr1:226359612(-) A-G intron -    22484847 chr1:226359747(-) A-G intron -    22484847 chr1:226360163(-) A-G intron -    22484847 chr1:226360764(-) A-G intron -    22484847 chr1:226361708(-) C-G intron -    22484847 chr1:226365037(-) A-G intron -    22484847 chr1:226365512(-) A-G intron -    22484847 chr1:226365544(-) A-G intron -    22484847 chr1:226365568(-) A-G intron -    22484847 chr1:226365604(-) A-G intron -    22484847 chr1:226365608(-) A-G intron -    22484847 chr1:226365694(-) A-G intron -    22484847 chr1:226368449(-) A-G intron -    22484847 chr1:226368455(-) A-G intron -    22484847 chr1:226368617(-) A-G intron -    22484847 chr1:226368618(-) A-G intron -    22484847 chr1:226370907(-) A-G intron -    22484847 chr1:226370967(-) A-G intron -    22484847 chr1:226371015(-) A-G intron -    22484847 chr1:226371025(-) A-G intron -    22484847 chr1:226371155(-) A-G intron -    22484847 chr1:226371169(-) A-G intron -    22484847 chr1:226371423(-) A-G intron -    22484847 chr1:226371461(-) A-G intron -    22484847 chr1:226371468(-) A-G intron -    22484847 chr1:226371498(-) A-G intron -    22484847 chr1:226371502(-) A-G intron -    22484847 chr1:226371533(-) A-G intron -    22484847 chr1:226371554(-) A-G intron -    22484847 chr1:226371835(-) A-G intron -    22484847 chr1:226371880(-) A-G intron -    22484847 chr1:226371888(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ACBD3	chr1:226333370-226333371(-) m6A 3'UTR       26404942 chr1:226334012-226334013(-) m6A 3'UTR       27773535 chr1:226334107-226334108(-) m6A 3'UTR       24981863//27773535//22575960//22608085 chr1:226334150-226334151(-) m6A 3'UTR       24209618//25456834//24981863//27773535//22575960//22608085 chr1:226334180-226334181(-) m6A 3'UTR       24209618//25456834//24981863//27773535//22575960//22608085 chr1:226334440-226334441(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:226334518-226334519(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:226340037-226340038(-) m1A CDS       26863196 chr1:226340091-226340092(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:226340104-226340105(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:226340142-226340143(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:226340265-226340266(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr1:226340284-226340285(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22608085 chr1:226342354-226342355(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22608085 chr1:226342387-226342388(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085 chr1:226342393-226342394(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085 chr1:226342419-226342420(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085 chr1:226342429-226342430(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085 chr1:226342519-226342520(-) m6A CDS//exon       27773535 chr1:226346974-226346975(-) m6A CDS//intron       27773535 chr1:226346981-226346982(-) m6A CDS//intron       24209618//24981863//27773535 chr1:226347027-226347028(-) m6A CDS//intron       24209618//24981863//27773535//27371828 chr1:226347035-226347036(-) m6A CDS//intron       24209618//24981863//27773535//27371828 chr1:226349258-226349259(-) m1A CDS//exon       26863196 chr1:226349306-226349307(-) m1A CDS//exon       26863196 chr1:226349334-226349335(-) Am CDS       - chr1:226352516-226352517(-) Tm CDS       - chr1:226352606-226352607(-) m6A CDS       24209618//27773535 chr1:226353607-226353608(-) m6A CDS       24209618//27773535 chr1:226374311-226374312(-) m6A CDS       24209618//24981863//27371828//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-320d	Exosome Pooled sera     27278097 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Plasma     23663360 Exosome Breast cancer cell lines (MCF-7|MDA-MB-231)     24468161 Exosome Colon cancer cell line (LIM1863)     25330373 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells     - Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	ACBD3	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-320d	Eloxatine 5310940 Drug interaction    RC00007888 5-Fluorouracil 3385 Drug interaction    RC00007885 Doxorubicin 31703 Drug interaction    RC00007886 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007884 Docetaxel 148124 Drug interaction    RC00007887 Marine fungal metabolite 1386A - Drug interaction    RC00007889

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-320d	Topotecan       60700 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-320d
Interactor2: ACBD3

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.