Detail Information

Basic Information:


  VIRBase ID:  

HHID00071126

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320d:           RAB11FIP2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-320d RAB11FIP2
miRBase
Accession/Entrez ID		 MIMAT0006764 22841
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - nRip11//Rab11-FIP2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-320d
rs1013069487 chr13:40727828    T/C
rs1212045422 chr13:40727836    ACC/A
rs1287962814 chr13:40727836    A/G
rs755131134 chr13:40727846    T/C
rs757049836 chr13:40727829    C/A
rs757049836 chr13:40727829    C/T
rs772990558 chr13:40727831    T/C
rs1441164440 chrX:140926173    C/G
rs1556096982 chrX:140926178    C/G
rs782742486 chrX:140926174    C/G
rs782742486 chrX:140926174    C/T
rs1371780032 chr13:40727825    TCATCCTCTCAACCCAGC/T
rs535778068 chr13:40727842    C/G
rs569951817 chr13:40727839    C/T
rs1330731340 chrX:140926183    C/G
rs1384057774 chrX:140926185    G/A
rs1422735584 chrX:140926184    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RAB11FIP2
chr10:119776622(-) A-I      intronic
chr10:119776638(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RAB11FIP2
chr10:119765259-119765260(-) m6A 3'UTR       24981863
chr10:119765266-119765267(-) m6A 3'UTR//exon       24981863
chr10:119765376-119765377(-) m6A 3'UTR//intron       24981863//27773535
chr10:119765396-119765397(-) m6A 3'UTR//intron       27773535
chr10:119765407-119765408(-) m6A 3'UTR//intron       27773535
chr10:119767400-119767401(-) m6A 3'UTR//intron       24981863
chr10:119767411-119767412(-) m6A 3'UTR//intron       24981863
chr10:119768259-119768260(-) m6A 3'UTR//intron       27773535
chr10:119768351-119768352(-) m6A 3'UTR//intron       24981863//27773535//22608085
chr10:119768424-119768425(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr10:119768441-119768442(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085
chr10:119768477-119768478(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//27371828//22608085
chr10:119768544-119768545(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768611-119768612(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768619-119768620(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768635-119768636(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768652-119768653(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768661-119768662(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119774591-119774592(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119798554-119798555(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr10:119798625-119798626(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr10:119798724-119798725(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119798749-119798750(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119798756-119798757(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119798850-119798851(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr10:119798896-119798897(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr10:119798924-119798925(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr10:119799648-119799649(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799670-119799671(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799684-119799685(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799709-119799710(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799799-119799800(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799894-119799895(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr10:119799951-119799952(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr10:119799956-119799957(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr10:119799995-119799996(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr10:119800034-119800035(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr10:119800054-119800055(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr10:119805325-119805326(-) m6A CDS       24284625//24981863//27773535//22608085
chr10:119805342-119805343(-) m6A CDS       24981863//27773535//22608085
chr10:119805866-119805867(-) m6A 5'UTR       24284625
chr10:119805947-119805948(-) m6A 5'UTR       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-320d
Exosome Pooled sera     27278097
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Plasma     23663360
Exosome Breast cancer cell lines (MCF-7|MDA-MB-231)     24468161
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
RAB11FIP2
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-320d
Eloxatine 5310940 Drug interaction    RC00007888
5-Fluorouracil 3385 Drug interaction    RC00007885
Doxorubicin 31703 Drug interaction    RC00007886
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007884
Docetaxel 148124 Drug interaction    RC00007887
Marine fungal metabolite 1386A - Drug interaction    RC00007889
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-320d
Topotecan       60700
Pha-665752       10461815

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-320d
Interactor2: RAB11FIP2

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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