Detail Information

Basic Information:


  VIRBase ID:  

HHID00071023

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1255b-5p:           DHX36:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1255b-5p DHX36
miRBase
Accession/Entrez ID		 MIMAT0005945 170506
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DDX36//G4R1//MLEL1//RHAU

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1255b-5p
rs1159375777 chr4:36426410    C/T
rs1214571859 chr4:36426418    G/A
rs1239891775 chr4:36426417    T/G
rs6841938 chr4:36426426    G/A
rs934445568 chr4:36426407    C/T
rs1163338680 chr1:167998678    A/T
rs755372990 chr1:167998677    GA/G
rs931584044 chr1:167998685    T/A
rs963713310 chr1:167998665    C/T
rs1053333800 chr4:36426425    C/T
rs139535532 chr4:36426424    C/A
rs189709980 chr1:167998666    G/A
rs189709980 chr1:167998666    G/C
rs975287373 chr1:167998672    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR DHX36
chr3:154013760(-) A-I      intronic
chr3:154013730(-) A-I      intronic
chr3:154013776(-) A-I      intronic
chr3:154014019(-) A-I      intronic
chr3:154014021(-) A-I      intronic
chr3:154014082(-) A-I      intronic
chr3:154014163(-) A-I      intronic
chr3:154014176(-) A-I      intronic
chr3:154004725(-) A-I      intronic
chr3:154014187(-) A-I      intronic
chr3:153993280(-) A-I      3'UTR
chr3:154004729(-) A-I      intronic
chr3:154013654(-) A-I      intronic
chr3:154013751(-) A-I      intronic
chr3:154013824(-) A-I      intronic
chr3:154016950(-) A-I      intronic
chr3:154016881(-) A-I      intronic
chr3:154013821(-) A-I      intronic
chr3:154002243(-) A-I      intronic
chr3:153991878(-) A-I      3'UTR
chr3:153992014(-) A-I      3'UTR
chr3:154015391(-) A-I      intronic
chr3:153996390(-) A-I      intronic
chr3:154013752(-) A-I      intronic
chr3:154016523(-) A-I      intronic
chr3:154013649(-) A-I      intronic
chr3:154013642(-) A-I      intronic
chr3:154013685(-) A-I      intronic
chr3:154017065(-) A-I      intronic
chr3:154013619(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED DHX36
chr3:154013619(-) A-G intron -    22484847
chr3:154013642(-) A-G intron -    22484847
chr3:154013649(-) A-G intron -    22484847
chr3:154013745(-) A-G intron -    22484847
chr3:154013752(-) A-G intron -    22484847
chr3:154013753(-) A-G intron -    22484847
chr3:154014074(-) A-G intron -    22484847
chr3:154016523(-) A-G intron -    22484847
chr3:154016881(-) A-G intron -    22484847
chr3:154016890(-) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DHX36
chr3:153992184-153992185(-) m6A 3'UTR       22608085
chr3:153992205-153992206(-) m6A 3'UTR       22608085
chr3:153992275-153992276(-) m6A 3'UTR       24981863//22608085
chr3:153992303-153992304(-) m6A 3'UTR       24981863//22608085
chr3:153992309-153992310(-) m6A 3'UTR       24981863//22608085
chr3:153992315-153992316(-) m6A 3'UTR       24981863//22608085
chr3:153992346-153992347(-) m6A 3'UTR       22608085
chr3:153993528-153993529(-) m6A 3'UTR       27773535
chr3:153993553-153993554(-) m6A 3'UTR       27773535
chr3:153993576-153993577(-) m6A 3'UTR       27773535
chr3:153993823-153993824(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22608085
chr3:153993867-153993868(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr3:153993873-153993874(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:153993881-153993882(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:153993996-153993997(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:153994021-153994022(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:153994032-153994033(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:153994059-153994060(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:153994083-153994084(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:153994130-153994131(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:153994363-153994364(-) m6A exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:154018786-154018787(-) m6A CDS       24981863//27773535
chr3:154018846-154018847(-) m6A CDS       24981863//27773535
chr3:154018894-154018895(-) m6A CDS       24981863//27773535
chr3:154018903-154018904(-) m6A CDS       24981863//27773535
chr3:154027527-154027528(-) Y CDS       26075521
chr3:154029480-154029481(-) m6A exon//intron       27773535
chr3:154032895-154032896(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085
chr3:154032902-154032903(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085
chr3:154032912-154032913(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085
chr3:154032961-154032962(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22608085
chr3:154033024-154033025(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr3:154033042-154033043(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr3:154033889-154033890(-) Y CDS//exon       25219674
chr3:154033916-154033917(-) m6A CDS//exon       24209618//24981863//27773535//27371828
chr3:154036929-154036930(-) m1A 5'UTR//intron       26863196
chr3:154036937-154036938(-) m6A 5'UTR//intron       24209618//24981863//27773535//27371828
chr3:154041984-154041985(-) m6A CDS//exon       24209618//24981863//27773535//27371828//27773536//22575960
chr3:154041998-154041999(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960
chr3:154042182-154042183(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr3:154042207-154042208(-) m6A 5'UTR       24284625//25456834//24981863//27773535//27371828//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1255b-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
DHX36
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1255b-5p
Interactor2: DHX36

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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