Detail Information

Basic Information:


  VIRBase ID:  

HHID00070994

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1255b-5p:           PABPC4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1255b-5p PABPC4
miRBase
Accession/Entrez ID		 MIMAT0005945 8761
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - APP-1//APP1//iPABP//PABP4

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1255b-5p
rs1159375777 chr4:36426410    C/T
rs1214571859 chr4:36426418    G/A
rs1239891775 chr4:36426417    T/G
rs6841938 chr4:36426426    G/A
rs934445568 chr4:36426407    C/T
rs1163338680 chr1:167998678    A/T
rs755372990 chr1:167998677    GA/G
rs931584044 chr1:167998685    T/A
rs963713310 chr1:167998665    C/T
rs1053333800 chr4:36426425    C/T
rs139535532 chr4:36426424    C/A
rs189709980 chr1:167998666    G/A
rs189709980 chr1:167998666    G/C
rs975287373 chr1:167998672    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PABPC4
chr1:40026990(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PABPC4
chr1:40026888-40026889(-) m6A exon//intron       27773535
chr1:40029270-40029271(-) m6A exon//intron       22575960
chr1:40030820-40030821(-) Y 3'UTR//CDS//exon       25219674//26075521
chr1:40033495-40033496(-) m6A 3'UTR//CDS//exon       24981863//28052920//27773535
chr1:40033580-40033581(-) m6A exon//intron       24981863//28052920//27773535
chr1:40034497-40034498(-) m6A 3'UTR//CDS//exon       24981863//28052920//27773535//22575960//22608085
chr1:40034506-40034507(-) m6A 3'UTR//CDS//exon       24981863//28052920//27773535//22575960//22608085
chr1:40035284-40035285(-) m6A 3'UTR//CDS//exon//intron       24981863//27773535
chr1:40035355-40035356(-) m6A 3'UTR//CDS//exon//intron       24981863
chr1:40038122-40038123(-) Tm CDS       -
chr1:40038131-40038132(-) m6A CDS       27773535
chr1:40038137-40038138(-) m6A CDS       27773535
chr1:40038233-40038234(-) m6A CDS       27773535//22575960
chr1:40038242-40038243(-) m6A CDS       27773535//22575960
chr1:40041882-40041883(-) m6A 5'UTR       24284625//26404942//22575960
chr1:40042046-40042047(-) m6A 5'UTR//intron       24209618
chr1:40042317-40042318(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1255b-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
PABPC4
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1255b-5p
Interactor2: PABPC4

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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