Detail Information

Basic Information:


  VIRBase ID:  

HHID00070900

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1277-3p:           EXOC8:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1277-3p EXOC8
miRBase
Accession/Entrez ID		 MIMAT0005933 149371
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - EXO84//Exo84p//NEDMISB//SEC84

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1277-3p
rs1314558247 chrX:118386454    T/C
rs1401463031 chrX:118386451    A/G
rs1415304019 chrX:118386453    A/G
rs747921534 chrX:118386449    A/G
rs759040197 chrX:118386457    AT/A
rs777048487 chrX:118386450    T/C
rs1160189721 chrX:118386443    G/A
rs1184902110 chrX:118386443    GTAGA/G
rs1298186191 chrX:118386446    G/GAT
rs770130422 chrX:118386442    C/T
rs778901514 chrX:118386447    A/C
rs778901514 chrX:118386447    A/G
rs778901514 chrX:118386447    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR EXOC8
chr1:231470972(-) A-I      3'UTR
chr1:231470953(-) A-I      3'UTR
chr1:231470940(-) A-I      3'UTR
chr1:231470904(-) A-I      3'UTR
chr1:231470789(-) A-I      3'UTR
chr1:231470820(-) A-I      3'UTR
chr1:231470858(-) A-I      3'UTR
chr1:231470886(-) A-I      3'UTR
chr1:231470891(-) A-I      3'UTR
chr1:231470846(-) A-I      3'UTR
chr1:231470864(-) A-I      3'UTR
chr1:231470929(-) A-I      3'UTR
chr1:231470874(-) A-I      3'UTR
chr1:231470871(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED EXOC8
chr1:231470998(-) C-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase EXOC8
chr1:231468613-231468614(-) m6A 3'UTR       27773535
chr1:231470533-231470534(-) m6A 3'UTR       22608085
chr1:231470608-231470609(-) m6A 3'UTR       24981863//22608085
chr1:231470644-231470645(-) m6A 3'UTR       24981863//22608085
chr1:231470866-231470867(-) m6A 3'UTR       27773535
chr1:231470981-231470982(-) m6A 3'UTR       24284625//27773535
chr1:231471216-231471217(-) m6A 3'UTR       27773535
chr1:231471355-231471356(-) m6A CDS       24284625//24981863//26404942//27773535//27371828//22575960//22608085
chr1:231471394-231471395(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr1:231471441-231471442(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr1:231471466-231471467(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr1:231471625-231471626(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr1:231471656-231471657(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr1:231471755-231471756(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr1:231471790-231471791(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr1:231471842-231471843(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr1:231471883-231471884(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr1:231472083-231472084(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085
chr1:231472190-231472191(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085
chr1:231472300-231472301(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr1:231472357-231472358(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr1:231472381-231472382(-) m6A CDS       24284625//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr1:231472400-231472401(-) m6A CDS       24284625//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr1:231472436-231472437(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr1:231472463-231472464(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr1:231472499-231472500(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr1:231472534-231472535(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr1:231472541-231472542(-) m1A CDS       26863410
chr1:231472655-231472656(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr1:231472745-231472746(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr1:231472763-231472764(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr1:231472907-231472908(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr1:231472928-231472929(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr1:231472951-231472952(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr1:231473099-231473100(-) m6A CDS       24284625//27371828//27773536//22608085
chr1:231473294-231473295(-) m6A CDS       24284625//24981863//27371828//27773536//22608085
chr1:231473318-231473319(-) m6A CDS       24284625//25456834//24981863//27371828//27773536//22608085
chr1:231473372-231473373(-) m6A CDS       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr1:231473378-231473379(-) m6A CDS       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr1:231473471-231473472(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr1:231473502-231473503(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr1:231473548-231473549(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1277-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
EXOC8
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1277-3p
Interactor2: EXOC8

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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