Basic Information:

  VIRBase ID:  

HHID00070858

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1277-3p:  MIMAT0005933          GSKIP:  NM_001271905     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1277-3p	GSKIP
miRBase Accession/Entrez ID	MIMAT0005933	51527
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C14orf129//HSPC210

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1277-3p	rs1314558247 chrX:118386454    T/C rs1401463031 chrX:118386451    A/G rs1415304019 chrX:118386453    A/G rs747921534 chrX:118386449    A/G rs759040197 chrX:118386457    AT/A rs777048487 chrX:118386450    T/C rs1160189721 chrX:118386443    G/A rs1184902110 chrX:118386443    GTAGA/G rs1298186191 chrX:118386446    G/GAT rs770130422 chrX:118386442    C/T rs778901514 chrX:118386447    A/C rs778901514 chrX:118386447    A/G rs778901514 chrX:118386447    A/T

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GSKIP	chr14:96829823-96829824(+) m1A 5'UTR       26863410 chr14:96829884-96829885(+) m1A 5'UTR//exon       26863196//26863410 chr14:96830369-96830370(+) m6A 5'UTR//intron       25456834 chr14:96830443-96830444(+) m6A 5'UTR//intron       24209618 chr14:96830456-96830457(+) m6A 5'UTR//intron       24209618 chr14:96830759-96830760(+) m6A 5'UTR//intron       24209618//25456834//24981863//22608085 chr14:96830765-96830766(+) m6A 5'UTR//intron       24209618//25456834//24981863//22608085 chr14:96830778-96830779(+) m6A 5'UTR//intron       24209618//25456834//24981863//22608085 chr14:96830899-96830900(+) m6A 5'UTR//intron       24284625//22608085 chr14:96830940-96830941(+) m6A 5'UTR//intron       - chr14:96830996-96830997(+) m6A 5'UTR//intron       24981863 chr14:96831097-96831098(+) m6A 5'UTR//intron       25456834//24981863//22608085 chr14:96831119-96831120(+) m6A 5'UTR//intron       25456834//24981863//22608085 chr14:96831204-96831205(+) m6A 5'UTR//intron       24284625//25456834//24981863//22608085 chr14:96831311-96831312(+) m6A 5'UTR//intron       22608085 chr14:96831324-96831325(+) m6A 5'UTR//intron       22608085 chr14:96845319-96845320(+) m6A 5'UTR//intron       24981863 chr14:96845346-96845347(+) m6A 5'UTR//intron       24981863 chr14:96848590-96848591(+) m6A CDS       25456834//24981863//22608085 chr14:96848665-96848666(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr14:96848678-96848679(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr14:96848791-96848792(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr14:96848804-96848805(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr14:96848820-96848821(+) m6A CDS       24284625//24209618//24981863//22608085 chr14:96851050-96851051(+) Y intron       25219674 chr14:96851901-96851902(+) m6A CDS       24284625//24209618//24981863//22608085 chr14:96851916-96851917(+) m6A CDS       24284625//24209618//24981863//22608085 chr14:96851987-96851988(+) m6A CDS       24284625//25456834//24981863//26404942//22608085 chr14:96852011-96852012(+) m6A CDS       24284625//25456834//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1277-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	GSKIP	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1277-3p
Interactor2: GSKIP

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.