Detail Information

Basic Information:


  VIRBase ID:  

HHID00070801

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:           PLD6:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1276 PLD6
miRBase
Accession/Entrez ID		 MIMAT0005930 201164
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ZUC

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1276
rs372186220 chr15:85770551    C/T
rs759704230 chr15:85770557    A/G
rs949716743 chr15:85770550    T/C
rs1469123493 chr15:85770565    T/C
rs34381260 chr15:85770563    CT/C
rs34381260 chr15:85770563    CT/CTT
rs750237476 chr15:85770564    T/C
rs764239400 chr15:85770562    T/C
rs769744052 chr15:85770560    G/A
rs775843960 chr15:85770561    C/A
rs775843960 chr15:85770561    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PLD6
chr17:17105038(-) A-I      3'UTR
chr17:17105050(-) A-I      3'UTR
chr17:17105090(-) A-I      3'UTR
chr17:17105022(-) A-I      3'UTR
chr17:17105200(-) A-I      3'UTR
chr17:17105091(-) A-I      3'UTR
chr17:17105216(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PLD6
chr17:17105811-17105812(-) m6A 3'UTR       24284625//27773535//22575960//22608085
chr17:17105905-17105906(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr17:17105964-17105965(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr17:17105997-17105998(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr17:17106024-17106025(-) m6A 3'UTR       24284625//24981863//27773535//27371828//22575960//22608085
chr17:17106085-17106086(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085
chr17:17106112-17106113(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085
chr17:17106218-17106219(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085
chr17:17106297-17106298(-) m6A CDS       24284625//24981863//27773535//27371828//22608085
chr17:17106316-17106317(-) m6A CDS       24284625//24981863//27773535//27371828//22608085
chr17:17106351-17106352(-) m6A CDS       24284625//27773535//22608085
chr17:17106387-17106388(-) m6A CDS       24284625//27773535//22608085
chr17:17107720-17107721(-) m6A intron       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1276
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
PLD6
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1276
Interactor2: PLD6

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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