Basic Information:

  VIRBase ID:  

HHID00070790

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:  MIMAT0005930          NCAPG:  NR_073124     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1276	NCAPG
miRBase Accession/Entrez ID	MIMAT0005930	64151
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CAPG//CHCG//NY-MEL-3//YCG1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1276	rs372186220 chr15:85770551    C/T rs759704230 chr15:85770557    A/G rs949716743 chr15:85770550    T/C rs1469123493 chr15:85770565    T/C rs34381260 chr15:85770563    CT/C rs34381260 chr15:85770563    CT/CTT rs750237476 chr15:85770564    T/C rs764239400 chr15:85770562    T/C rs769744052 chr15:85770560    G/A rs775843960 chr15:85770561    C/A rs775843960 chr15:85770561    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NCAPG	chr4:17817152(+) A-I      intronic chr4:17817369(+) A-I      intronic chr4:17817386(+) A-I      intronic chr4:17817421(+) A-I      intronic chr4:17818529(+) A-I      intronic chr4:17821199(+) A-I      intronic chr4:17821222(+) A-I      intronic chr4:17821245(+) A-I      intronic chr4:17821961(+) A-I      intronic chr4:17822032(+) A-I      intronic chr4:17823856(+) A-I      intronic chr4:17823917(+) A-I      intronic chr4:17823979(+) A-I      intronic chr4:17823989(+) A-I      intronic chr4:17822037(+) A-I      intronic chr4:17818681(+) A-I      intronic chr4:17818657(+) A-I      intronic chr4:17822167(+) A-I      intronic chr4:17821030(+) A-I      intronic chr4:17822104(+) A-I      intronic chr4:17822078(+) A-I      intronic chr4:17822114(+) A-I      intronic chr4:17822065(+) A-I      intronic chr4:17822058(+) A-I      intronic chr4:17823223(+) A-I      intronic chr4:17818586(+) A-I      intronic chr4:17822047(+) A-I      intronic chr4:17821088(+) A-I      intronic chr4:17821125(+) A-I      intronic chr4:17821170(+) A-I      intronic chr4:17822039(+) A-I      intronic chr4:17822139(+) A-I      intronic chr4:17821164(+) A-I      intronic chr4:17817247(+) A-I      intronic chr4:17823216(+) A-I      intronic chr4:17817248(+) A-I      intronic chr4:17818625(+) A-I      intronic chr4:17824024(+) A-I      intronic chr4:17823259(+) A-I      intronic chr4:17823865(+) A-I      intronic chr4:17824073(+) A-I      intronic chr4:17821208(+) A-I      intronic chr4:17818503(+) A-I      intronic chr4:17818717(+) A-I      intronic chr4:17823998(+) A-I      intronic chr4:17817408(+) A-I      intronic chr4:17817167(+) A-I      intronic chr4:17823187(+) A-I      intronic chr4:17817277(+) A-I      intronic chr4:17817184(+) A-I      intronic chr4:17818496(+) A-I      intronic chr4:17824075(+) A-I      intronic chr4:17821975(+) A-I      intronic chr4:17821284(+) A-I      intronic chr4:17817212(+) A-I      intronic chr4:17818621(+) A-I      intronic chr4:17818549(+) A-I      intronic chr4:17824004(+) A-I      intronic chr4:17817265(+) A-I      intronic chr4:17817394(+) A-I      intronic chr4:17818686(+) A-I      intronic chr4:17821081(+) A-I      intronic chr4:17818656(+) A-I      intronic chr4:17818555(+) A-I      intronic chr4:17818615(+) A-I      intronic chr4:17823270(+) A-I      intronic chr4:17822041(+) A-I      intronic chr4:17818546(+) A-I      intronic chr4:17821154(+) A-I      intronic chr4:17821129(+) A-I      intronic chr4:17821083(+) A-I      intronic chr4:17821142(+) A-I      intronic chr4:17817409(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NCAPG	chr4:17817184(+) A-I intron -    22327324 chr4:17817212(+) A-I intron -    22327324 chr4:17817277(+) A-I intron -    22327324 chr4:17817394(+) A-I intron -    22327324 chr4:17818625(+) A-I intron -    22327324 chr4:17816176(+) T-C intron -    22484847 chr4:17817167(+) A-G intron -    22484847 chr4:17817179(+) A-G intron -    22484847 chr4:17817184(+) A-G intron -    22484847 chr4:17817212(+) A-G intron -    22484847 chr4:17817247(+) A-G intron -    22484847 chr4:17817248(+) A-G intron -    22484847 chr4:17817265(+) A-G intron -    22484847 chr4:17817277(+) A-G intron -    22484847 chr4:17817287(+) A-G intron -    22484847 chr4:17817289(+) A-G intron -    22484847 chr4:17817335(+) C-T intron -    22484847 chr4:17817374(+) T-C intron -    22484847 chr4:17817376(+) A-G intron -    22484847 chr4:17817399(+) A-G intron -    22484847 chr4:17817408(+) A-G intron -    22484847 chr4:17817409(+) A-G intron -    22484847 chr4:17818546(+) A-G intron -    22484847 chr4:17818555(+) A-G intron -    22484847 chr4:17818615(+) A-G intron -    22484847 chr4:17818621(+) A-G intron -    22484847 chr4:17818625(+) A-G intron -    22484847 chr4:17818686(+) A-G intron -    22484847 chr4:17818717(+) A-G intron -    22484847 chr4:17821081(+) A-G intron -    22484847 chr4:17821083(+) A-G intron -    22484847 chr4:17821129(+) A-G intron -    22484847 chr4:17821142(+) A-G intron -    22484847 chr4:17821154(+) A-G intron -    22484847 chr4:17821284(+) A-G intron -    22484847 chr4:17821975(+) A-G intron -    22484847 chr4:17821983(+) A-G intron -    22484847 chr4:17822041(+) A-G intron -    22484847 chr4:17823145(+) A-G intron -    22484847 chr4:17823166(+) A-G intron -    22484847 chr4:17823216(+) A-G intron -    22484847 chr4:17823259(+) A-G intron -    22484847 chr4:17823287(+) A-G intron -    22484847 chr4:17823865(+) A-G intron -    22484847 chr4:17823998(+) A-G intron -    22484847 chr4:17824004(+) A-G intron -    22484847 chr4:17824024(+) A-G intron -    22484847 chr4:17824074(+) A-G intron -    22484847 chr4:17824075(+) A-G intron -    22484847 chr4:17834753(+) G-A intron -    22484847 chr4:17836890(+) C-T intron -    22484847 chr4:17836982(+) T-C intron -    22484847 chr4:17817154(+) A-G intron -    22484847 chr4:17817156(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NCAPG	chr4:17812611-17812612(+) m6A 5'UTR       24284625//24209618//25456834//24981863 chr4:17812674-17812675(+) m6A 5'UTR//exon       24284625//24209618//24981863//22575960 chr4:17812767-17812768(+) m6A CDS//exon       24209618//22575960 chr4:17813855-17813856(+) m6A CDS//exon       24209618 chr4:17826673-17826674(+) m6A 3'UTR//CDS       27773535 chr4:17827131-17827132(+) m6A 3'UTR//CDS       27773535 chr4:17827145-17827146(+) m6A 3'UTR//CDS       27773535 chr4:17841708-17841709(+) m6A 3'UTR//CDS       27773535 chr4:17842306-17842307(+) m6A 3'UTR//CDS       24981863//27773535 chr4:17843965-17843966(+) m6A 3'UTR//CDS       24981863//27773535 chr4:17843979-17843980(+) m6A 3'UTR//CDS       24981863//27773535 chr4:17844942-17844943(+) m6A 3'UTR//CDS       24981863//27773535 chr4:17844966-17844967(+) m6A 3'UTR//CDS       24981863//27773535 chr4:17844985-17844986(+) m6A 3'UTR//CDS       24981863//27773535 chr4:17845008-17845009(+) m6A 3'UTR//CDS       24981863//27773535 chr4:17845132-17845133(+) m6A 3'UTR       27773535//22608085 chr4:17845326-17845327(+) m6A 3'UTR       24981863//27773535//22608085 chr4:17845360-17845361(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr4:17845436-17845437(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr4:17845447-17845448(+) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr4:17845496-17845497(+) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr4:17845535-17845536(+) m6A 3'UTR       24981863//22608085 chr4:17845572-17845573(+) m6A 3'UTR       24981863//22608085 chr4:17845599-17845600(+) m6A 3'UTR       24981863//22608085 chr4:17845805-17845806(+) m6A 3'UTR       27773535 chr4:17845899-17845900(+) m6A 3'UTR       27773535 chr4:17846289-17846290(+) m6A 3'UTR       27773535 chr4:17846315-17846316(+) m6A 3'UTR       27773535 chr4:17846359-17846360(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1276	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	NCAPG	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Plasma     23663360 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1276
Interactor2: NCAPG

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.