Basic Information:

  VIRBase ID:  

HHID00070788

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:  MIMAT0005930          RIC1:  NM_001135920     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1276	RIC1
miRBase Accession/Entrez ID	MIMAT0005930	57589
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	bA207C16.1//CATIFA//CIP150//KIAA1432

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1276	rs372186220 chr15:85770551    C/T rs759704230 chr15:85770557    A/G rs949716743 chr15:85770550    T/C rs1469123493 chr15:85770565    T/C rs34381260 chr15:85770563    CT/C rs34381260 chr15:85770563    CT/CTT rs750237476 chr15:85770564    T/C rs764239400 chr15:85770562    T/C rs769744052 chr15:85770560    G/A rs775843960 chr15:85770561    C/A rs775843960 chr15:85770561    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RIC1	chr9:5656058(+) A-I      intronic chr9:5655934(+) A-I      intronic chr9:5643038(+) A-I      intronic chr9:5635124(+) A-I      intronic chr9:5635117(+) A-I      intronic chr9:5635091(+) A-I      intronic chr9:5704350(+) A-I      intronic chr9:5768469(+) A-I      intronic chr9:5768448(+) A-I      intronic chr9:5768397(+) A-I      intronic chr9:5768253(+) A-I      intronic chr9:5702704(+) A-I      intronic chr9:5704310(+) A-I      intronic chr9:5704285(+) A-I      intronic chr9:5702808(+) A-I      intronic chr9:5702705(+) A-I      intronic chr9:5701598(+) A-I      intronic chr9:5701516(+) A-I      intronic chr9:5701502(+) A-I      intronic chr9:5701426(+) A-I      intronic chr9:5701364(+) A-I      intronic chr9:5701361(+) A-I      intronic chr9:5701347(+) A-I      intronic chr9:5656077(+) A-I      intronic chr9:5766318(+) A-I      intronic chr9:5766159(+) A-I      intronic chr9:5717698(+) A-I      intronic chr9:5717587(+) A-I      intronic chr9:5716533(+) A-I      intronic chr9:5716466(+) A-I      intronic chr9:5716455(+) A-I      intronic chr9:5716454(+) A-I      intronic chr9:5716451(+) A-I      intronic chr9:5716437(+) A-I      intronic chr9:5716353(+) A-I      intronic chr9:5716079(+) A-I      intronic chr9:5716041(+) A-I      intronic chr9:5716033(+) A-I      intronic chr9:5716031(+) A-I      intronic chr9:5716027(+) A-I      intronic chr9:5716007(+) A-I      intronic chr9:5715986(+) A-I      intronic chr9:5715984(+) A-I      intronic chr9:5715927(+) A-I      intronic chr9:5716002(+) A-I      intronic chr9:5667548(+) A-I      intronic chr9:5702815(+) A-I      intronic chr9:5631533(+) A-I      intronic chr9:5704422(+) A-I      intronic chr9:5716429(+) A-I      intronic chr9:5716534(+) A-I      intronic chr9:5706204(+) A-I      intronic chr9:5704432(+) A-I      intronic chr9:5667118(+) A-I      intronic chr9:5704450(+) A-I      intronic chr9:5768400(+) A-I      intronic chr9:5667733(+) A-I      intronic chr9:5701410(+) A-I      intronic chr9:5717963(+) A-I      intronic chr9:5706205(+) A-I      intronic chr9:5704238(+) A-I      intronic chr9:5715962(+) A-I      intronic chr9:5631500(+) A-I      intronic chr9:5704451(+) A-I      intronic chr9:5716350(+) A-I      intronic chr9:5701397(+) A-I      intronic chr9:5704272(+) A-I      intronic chr9:5704280(+) A-I      intronic chr9:5715922(+) A-I      intronic chr9:5702571(+) A-I      intronic chr9:5701492(+) A-I      intronic chr9:5717590(+) A-I      intronic chr9:5754564(+) A-I      intronic chr9:5717993(+) A-I      intronic chr9:5716017(+) A-I      intronic chr9:5717984(+) A-I      intronic chr9:5716932(+) A-I      intronic chr9:5716034(+) A-I      intronic chr9:5704340(+) A-I      intronic chr9:5702736(+) A-I      intronic chr9:5716072(+) A-I      intronic chr9:5717939(+) A-I      intronic chr9:5701479(+) A-I      intronic chr9:5704447(+) A-I      intronic chr9:5702756(+) A-I      intronic chr9:5716008(+) A-I      intronic chr9:5706313(+) A-I      intronic chr9:5701581(+) A-I      intronic chr9:5715847(+) A-I      intronic chr9:5702781(+) A-I      intronic chr9:5766093(+) A-I      intronic chr9:5704489(+) A-I      intronic chr9:5667224(+) A-I      intronic chr9:5701355(+) A-I      intronic chr9:5704426(+) A-I      intronic chr9:5704236(+) A-I      intronic chr9:5715863(+) A-I      intronic chr9:5701392(+) A-I      intronic chr9:5716044(+) A-I      intronic chr9:5716106(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RIC1	chr9:5763440-5763441(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr9:5763453-5763454(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr9:5763493-5763494(+) m6A CDS//exon       24284625//25456834//24981863//22575960//22608085 chr9:5763542-5763543(+) m6A CDS//exon       24284625//22608085 chr9:5763724-5763725(+) m6A CDS//exon       24284625 chr9:5763748-5763749(+) m6A CDS//exon       24284625 chr9:5763791-5763792(+) m6A CDS//exon       24284625 chr9:5763800-5763801(+) m6A CDS//exon       24284625 chr9:5763836-5763837(+) m6A CDS//exon       24284625 chr9:5768980-5768981(+) m6A CDS//exon       24284625//24981863//22608085 chr9:5768998-5768999(+) m6A 3'UTR//CDS//exon       24284625//24981863//22608085 chr9:5769026-5769027(+) m6A 3'UTR//CDS//exon       24284625//24981863//22608085 chr9:5769064-5769065(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr9:5769098-5769099(+) m6A 3'UTR//CDS//exon       24284625//24981863//22608085 chr9:5769145-5769146(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr9:5769170-5769171(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr9:5769252-5769253(+) m6A 3'UTR//CDS       24284625//24981863 chr9:5769265-5769266(+) m6A CDS//intron       24284625//24981863 chr9:5773031-5773032(+) m6A 3'UTR//CDS       24284625//24209618 chr9:5773039-5773040(+) m6A 3'UTR//CDS       24284625//24209618 chr9:5773058-5773059(+) m6A 3'UTR//CDS       24284625//24209618 chr9:5773076-5773077(+) m6A 3'UTR//CDS       24284625//24209618 chr9:5773980-5773981(+) m6A 3'UTR//CDS       24284625//25456834//24981863//26404942//22608085 chr9:5774012-5774013(+) Gm 3'UTR//CDS       - chr9:5774069-5774070(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr9:5774077-5774078(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr9:5774181-5774182(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr9:5774206-5774207(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr9:5774222-5774223(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22608085 chr9:5774336-5774337(+) m6A 3'UTR       24284625//24981863//22608085 chr9:5774349-5774350(+) m6A 3'UTR       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1276	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	RIC1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1276
Interactor2: RIC1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.