Basic Information:

  VIRBase ID:  

HHID00070787

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:  MIMAT0005930          INTS2:  NM_020748     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1276	INTS2
miRBase Accession/Entrez ID	MIMAT0005930	57508
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	INT2//KIAA1287

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1276	rs372186220 chr15:85770551    C/T rs759704230 chr15:85770557    A/G rs949716743 chr15:85770550    T/C rs1469123493 chr15:85770565    T/C rs34381260 chr15:85770563    CT/C rs34381260 chr15:85770563    CT/CTT rs750237476 chr15:85770564    T/C rs764239400 chr15:85770562    T/C rs769744052 chr15:85770560    G/A rs775843960 chr15:85770561    C/A rs775843960 chr15:85770561    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	INTS2	chr17:59982410(-) A-I      intronic chr17:59982384(-) A-I      intronic chr17:59980205(-) A-I      intronic chr17:59954017(-) A-I      intronic chr17:59965607(-) A-I      intronic chr17:59984083(-) A-I      intronic chr17:59997722(-) A-I      intronic chr17:59997713(-) A-I      intronic chr17:59997710(-) A-I      intronic chr17:59966626(-) A-I      intronic chr17:59988482(-) A-I      intronic chr17:59988481(-) A-I      intronic chr17:59993134(-) A-I      intronic chr17:59987854(-) A-I      intronic chr17:59996395(-) A-I      intronic chr17:59976744(-) A-I      intronic chr17:59975753(-) A-I      intronic chr17:59966712(-) A-I      intronic chr17:59966630(-) A-I      intronic chr17:59966580(-) A-I      intronic chr17:59957070(-) A-I      intronic chr17:59957044(-) A-I      intronic chr17:59957039(-) A-I      intronic chr17:59957038(-) A-I      intronic chr17:59955741(-) A-I      intronic chr17:59953420(-) A-I      intronic chr17:59953338(-) A-I      intronic chr17:59966624(-) A-I      intronic chr17:59957608(-) A-I      intronic chr17:59957612(-) A-I      intronic chr17:59957674(-) A-I      intronic chr17:59958018(-) A-I      intronic chr17:59981639(-) A-I      intronic chr17:59982390(-) A-I      intronic chr17:59982416(-) A-I      intronic chr17:59982777(-) A-I      intronic chr17:59982882(-) A-I      intronic chr17:59983196(-) A-I      intronic chr17:59983251(-) A-I      intronic chr17:59983261(-) A-I      intronic chr17:59983308(-) A-I      intronic chr17:59984087(-) A-I      intronic chr17:59984089(-) A-I      intronic chr17:59984180(-) A-I      intronic chr17:59985596(-) A-I      intronic chr17:59985610(-) A-I      intronic chr17:59985613(-) A-I      intronic chr17:59985654(-) A-I      intronic chr17:59985714(-) A-I      intronic chr17:59986535(-) A-I      intronic chr17:59986665(-) A-I      intronic chr17:59986698(-) A-I      intronic chr17:59987774(-) A-I      intronic chr17:59987789(-) A-I      intronic chr17:59987842(-) A-I      intronic chr17:59962841(-) A-I      intronic chr17:59995780(-) A-I      intronic chr17:59991964(-) A-I      intronic chr17:59991952(-) A-I      intronic chr17:59998418(-) A-I      intronic chr17:59998016(-) A-I      intronic chr17:59998015(-) A-I      intronic chr17:59964781(-) A-I      intronic chr17:59996557(-) A-I      intronic chr17:59996540(-) A-I      intronic chr17:59996382(-) A-I      intronic chr17:59996375(-) A-I      intronic chr17:59963214(-) A-I      intronic chr17:59963227(-) A-I      intronic chr17:59963228(-) A-I      intronic chr17:59963254(-) A-I      intronic chr17:59963484(-) A-I      intronic chr17:59963497(-) A-I      intronic chr17:59963517(-) A-I      intronic chr17:59963590(-) A-I      intronic chr17:59977118(-) A-I      intronic chr17:59976909(-) A-I      intronic chr17:59976903(-) A-I      intronic chr17:59995894(-) A-I      intronic chr17:59995802(-) A-I      intronic chr17:59977191(-) A-I      intronic chr17:59978102(-) A-I      intronic chr17:59978107(-) A-I      intronic chr17:59978545(-) A-I      intronic chr17:59980016(-) A-I      intronic chr17:59980032(-) A-I      intronic chr17:59980179(-) A-I      intronic chr17:59976807(-) A-I      intronic chr17:59980187(-) A-I      intronic chr17:59980192(-) A-I      intronic chr17:59980338(-) A-I      intronic chr17:59980343(-) A-I      intronic chr17:59980444(-) A-I      intronic chr17:59980712(-) A-I      intronic chr17:59981556(-) A-I      intronic chr17:59963615(-) A-I      intronic chr17:59964687(-) A-I      intronic chr17:59964775(-) A-I      intronic chr17:59965202(-) A-I      intronic chr17:59965489(-) A-I      intronic chr17:59966141(-) A-I      intronic chr17:59966120(-) A-I      intronic chr17:59966142(-) A-I      intronic chr17:59966143(-) A-I      intronic chr17:59966173(-) A-I      intronic chr17:59966264(-) A-I      intronic chr17:59966274(-) A-I      intronic chr17:59995782(-) A-I      intronic chr17:59995781(-) A-I      intronic chr17:59995778(-) A-I      intronic chr17:59995767(-) A-I      intronic chr17:59995740(-) A-I      intronic chr17:59988587(-) A-I      intronic chr17:59976792(-) A-I      intronic chr17:59964681(-) A-I      intronic chr17:59953523(-) A-I      intronic chr17:59975952(-) A-I      intronic chr17:59984111(-) A-I      intronic chr17:59982581(-) A-I      intronic chr17:59964800(-) A-I      intronic chr17:60002826(-) A-I      intronic chr17:59963480(-) A-I      intronic chr17:59975787(-) A-I      intronic chr17:59987917(-) A-I      intronic chr17:59986636(-) A-I      intronic chr17:59977223(-) A-I      intronic chr17:59996358(-) A-I      intronic chr17:59985729(-) A-I      intronic chr17:59980676(-) A-I      intronic chr17:59978114(-) A-I      intronic chr17:59983151(-) A-I      intronic chr17:59962864(-) A-I      intronic chr17:59982915(-) A-I      intronic chr17:59963013(-) A-I      intronic chr17:59963479(-) A-I      intronic chr17:59956570(-) A-I      intronic chr17:59980063(-) A-I      intronic chr17:59984242(-) A-I      intronic chr17:59987709(-) A-I      intronic chr17:59982896(-) A-I      intronic chr17:59988595(-) A-I      intronic chr17:59957930(-) A-I      intronic chr17:59982553(-) A-I      intronic chr17:59965157(-) A-I      intronic chr17:59982959(-) A-I      intronic chr17:59957473(-) A-I      intronic chr17:59997904(-) A-I      intronic chr17:59963605(-) A-I      intronic chr17:59964652(-) A-I      intronic chr17:59953446(-) A-I      intronic chr17:59965329(-) A-I      intronic chr17:59977178(-) A-I      intronic chr17:59966129(-) A-I      intronic chr17:59965631(-) A-I      intronic chr17:59978280(-) A-I      intronic chr17:59985676(-) A-I      intronic chr17:59963362(-) A-I      intronic chr17:59953466(-) A-I      intronic chr17:59965514(-) A-I      intronic chr17:59965528(-) A-I      intronic chr17:59965379(-) A-I      intronic chr17:59957844(-) A-I      intronic chr17:59984243(-) A-I      intronic chr17:59997932(-) A-I      intronic chr17:59965337(-) A-I      intronic chr17:59982498(-) A-I      intronic chr17:59962976(-) A-I      intronic chr17:59956499(-) A-I      intronic chr17:59955679(-) A-I      intronic chr17:59988593(-) A-I      intronic chr17:59980426(-) A-I      intronic chr17:59953333(-) A-I      intronic chr17:59964627(-) A-I      intronic chr17:59965609(-) A-I      intronic chr17:59996479(-) A-I      intronic chr17:59963290(-) A-I      intronic chr17:59953968(-) A-I      intronic chr17:59977151(-) A-I      intronic chr17:59965619(-) A-I      intronic chr17:59962977(-) A-I      intronic chr17:59997902(-) A-I      intronic chr17:59963582(-) A-I      intronic chr17:59998243(-) A-I      intronic chr17:60001186(-) A-I      intronic chr17:59978115(-) A-I      intronic chr17:59978548(-) A-I      intronic chr17:59966627(-) A-I      intronic chr17:59979058(-) A-I      intronic chr17:59979116(-) A-I      intronic chr17:59965303(-) A-I      intronic chr17:59991675(-) A-I      intronic chr17:59966585(-) A-I      intronic chr17:59982891(-) A-I      intronic chr17:59963550(-) A-I      intronic chr17:59998042(-) A-I      intronic chr17:59977190(-) A-I      intronic chr17:59975856(-) A-I      intronic chr17:59963004(-) A-I      intronic chr17:59953421(-) A-I      intronic chr17:59991816(-) A-I      intronic chr17:59995731(-) A-I      intronic chr17:59995807(-) A-I      intronic chr17:59954022(-) A-I      intronic chr17:59997639(-) A-I      intronic chr17:59955755(-) A-I      intronic chr17:59963644(-) A-I      intronic chr17:59993539(-) A-I      intronic chr17:59965179(-) A-I      intronic chr17:59981662(-) A-I      intronic chr17:59957679(-) A-I      intronic chr17:59997737(-) A-I      intronic chr17:59975860(-) A-I      intronic chr17:59963639(-) A-I      intronic chr17:59962843(-) A-I      intronic chr17:59976826(-) A-I      intronic chr17:59963540(-) A-I      intronic chr17:59986611(-) A-I      intronic chr17:59998310(-) A-I      intronic chr17:59997736(-) A-I      intronic chr17:59964722(-) A-I      intronic chr17:59976157(-) A-I      intronic chr17:59997793(-) A-I      intronic chr17:59998669(-) A-I      intronic chr17:59964661(-) A-I      intronic chr17:59995806(-) A-I      intronic chr17:59984316(-) A-I      intronic chr17:59977211(-) A-I      intronic chr17:59996563(-) A-I      intronic chr17:59957543(-) A-I      intronic chr17:59981555(-) A-I      intronic chr17:59962872(-) A-I      intronic chr17:59978175(-) A-I      intronic chr17:59975807(-) A-I      intronic chr17:59980108(-) A-I      intronic chr17:59998290(-) A-I      intronic chr17:59965248(-) A-I      intronic chr17:59981580(-) A-I      intronic chr17:59998608(-) A-I      intronic chr17:59957862(-) A-I      intronic chr17:59998008(-) A-I      intronic chr17:59996465(-) A-I      intronic chr17:59976816(-) A-I      intronic chr17:59966531(-) A-I      intronic chr17:59986601(-) A-I      intronic chr17:59991817(-) A-I      intronic chr17:59997205(-) A-I      intronic chr17:59978419(-) A-I      intronic chr17:59997954(-) A-I      intronic chr17:59965404(-) A-I      intronic chr17:59997707(-) A-I      intronic chr17:59982574(-) A-I      intronic chr17:59982405(-) A-I      intronic chr17:59976112(-) A-I      intronic chr17:59982852(-) A-I      intronic chr17:59966323(-) A-I      intronic chr17:59982938(-) A-I      intronic chr17:59986558(-) A-I      intronic chr17:59966514(-) A-I      intronic chr17:59964813(-) A-I      intronic chr17:59998705(-) A-I      intronic chr17:59978127(-) A-I      intronic chr17:59978151(-) A-I      intronic chr17:59965313(-) A-I      intronic chr17:59977125(-) A-I      intronic chr17:59954076(-) A-I      intronic chr17:59964626(-) A-I      intronic chr17:59979057(-) A-I      intronic chr17:60002816(-) A-I      intronic chr17:59985621(-) A-I      intronic chr17:59982900(-) A-I      intronic chr17:59980690(-) A-I      intronic chr17:59995692(-) A-I      intronic chr17:59998345(-) A-I      intronic chr17:59965330(-) A-I      intronic chr17:59982362(-) A-I      intronic chr17:59965265(-) A-I      intronic chr17:59956414(-) A-I      intronic chr17:59964735(-) A-I      intronic chr17:59998653(-) A-I      intronic chr17:59986734(-) A-I      intronic chr17:59953982(-) A-I      intronic chr17:59982690(-) A-I      intronic chr17:59998257(-) A-I      intronic chr17:59963472(-) A-I      intronic chr17:59966608(-) A-I      intronic chr17:59981670(-) A-I      intronic chr17:59981578(-) A-I      intronic chr17:59962941(-) A-I      intronic chr17:59965222(-) A-I      intronic chr17:59978197(-) A-I      intronic chr17:59953295(-) A-I      intronic chr17:59963361(-) A-I      intronic chr17:59966720(-) A-I      intronic chr17:59975929(-) A-I      intronic chr17:59997228(-) A-I      intronic chr17:59966461(-) A-I      intronic chr17:59963284(-) A-I      intronic chr17:59998699(-) A-I      intronic chr17:59975734(-) A-I      intronic chr17:59985509(-) A-I      intronic chr17:59966062(-) A-I      intronic chr17:59964792(-) A-I      intronic chr17:59997648(-) A-I      intronic chr17:59965196(-) A-I      intronic chr17:59992456(-) A-I      intronic chr17:59963504(-) A-I      intronic chr17:59966586(-) A-I      intronic chr17:59983131(-) A-I      intronic chr17:59986654(-) A-I      intronic chr17:59987835(-) A-I      intronic chr17:59957991(-) A-I      intronic chr17:59998081(-) A-I      intronic chr17:59962848(-) A-I      intronic chr17:59966286(-) A-I      intronic chr17:59957088(-) A-I      intronic chr17:59965715(-) A-I      intronic chr17:59980026(-) A-I      intronic chr17:59963024(-) A-I      intronic chr17:59993683(-) A-I      intronic chr17:59965251(-) A-I      intronic chr17:59975875(-) A-I      intronic chr17:59966521(-) A-I      intronic chr17:59965646(-) A-I      intronic chr17:59982962(-) A-I      intronic chr17:59998625(-) A-I      intronic chr17:59997985(-) A-I      intronic chr17:59953447(-) A-I      intronic chr17:59962945(-) A-I      intronic chr17:59964664(-) A-I      intronic chr17:59982472(-) A-I      intronic chr17:59976750(-) A-I      intronic chr17:59976886(-) A-I      intronic chr17:59982785(-) A-I      intronic chr17:59966355(-) A-I      intronic chr17:59966496(-) A-I      intronic chr17:59982745(-) A-I      intronic chr17:59982960(-) A-I      intronic chr17:59953312(-) A-I      intronic chr17:59985664(-) A-I      intronic chr17:59998002(-) A-I      intronic chr17:59953399(-) A-I      intronic chr17:59953364(-) A-I      intronic chr17:59965527(-) A-I      intronic chr17:59987621(-) A-I      intronic chr17:59998214(-) A-I      intronic chr17:59962959(-) A-I      intronic chr17:59971484(-) A-I      intronic chr17:59987103(-) A-I      intronic chr17:59986640(-) A-I      intronic chr17:59977008(-) A-I      intronic chr17:59954041(-) A-I      intronic chr17:59983309(-) A-I      intronic chr17:59964678(-) A-I      intronic chr17:59992990(-) A-I      intronic chr17:59964732(-) A-I      intronic chr17:59954077(-) A-I      intronic chr17:59998305(-) A-I      intronic chr17:59982575(-) A-I      intronic chr17:59985668(-) A-I      intronic chr17:59954007(-) A-I      intronic chr17:59986650(-) A-I      intronic chr17:59985694(-) A-I      intronic chr17:59982430(-) A-I      intronic chr17:59998284(-) A-I      intronic chr17:59976887(-) A-I      intronic chr17:59978382(-) A-I      intronic chr17:59988569(-) A-I      intronic chr17:59965564(-) A-I      intronic chr17:59966317(-) A-I      intronic chr17:59981676(-) A-I      intronic chr17:59965266(-) A-I      intronic chr17:59996459(-) A-I      intronic chr17:59985693(-) A-I      intronic chr17:59963607(-) A-I      intronic chr17:59965994(-) A-I      intronic chr17:59962963(-) A-I      intronic chr17:60002163(-) A-I      intronic chr17:59957093(-) A-I      intronic chr17:59980038(-) A-I      intronic chr17:59984262(-) A-I      intronic chr17:59975876(-) A-I      intronic chr17:59977229(-) A-I      intronic chr17:59963218(-) A-I      intronic chr17:59987791(-) A-I      intronic chr17:59997124(-) A-I      intronic chr17:60001083(-) A-I      intronic chr17:59982780(-) A-I      intronic chr17:59983126(-) A-I      intronic chr17:59948620(-) A-I      intronic chr17:59998266(-) A-I      intronic chr17:59966067(-) A-I      intronic chr17:59986605(-) A-I      intronic chr17:59948597(-) A-I      intronic chr17:59995727(-) A-I      intronic chr17:59965399(-) A-I      intronic chr17:59978379(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	INTS2	chr17:59986601(-) A-I intron -    22327324 chr17:59988593(-) A-I intron -    22327324 chr17:59987103(-) A-G intron -    22484847 chr17:59957093(-) A-G intron -    22484847 chr17:59963480(-) A-G intron -    22484847 chr17:59964626(-) A-G intron -    22484847 chr17:59964735(-) A-G intron -    22484847 chr17:59982362(-) A-G intron -    22484847 chr17:59982575(-) A-G intron -    22484847 chr17:59982581(-) A-G intron -    22484847 chr17:59982959(-) A-G intron -    22484847 chr17:59984242(-) A-G intron -    22484847 chr17:59986601(-) A-G intron -    22484847 chr17:59988593(-) A-G intron -    22484847 chr17:59998266(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	INTS2	chr17:59942751-59942752(-) m6A 3'UTR       27773535 chr17:59942788-59942789(-) m6A 3'UTR       27773535 chr17:59943598-59943599(-) m6A 3'UTR       24209618 chr17:59943754-59943755(-) m6A 3'UTR       27773535 chr17:59944441-59944442(-) m6A 3'UTR       24981863//27773535 chr17:59944599-59944600(-) m6A 3'UTR       27773535 chr17:59944769-59944770(-) m6A 3'UTR       27773535//22608085 chr17:59944800-59944801(-) m6A 3'UTR       24981863//27773535//22608085 chr17:59944830-59944831(-) m6A 3'UTR       24981863//27773535//22608085 chr17:59944841-59944842(-) m6A 3'UTR       24981863//27773535//22608085 chr17:59944903-59944904(-) m6A 3'UTR       24981863//27773535//22608085 chr17:59944915-59944916(-) m6A 3'UTR       24981863//27773535//22608085 chr17:59944958-59944959(-) m6A CDS       24981863//27773535//22608085 chr17:59945008-59945009(-) m6A CDS       24981863//27773535//22608085 chr17:59945064-59945065(-) m6A CDS       24981863//22608085 chr17:59949685-59949686(-) m6A CDS//exon       24981863 chr17:59949732-59949733(-) m6A CDS//exon       24981863 chr17:59984982-59984983(-) m6A CDS       - chr17:59988886-59988887(-) m6A CDS       - chr17:59988903-59988904(-) m6A CDS       - chr17:59988915-59988916(-) m6A CDS       - chr17:59988933-59988934(-) m6A CDS       - chr17:60002325-60002326(-) m6A CDS       24981863 chr17:60002342-60002343(-) m6A CDS       24981863 chr17:60002384-60002385(-) m6A CDS       24981863 chr17:60002402-60002403(-) m6A CDS       24981863 chr17:60002453-60002454(-) m6A CDS       24981863 chr17:60003723-60003724(-) m6A CDS       24981863 chr17:60003741-60003742(-) m6A CDS       24981863 chr17:60003757-60003758(-) m6A CDS       24981863 chr17:60005340-60005341(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1276	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	INTS2	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HCC cell line (HepG2)|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)|K562 cells     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1276
Interactor2: INTS2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.