Basic Information:

  VIRBase ID:  

HHID00070785

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:  MIMAT0005930          NUP107:  NM_001330192     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1276	NUP107
miRBase Accession/Entrez ID	MIMAT0005930	57122
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	GAMOS7//NPHS11//NUP84//ODG6//ODG6

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1276	rs372186220 chr15:85770551    C/T rs759704230 chr15:85770557    A/G rs949716743 chr15:85770550    T/C rs1469123493 chr15:85770565    T/C rs34381260 chr15:85770563    CT/C rs34381260 chr15:85770563    CT/CTT rs750237476 chr15:85770564    T/C rs764239400 chr15:85770562    T/C rs769744052 chr15:85770560    G/A rs775843960 chr15:85770561    C/A rs775843960 chr15:85770561    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NUP107	chr12:69101258(+) A-I      intronic chr12:69101234(+) A-I      intronic chr12:69101199(+) A-I      intronic chr12:69088517(+) A-I      intronic chr12:69086463(+) A-I      intronic chr12:69087233(+) A-I      intronic chr12:69087238(+) A-I      intronic chr12:69085453(+) A-I      intronic chr12:69085483(+) A-I      intronic chr12:69085499(+) A-I      intronic chr12:69085609(+) A-I      intronic chr12:69086120(+) A-I      intronic chr12:69086261(+) A-I      intronic chr12:69104258(+) A-I      intronic chr12:69106188(+) A-I      intronic chr12:69109892(+) A-I      intronic chr12:69112448(+) A-I      intronic chr12:69123761(+) A-I      intronic chr12:69124092(+) A-I      intronic chr12:69124093(+) A-I      intronic chr12:69124165(+) A-I      intronic chr12:69124179(+) A-I      intronic chr12:69132181(+) A-I      intronic chr12:69095283(+) A-I      intronic chr12:69095611(+) A-I      intronic chr12:69095989(+) A-I      intronic chr12:69096265(+) A-I      intronic chr12:69096279(+) A-I      intronic chr12:69101127(+) A-I      intronic chr12:69095262(+) A-I      intronic chr12:69101349(+) A-I      intronic chr12:69101361(+) A-I      intronic chr12:69095252(+) A-I      intronic chr12:69101648(+) A-I      intronic chr12:69095260(+) A-I      intronic chr12:69101700(+) A-I      intronic chr12:69101718(+) A-I      intronic chr12:69101783(+) A-I      intronic chr12:69101859(+) A-I      intronic chr12:69095941(+) A-I      intronic chr12:69104256(+) A-I      intronic chr12:69093757(+) A-I      intronic chr12:69093736(+) A-I      intronic chr12:69089628(+) A-I      intronic chr12:69088432(+) A-I      intronic chr12:69088427(+) A-I      intronic chr12:69087109(+) A-I      intronic chr12:69087057(+) A-I      intronic chr12:69087047(+) A-I      intronic chr12:69087032(+) A-I      intronic chr12:69086631(+) A-I      intronic chr12:69086346(+) A-I      intronic chr12:69102500(+) A-I      intronic chr12:69124273(+) A-I      intronic chr12:69085516(+) A-I      intronic chr12:69130611(+) A-I      intronic chr12:69102579(+) A-I      intronic chr12:69130621(+) A-I      intronic chr12:69102582(+) A-I      intronic chr12:69121879(+) A-I      intronic chr12:69134622(+) A-I      intronic chr12:69098360(+) A-I      intronic chr12:69112530(+) A-I      intronic chr12:69086944(+) A-I      intronic chr12:69089636(+) A-I      intronic chr12:69097311(+) A-I      intronic chr12:69131261(+) A-I      intronic chr12:69101126(+) A-I      intronic chr12:69086623(+) A-I      intronic chr12:69086922(+) A-I      intronic chr12:69093003(+) A-I      intronic chr12:69101780(+) A-I      intronic chr12:69086921(+) A-I      intronic chr12:69101733(+) A-I      intronic chr12:69130425(+) A-I      intronic chr12:69124603(+) A-I      intronic chr12:69095731(+) A-I      intronic chr12:69089666(+) A-I      intronic chr12:69089629(+) A-I      intronic chr12:69087092(+) A-I      intronic chr12:69097774(+) A-I      intronic chr12:69095729(+) A-I      intronic chr12:69092999(+) A-I      intronic chr12:69131745(+) A-I      intronic chr12:69098865(+) A-I      intronic chr12:69086183(+) A-I      intronic chr12:69096037(+) A-I      intronic chr12:69092037(+) A-I      intronic chr12:69101714(+) A-I      intronic chr12:69097717(+) A-I      intronic chr12:69132122(+) A-I      intronic chr12:69086442(+) A-I      intronic chr12:69098711(+) A-I      intronic chr12:69086220(+) A-I      intronic chr12:69089696(+) A-I      intronic chr12:69086271(+) A-I      intronic chr12:69089968(+) A-I      intronic chr12:69101671(+) A-I      intronic chr12:69098763(+) A-I      intronic chr12:69088560(+) A-I      intronic chr12:69086106(+) A-I      intronic chr12:69124099(+) A-I      intronic chr12:69098694(+) A-I      intronic chr12:69088462(+) A-I      intronic chr12:69086239(+) A-I      intronic chr12:69089774(+) A-I      intronic chr12:69124606(+) A-I      intronic chr12:69085463(+) A-I      intronic chr12:69102634(+) A-I      intronic chr12:69088534(+) A-I      intronic chr12:69088467(+) A-I      intronic chr12:69124251(+) A-I      intronic chr12:69102499(+) A-I      intronic chr12:69102504(+) A-I      intronic chr12:69092931(+) A-I      intronic chr12:69122392(+) A-I      intronic chr12:69130296(+) A-I      intronic chr12:69089762(+) A-I      intronic chr12:69086437(+) A-I      intronic chr12:69087182(+) A-I      intronic chr12:69086716(+) A-I      intronic chr12:69122464(+) A-I      intronic chr12:69123871(+) A-I      intronic chr12:69130297(+) A-I      intronic chr12:69124319(+) A-I      intronic chr12:69098351(+) A-I      intronic chr12:69088520(+) A-I      intronic chr12:69098463(+) A-I      intronic chr12:69130339(+) A-I      intronic chr12:69131935(+) A-I      intronic chr12:69086958(+) A-I      intronic chr12:69089567(+) A-I      intronic chr12:69124503(+) A-I      intronic chr12:69122343(+) A-I      intronic chr12:69131316(+) A-I      intronic chr12:69130330(+) A-I      intronic chr12:69089897(+) A-I      intronic chr12:69089618(+) A-I      intronic chr12:69087158(+) A-I      intronic chr12:69095751(+) A-I      intronic chr12:69131262(+) A-I      intronic chr12:69101715(+) A-I      intronic chr12:69112461(+) A-I      intronic chr12:69088426(+) A-I      intronic chr12:69102560(+) A-I      intronic chr12:69086508(+) A-I      intronic chr12:69123755(+) A-I      intronic chr12:69101172(+) A-I      intronic chr12:69123811(+) A-I      intronic chr12:69101667(+) A-I      intronic chr12:69087091(+) A-I      intronic chr12:69098399(+) A-I      intronic chr12:69086248(+) A-I      intronic chr12:69093128(+) A-I      intronic chr12:69090034(+) A-I      intronic chr12:69097756(+) A-I      intronic chr12:69095374(+) A-I      intronic chr12:69109109(+) A-I      intronic chr12:69087131(+) A-I      intronic chr12:69134595(+) A-I      intronic chr12:69089633(+) A-I      intronic chr12:69131744(+) A-I      intronic chr12:69090024(+) A-I      intronic chr12:69123790(+) A-I      intronic chr12:69086659(+) A-I      intronic chr12:69131226(+) A-I      intronic chr12:69090237(+) A-I      intronic chr12:69097793(+) A-I      intronic chr12:69086456(+) A-I      intronic chr12:69131239(+) A-I      intronic chr12:69093026(+) A-I      intronic chr12:69089891(+) A-I      intronic chr12:69097761(+) A-I      intronic chr12:69134716(+) A-I      intronic chr12:69086105(+) A-I      intronic chr12:69092926(+) A-I      intronic chr12:69087229(+) A-I      intronic chr12:69101717(+) A-I      intronic chr12:69124639(+) A-I      intronic chr12:69087041(+) A-I      intronic chr12:69124629(+) A-I      intronic chr12:69086232(+) A-I      intronic chr12:69101791(+) A-I      intronic chr12:69130221(+) A-I      intronic chr12:69086103(+) A-I      intronic chr12:69130407(+) A-I      intronic chr12:69122304(+) A-I      intronic chr12:69083894(+) A-I      intronic chr12:69086713(+) A-I      intronic chr12:69102596(+) A-I      intronic chr12:69086610(+) A-I      intronic chr12:69134733(+) A-I      intronic chr12:69089775(+) A-I      intronic chr12:69097755(+) A-I      intronic chr12:69085493(+) A-I      intronic chr12:69102528(+) A-I      intronic chr12:69087166(+) A-I      intronic chr12:69088661(+) A-I      intronic chr12:69086630(+) A-I      intronic chr12:69102431(+) A-I      intronic chr12:69127849(+) A-I      intronic chr12:69112454(+) A-I      intronic chr12:69130546(+) A-I      intronic chr12:69092917(+) A-I      intronic chr12:69130240(+) A-I      intronic chr12:69098469(+) A-I      intronic chr12:69122321(+) A-I      intronic chr12:69110128(+) A-I      intronic chr12:69087246(+) A-I      intronic chr12:69130432(+) A-I      intronic chr12:69088459(+) A-I      intronic chr12:69086687(+) A-I      intronic chr12:69101796(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NUP107	chr12:69086271(+) A-G intron -    22484847 chr12:69087131(+) A-G intron -    22484847 chr12:69089629(+) A-G intron -    22484847 chr12:69101796(+) A-G intron -    22484847 chr12:69121879(+) A-G intron -    22484847 chr12:69123871(+) A-G intron -    22484847 chr12:69086103(+) A-G intron -    22484847 chr12:69086105(+) A-G intron -    22484847 chr12:69086106(+) A-G intron -    22484847 chr12:69086183(+) A-G intron -    22484847 chr12:69086220(+) A-G intron -    22484847 chr12:69086232(+) A-G intron -    22484847 chr12:69086248(+) A-G intron -    22484847 chr12:69086259(+) T-C intron -    22484847 chr12:69086508(+) A-G intron -    22484847 chr12:69086623(+) A-G intron -    22484847 chr12:69086687(+) A-G intron -    22484847 chr12:69086716(+) A-G intron -    22484847 chr12:69086921(+) A-G intron -    22484847 chr12:69086958(+) A-G intron -    22484847 chr12:69087091(+) A-G intron -    22484847 chr12:69087229(+) A-G intron -    22484847 chr12:69087246(+) A-G intron -    22484847 chr12:69092917(+) A-G intron -    22484847 chr12:69092926(+) A-G intron -    22484847 chr12:69092931(+) A-G intron -    22484847 chr12:69093128(+) A-G intron -    22484847 chr12:69095729(+) A-G intron -    22484847 chr12:69095731(+) A-G intron -    22484847 chr12:69095751(+) A-G intron -    22484847 chr12:69096037(+) A-G intron -    22484847 chr12:69097311(+) A-G intron -    22484847 chr12:69098351(+) A-G intron -    22484847 chr12:69101671(+) A-G intron -    22484847 chr12:69101791(+) A-G intron -    22484847 chr12:69102431(+) A-G intron -    22484847 chr12:69102499(+) A-G intron -    22484847 chr12:69102500(+) A-G intron -    22484847 chr12:69102504(+) A-G intron -    22484847 chr12:69102560(+) A-G intron -    22484847 chr12:69102582(+) A-G intron -    22484847 chr12:69122392(+) A-G intron -    22484847 chr12:69122464(+) A-G intron -    22484847 chr12:69123755(+) A-G intron -    22484847 chr12:69123811(+) A-G intron -    22484847 chr12:69124503(+) A-G intron -    22484847 chr12:69124606(+) A-G intron -    22484847 chr12:69130407(+) A-G intron -    22484847 chr12:69131207(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NUP107	chr12:69080804-69080805(+) m6A 5'UTR//exon       24981863 chr12:69080849-69080850(+) m6A 5'UTR//CDS//exon       24981863 chr12:69099570-69099571(+) m6A intron       24284625 chr12:69099654-69099655(+) m6A intron       24284625 chr12:69099822-69099823(+) m6A intron       22608085 chr12:69099850-69099851(+) m6A intron       22608085 chr12:69099905-69099906(+) m6A intron       22608085 chr12:69099934-69099935(+) m6A intron       22608085 chr12:69099943-69099944(+) m6A intron       22608085 chr12:69100498-69100499(+) m6A intron       22608085 chr12:69100537-69100538(+) m6A intron       22608085 chr12:69100555-69100556(+) m6A intron       22608085 chr12:69128543-69128544(+) m6A 3'UTR//CDS//intron       27773535 chr12:69128591-69128592(+) m6A 3'UTR//CDS//intron       27773535 chr12:69133537-69133538(+) m6A exon//intron       27773535 chr12:69133606-69133607(+) m6A exon//intron       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1276	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	NUP107	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1276
Interactor2: NUP107

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.