Basic Information:

  VIRBase ID:  

HHID00070781

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:  MIMAT0005930          TBC1D13:  NM_001286772     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1276	TBC1D13
miRBase Accession/Entrez ID	MIMAT0005930	54662
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1276	rs372186220 chr15:85770551    C/T rs759704230 chr15:85770557    A/G rs949716743 chr15:85770550    T/C rs1469123493 chr15:85770565    T/C rs34381260 chr15:85770563    CT/C rs34381260 chr15:85770563    CT/CTT rs750237476 chr15:85770564    T/C rs764239400 chr15:85770562    T/C rs769744052 chr15:85770560    G/A rs775843960 chr15:85770561    C/A rs775843960 chr15:85770561    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TBC1D13	chr9:131564216(+) A-I      intronic chr9:131564474(+) A-I      intronic chr9:131564511(+) A-I      intronic chr9:131564571(+) A-I      intronic chr9:131564575(+) A-I      intronic chr9:131564611(+) A-I      intronic chr9:131567470(+) A-I      intronic chr9:131569061(+) A-I      intronic chr9:131569066(+) A-I      intronic chr9:131569069(+) A-I      intronic chr9:131569070(+) A-I      intronic chr9:131569072(+) A-I      intronic chr9:131559015(+) A-I      intronic chr9:131556855(+) A-I      intronic chr9:131556872(+) A-I      intronic chr9:131556894(+) A-I      intronic chr9:131557452(+) A-I      intronic chr9:131557463(+) A-I      intronic chr9:131558506(+) A-I      intronic chr9:131558531(+) A-I      intronic chr9:131558573(+) A-I      intronic chr9:131558585(+) A-I      intronic chr9:131558593(+) A-I      intronic chr9:131558622(+) A-I      intronic chr9:131558629(+) A-I      intronic chr9:131558658(+) A-I      intronic chr9:131558750(+) A-I      intronic chr9:131558751(+) A-I      intronic chr9:131558791(+) A-I      intronic chr9:131558125(+) A-I      intronic chr9:131558792(+) A-I      intronic chr9:131559018(+) A-I      intronic chr9:131559114(+) A-I      intronic chr9:131559121(+) A-I      intronic chr9:131559156(+) A-I      intronic chr9:131564247(+) A-I      intronic chr9:131569507(+) A-I      intronic chr9:131569600(+) A-I      intronic chr9:131569605(+) A-I      intronic chr9:131559202(+) A-I      intronic chr9:131559228(+) A-I      intronic chr9:131563770(+) A-I      intronic chr9:131559826(+) A-I      intronic chr9:131559943(+) A-I      intronic chr9:131559946(+) A-I      intronic chr9:131559961(+) A-I      intronic chr9:131561164(+) A-I      intronic chr9:131562815(+) A-I      intronic chr9:131563231(+) A-I      intronic chr9:131563329(+) A-I      intronic chr9:131563406(+) A-I      intronic chr9:131563703(+) A-I      intronic chr9:131563704(+) A-I      intronic chr9:131559010(+) A-I      intronic chr9:131563747(+) A-I      intronic chr9:131563771(+) A-I      intronic chr9:131563796(+) A-I      intronic chr9:131563803(+) A-I      intronic chr9:131563804(+) A-I      intronic chr9:131559160(+) A-I      intronic chr9:131560487(+) A-I      intronic chr9:131563331(+) A-I      intronic chr9:131560489(+) A-I      intronic chr9:131559210(+) A-I      intronic chr9:131562779(+) A-I      intronic chr9:131556794(+) A-I      intronic chr9:131563179(+) A-I      intronic chr9:131568964(+) A-I      intronic chr9:131567585(+) A-I      intronic chr9:131557467(+) A-I      intronic chr9:131563366(+) A-I      intronic chr9:131569075(+) A-I      intronic chr9:131563435(+) A-I      intronic chr9:131557495(+) A-I      intronic chr9:131565396(+) A-I      intronic chr9:131559053(+) A-I      intronic chr9:131567370(+) A-I      intronic chr9:131558406(+) A-I      intronic chr9:131566949(+) A-I      intronic chr9:131563384(+) A-I      intronic chr9:131569628(+) A-I      intronic chr9:131569172(+) A-I      intronic chr9:131565039(+) A-I      intronic chr9:131561240(+) A-I      intronic chr9:131558504(+) A-I      intronic chr9:131565389(+) A-I      intronic chr9:131559104(+) A-I      intronic chr9:131559127(+) A-I      intronic chr9:131558716(+) A-I      intronic chr9:131559016(+) A-I      intronic chr9:131559054(+) A-I      intronic chr9:131569555(+) A-I      intronic chr9:131567506(+) A-I      intronic chr9:131563332(+) A-I      intronic chr9:131565155(+) A-I      intronic chr9:131558510(+) A-I      intronic chr9:131560482(+) A-I      intronic chr9:131559046(+) A-I      intronic chr9:131559143(+) A-I      intronic chr9:131556818(+) A-I      intronic chr9:131559056(+) A-I      intronic chr9:131559136(+) A-I      intronic chr9:131558441(+) A-I      intronic chr9:131560317(+) A-I      intronic chr9:131561182(+) A-I      intronic chr9:131559055(+) A-I      intronic chr9:131561193(+) A-I      intronic chr9:131563915(+) A-I      intronic chr9:131557028(+) A-I      intronic chr9:131563255(+) A-I      intronic chr9:131562713(+) A-I      intronic chr9:131559068(+) A-I      intronic chr9:131557946(+) A-I      intronic chr9:131567427(+) A-I      intronic chr9:131560542(+) A-I      intronic chr9:131557879(+) A-I      intronic chr9:131567147(+) A-I      intronic chr9:131552703(+) A-I      intronic chr9:131558013(+) A-I      intronic chr9:131558964(+) A-I      intronic chr9:131566926(+) A-I      intronic chr9:131567423(+) A-I      intronic chr9:131557897(+) A-I      intronic chr9:131567496(+) A-I      intronic chr9:131559060(+) A-I      intronic chr9:131558530(+) A-I      intronic chr9:131561266(+) A-I      intronic chr9:131566867(+) A-I      intronic chr9:131562753(+) A-I      intronic chr9:131558398(+) A-I      intronic chr9:131559007(+) A-I      intronic chr9:131567029(+) A-I      intronic chr9:131569429(+) A-I      intronic chr9:131559052(+) A-I      intronic chr9:131562750(+) A-I      intronic chr9:131561267(+) A-I      intronic chr9:131565053(+) A-I      intronic chr9:131562045(+) A-I      intronic chr9:131569505(+) A-I      intronic chr9:131557950(+) A-I      intronic chr9:131559180(+) A-I      intronic chr9:131562807(+) A-I      intronic chr9:131569549(+) A-I      intronic chr9:131557022(+) A-I      intronic chr9:131558460(+) A-I      intronic chr9:131569002(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TBC1D13	chr9:131558482(+) A-G intron -    22484847 chr9:131559054(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TBC1D13	chr9:131550672-131550673(+) m6A CDS//exon       24981863 chr9:131568561-131568562(+) m6A CDS       24284625//24981863 chr9:131570147-131570148(+) m6A CDS       24284625//24981863//22575960//22608085 chr9:131570221-131570222(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131570231-131570232(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131570241-131570242(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131570277-131570278(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131570299-131570300(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131570833-131570834(+) m6A 3'UTR       24209618 chr9:131571856-131571857(+) m6A 3'UTR       24981863 chr9:131571875-131571876(+) m6A 3'UTR       24981863 chr9:131572012-131572013(+) m6A 3'UTR       22608085 chr9:131572077-131572078(+) Am 3'UTR       - chr9:131572091-131572092(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131572108-131572109(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131572169-131572170(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131572232-131572233(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131572241-131572242(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131572253-131572254(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr9:131572301-131572302(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr9:131572396-131572397(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr9:131572429-131572430(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr9:131572447-131572448(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr9:131572541-131572542(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr9:131572561-131572562(+) m6A 3'UTR       24284625//25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1276	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	TBC1D13	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1276
Interactor2: TBC1D13

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.