Basic Information:

  VIRBase ID:  

HHID00070776

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:  MIMAT0005930          TIPARP:  NM_001184717     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1276	TIPARP
miRBase Accession/Entrez ID	MIMAT0005930	25976
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ARTD14//PARP7//pART14

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1276	rs372186220 chr15:85770551    C/T rs759704230 chr15:85770557    A/G rs949716743 chr15:85770550    T/C rs1469123493 chr15:85770565    T/C rs34381260 chr15:85770563    CT/C rs34381260 chr15:85770563    CT/CTT rs750237476 chr15:85770564    T/C rs764239400 chr15:85770562    T/C rs769744052 chr15:85770560    G/A rs775843960 chr15:85770561    C/A rs775843960 chr15:85770561    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TIPARP	chr3:156405939(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TIPARP	chr3:156402489(+) A-G intron -    22484847 chr3:156413228(+) G-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TIPARP	chr3:156392408-156392409(+) m6A 5'UTR//intron       24981863 chr3:156392726-156392727(+) m6A 5'UTR//intron       24284625 chr3:156393551-156393552(+) m6A 5'UTR//intron       - chr3:156395454-156395455(+) m6A 5'UTR       24284625//24981863//22575960//22608085 chr3:156395498-156395499(+) m6A CDS       24284625//24981863//27773535//22575960//22608085 chr3:156395506-156395507(+) m6A CDS       24284625//24981863//27773535//22575960//22608085 chr3:156395517-156395518(+) m6A CDS       24284625//25456834//24981863//27773535//22575960//22608085 chr3:156395569-156395570(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:156395597-156395598(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:156395633-156395634(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:156395639-156395640(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:156395667-156395668(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:156395715-156395716(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156395733-156395734(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156395746-156395747(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156395828-156395829(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156395841-156395842(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156395921-156395922(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:156395966-156395967(+) m6A CDS       24284625//25456834//24981863//27773535//22575960//22608085 chr3:156396021-156396022(+) m6A CDS       24284625//24981863//26404942//27773535//22575960//22608085 chr3:156396060-156396061(+) m6A CDS       24284625//24981863//26404942//27773535//22575960//22608085 chr3:156396087-156396088(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156396123-156396124(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156396168-156396169(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156396219-156396220(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156396302-156396303(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156398959-156398960(+) m6A CDS//intron       24284625//24981863//27773535//22575960//22608085 chr3:156411811-156411812(+) m6A CDS       24284625//24981863//27773535//22575960//22608085 chr3:156411854-156411855(+) m6A CDS       27773535 chr3:156413772-156413773(+) m6A CDS       27773535 chr3:156421304-156421305(+) m6A CDS       24284625//24981863//22608085 chr3:156421318-156421319(+) m6A CDS       24284625//24981863//22608085 chr3:156421346-156421347(+) m6A CDS       24284625//24981863//27773535//22608085 chr3:156421414-156421415(+) m6A CDS       24284625//24981863//27773535//22575960//22608085 chr3:156421463-156421464(+) m6A CDS       24284625//24981863//27773535//22575960//22608085 chr3:156422489-156422490(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr3:156422529-156422530(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr3:156422545-156422546(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr3:156422577-156422578(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156422625-156422626(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr3:156422953-156422954(+) m6A 3'UTR       27773535 chr3:156422992-156422993(+) m6A 3'UTR       27773535 chr3:156423004-156423005(+) m6A 3'UTR       27773535 chr3:156423014-156423015(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1276	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	TIPARP	Chromatin K562 cells     - Exosome Blood     - Insoluble cytoplasm K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1276
Interactor2: TIPARP

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.