Basic Information:

  VIRBase ID:  

HHID00070770

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:  MIMAT0005930          RAB18:  NR_046172     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1276	RAB18
miRBase Accession/Entrez ID	MIMAT0005930	22931
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	RAB18LI1//WARBM3

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1276	rs372186220 chr15:85770551    C/T rs759704230 chr15:85770557    A/G rs949716743 chr15:85770550    T/C rs1469123493 chr15:85770565    T/C rs34381260 chr15:85770563    CT/C rs34381260 chr15:85770563    CT/CTT rs750237476 chr15:85770564    T/C rs764239400 chr15:85770562    T/C rs769744052 chr15:85770560    G/A rs775843960 chr15:85770561    C/A rs775843960 chr15:85770561    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RAB18	chr10:27809694(+) A-I      intronic chr10:27809738(+) A-I      intronic chr10:27809757(+) A-I      intronic chr10:27809719(+) A-I      intronic chr10:27809703(+) A-I      intronic chr10:27809688(+) A-I      intronic chr10:27809695(+) A-I      intronic chr10:27809690(+) A-I      intronic chr10:27804597(+) A-I      intronic chr10:27804569(+) A-I      intronic chr10:27804564(+) A-I      intronic chr10:27803773(+) A-I      intronic chr10:27801477(+) A-I      intronic chr10:27801374(+) A-I      intronic chr10:27801364(+) A-I      intronic chr10:27809613(+) A-I      intronic chr10:27809767(+) A-I      intronic chr10:27809709(+) A-I      intronic chr10:27809834(+) A-I      intronic chr10:27812581(+) A-I      intronic chr10:27809870(+) A-I      intronic chr10:27812789(+) A-I      intronic chr10:27812683(+) A-I      intronic chr10:27812659(+) A-I      intronic chr10:27813121(+) A-I      intronic chr10:27812621(+) A-I      intronic chr10:27809872(+) A-I      intronic chr10:27812914(+) A-I      intronic chr10:27809725(+) A-I      intronic chr10:27804645(+) A-I      intronic chr10:27813044(+) A-I      intronic chr10:27803831(+) A-I      intronic chr10:27822752(+) A-I      Syn:Val->Val chr10:27801497(+) A-I      intronic chr10:27812887(+) A-I      intronic chr10:27796712(+) A-I      intronic chr10:27809778(+) A-I      intronic chr10:27803778(+) A-I      intronic chr10:27803750(+) A-I      intronic chr10:27803929(+) A-I      intronic chr10:27805329(+) A-I      intronic chr10:27809670(+) A-I      intronic chr10:27801481(+) A-I      intronic chr10:27809617(+) A-I      intronic chr10:27801469(+) A-I      intronic chr10:27800979(+) A-I      intronic chr10:27804583(+) A-I      intronic chr10:27801255(+) A-I      intronic chr10:27804620(+) A-I      intronic chr10:27809591(+) A-I      intronic chr10:27804607(+) A-I      intronic chr10:27801509(+) A-I      intronic chr10:27806242(+) A-I      intronic chr10:27801322(+) A-I      intronic chr10:27805327(+) A-I      intronic chr10:27813129(+) A-I      intronic chr10:27801456(+) A-I      intronic chr10:27812565(+) A-I      intronic chr10:27809626(+) A-I      intronic chr10:27807105(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RAB18	chr10:27822752(+) A-I exon CDS    22327324 chr10:27808239(+) A-I intron -    21960545 chr10:27804607(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RAB18	chr10:27793145-27793146(+) m6A 5'UTR       - chr10:27793175-27793176(+) m6A 5'UTR       - chr10:27815776-27815777(+) m6A CDS//exon//intron       27773535 chr10:27815805-27815806(+) m6A CDS//exon//intron       27773535 chr10:27820475-27820476(+) m6A CDS//intron       27773535 chr10:27820482-27820483(+) m6A CDS//intron       27773535 chr10:27822697-27822698(+) m6A CDS//exon//intron       27773535 chr10:27822725-27822726(+) m6A CDS//exon//intron       24981863//27773535 chr10:27822753-27822754(+) m6A CDS//exon//intron       24981863//27773535 chr10:27826818-27826819(+) m6A CDS//exon       24284625//25456834//24981863//27773535//22608085 chr10:27826850-27826851(+) m6A CDS//exon       24284625//25456834//24981863//27773535//22608085 chr10:27826872-27826873(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22608085 chr10:27826880-27826881(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22608085 chr10:27826897-27826898(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22608085 chr10:27826916-27826917(+) m6A CDS//exon       24284625//25456834//24981863//26404942//27773535//22608085 chr10:27826980-27826981(+) m6A 3'UTR//exon       24284625//25456834//24981863//26404942//27773535//22608085 chr10:27827040-27827041(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22608085 chr10:27827063-27827064(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1276	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	RAB18	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1276
Interactor2: RAB18

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.