Basic Information:

  VIRBase ID:  

HHID00070764

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:  MIMAT0005930          OXSR1:  NM_005109     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1276	OXSR1
miRBase Accession/Entrez ID	MIMAT0005930	9943
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	OSR1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1276	rs372186220 chr15:85770551    C/T rs759704230 chr15:85770557    A/G rs949716743 chr15:85770550    T/C rs1469123493 chr15:85770565    T/C rs34381260 chr15:85770563    CT/C rs34381260 chr15:85770563    CT/CTT rs750237476 chr15:85770564    T/C rs764239400 chr15:85770562    T/C rs769744052 chr15:85770560    G/A rs775843960 chr15:85770561    C/A rs775843960 chr15:85770561    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	OXSR1	chr3:38243957(+) A-I      intronic chr3:38212458(+) A-I      intronic chr3:38243974(+) A-I      intronic chr3:38215984(+) A-I      intronic chr3:38242924(+) A-I      intronic chr3:38243103(+) A-I      intronic chr3:38243122(+) A-I      intronic chr3:38243270(+) A-I      intronic chr3:38250733(+) A-I      intronic chr3:38250741(+) A-I      intronic chr3:38243940(+) A-I      intronic chr3:38294444(+) A-I      3'UTR chr3:38216989(+) A-I      intronic chr3:38211675(+) A-I      intronic chr3:38229351(+) A-I      intronic chr3:38243926(+) A-I      intronic chr3:38222911(+) A-I      intronic chr3:38212294(+) A-I      intronic chr3:38273493(+) A-I      intronic chr3:38240835(+) A-I      intronic chr3:38261550(+) A-I      intronic chr3:38208086(+) A-I      intronic chr3:38250810(+) A-I      intronic chr3:38229299(+) A-I      intronic chr3:38240813(+) A-I      intronic chr3:38212296(+) A-I      intronic chr3:38229312(+) A-I      intronic chr3:38215908(+) A-I      intronic chr3:38243988(+) A-I      intronic chr3:38208162(+) A-I      intronic chr3:38219623(+) A-I      intronic chr3:38243257(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	OXSR1	chr3:38244000(+) A-G intron -    22484847 chr3:38261313(+) T-G intron -    22484847 chr3:38261314(+) T-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	OXSR1	chr3:38207059-38207060(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr3:38207114-38207115(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr3:38207145-38207146(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr3:38207345-38207346(+) m6A 5'UTR//intron       24209618//22575960 chr3:38207377-38207378(+) m6A CDS//intron       24209618//22575960 chr3:38207430-38207431(+) Gm CDS//intron       - chr3:38266103-38266104(+) m6A 3'UTR//CDS//exon       27773535 chr3:38271192-38271193(+) m6A 3'UTR//CDS       24981863 chr3:38271879-38271880(+) m6A 3'UTR//CDS       24981863//27773535 chr3:38271980-38271981(+) m6A 3'UTR//intron       24981863//27773535 chr3:38278368-38278369(+) m6A CDS//exon       24981863 chr3:38287612-38287613(+) m6A CDS//exon       24981863 chr3:38287703-38287704(+) m6A CDS//exon       24981863 chr3:38289188-38289189(+) m6A CDS//exon       24981863 chr3:38291471-38291472(+) m6A CDS//exon       24981863 chr3:38294348-38294349(+) m6A CDS       24284625 chr3:38294382-38294383(+) m6A 3'UTR       24284625//24209618 chr3:38294453-38294454(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr3:38294471-38294472(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr3:38294483-38294484(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr3:38294602-38294603(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr3:38294781-38294782(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085 chr3:38294858-38294859(+) Y 3'UTR       26075521 chr3:38294931-38294932(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr3:38295051-38295052(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:38295069-38295070(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:38295098-38295099(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:38295118-38295119(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:38295171-38295172(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr3:38295235-38295236(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:38295326-38295327(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr3:38295428-38295429(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr3:38295464-38295465(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr3:38295976-38295977(+) m6A 3'UTR       24284625//24209618//24981863//27773535 chr3:38296117-38296118(+) m6A 3'UTR       24981863 chr3:38296371-38296372(+) m6A 3'UTR       24284625 chr3:38296459-38296460(+) m6A 3'UTR       24284625//24209618 chr3:38296478-38296479(+) m6A 3'UTR       24284625//24209618 chr3:38296511-38296512(+) m6A 3'UTR       24284625//24209618//24981863 chr3:38296555-38296556(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr3:38296561-38296562(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr3:38296575-38296576(+) m6A 3'UTR       24284625//24209618//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1276	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	OXSR1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1276
Interactor2: OXSR1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.