Detail Information

Basic Information:


  VIRBase ID:  

HHID00070733

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1276:           CCR6:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1276 CCR6
miRBase
Accession/Entrez ID		 MIMAT0005930 1235
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BN-1//C-C CKR-6//CC-CKR-6//CCR-6//CD196//CKR-L3//CKRL3//CMKBR6//DCR2//DRY6//GPR29//GPRCY4//STRL22

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1276
rs372186220 chr15:85770551    C/T
rs759704230 chr15:85770557    A/G
rs949716743 chr15:85770550    T/C
rs1469123493 chr15:85770565    T/C
rs34381260 chr15:85770563    CT/C
rs34381260 chr15:85770563    CT/CTT
rs750237476 chr15:85770564    T/C
rs764239400 chr15:85770562    T/C
rs769744052 chr15:85770560    G/A
rs775843960 chr15:85770561    C/A
rs775843960 chr15:85770561    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CCR6
chr6:167542297(+) A-I      intronic
chr6:167541228(+) A-I      intronic
chr6:167542252(+) A-I      intronic
chr6:167540697(+) A-I      intronic
chr6:167540707(+) A-I      intronic
chr6:167540699(+) A-I      intronic
chr6:167541241(+) A-I      intronic
chr6:167539627(+) A-I      intronic
chr6:167537322(+) A-I      intronic
chr6:167540706(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CCR6
chr6:167537322(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CCR6
chr6:167549574-167549575(+) m6A 5'UTR       -
chr6:167549977-167549978(+) m6A CDS       -
chr6:167549992-167549993(+) m6A CDS       -
chr6:167550142-167550143(+) m6A CDS       -
chr6:167550195-167550196(+) m6A CDS       -
chr6:167550311-167550312(+) m6A CDS       -
chr6:167550324-167550325(+) m6A CDS       -
chr6:167550435-167550436(+) m6A CDS       -
chr6:167550571-167550572(+) m6A CDS       -
chr6:167550612-167550613(+) m6A CDS       -
chr6:167550652-167550653(+) m6A CDS       -
chr6:167550691-167550692(+) m6A CDS       -
chr6:167550715-167550716(+) m6A CDS       -
chr6:167550781-167550782(+) m6A CDS       -
chr6:167550795-167550796(+) m6A CDS       -
chr6:167550804-167550805(+) m6A CDS       -
chr6:167551231-167551232(+) m6A 3'UTR       27773535
chr6:167551237-167551238(+) m6A 3'UTR       27773535
chr6:167551289-167551290(+) m6A 3'UTR       27773535
chr6:167552037-167552038(+) m6A 3'UTR       27773535
chr6:167552071-167552072(+) m6A 3'UTR       27773535
chr6:167552109-167552110(+) m6A 3'UTR       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1276
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
CCR6
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1276
Interactor2: CCR6

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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