Basic Information:

  VIRBase ID:  

HHID00070562

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548o-3p:  MIMAT0005919          TMC7:  NM_001300732     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548o-3p	TMC7
miRBase Accession/Entrez ID	MIMAT0005919	79905
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548o-3p	rs1339101861 chr20:38516618    G/T rs1456728168 chr20:38516617    A/G rs1273591644 chr7:102405749    C/T rs1307755111 chr7:102405760    G/C rs1351519463 chr7:102405754    G/A rs922259473 chr7:102405753    A/G rs1429904758 chr20:38516608    CA/C rs901320936 chr20:38516614    T/C rs1408359821 chr7:102405766    T/C rs1554571744 chr7:102405762    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TMC7	chr16:19072235(+) A-I      intronic chr16:19072254(+) A-I      intronic chr16:19072248(+) A-I      intronic chr16:19042053(+) A-I      intronic chr16:19072226(+) A-I      intronic chr16:19073793(+) A-I      3'UTR chr16:19073828(+) A-I      3'UTR chr16:19072289(+) A-I      intronic chr16:19072266(+) A-I      intronic chr16:19028341(+) A-I      intronic chr16:19042018(+) A-I      intronic chr16:19042040(+) A-I      intronic chr16:19042042(+) A-I      intronic chr16:19042045(+) A-I      intronic chr16:19042046(+) A-I      intronic chr16:19037219(+) A-I      intronic chr16:19040534(+) A-I      intronic chr16:19040538(+) A-I      intronic chr16:19041129(+) A-I      intronic chr16:19011721(+) A-I      intronic chr16:19042938(+) A-I      intronic chr16:19012215(+) A-I      intronic chr16:19024914(+) A-I      intronic chr16:19042872(+) A-I      intronic chr16:19028392(+) A-I      intronic chr16:19025256(+) A-I      intronic chr16:19025269(+) A-I      intronic chr16:19028373(+) A-I      intronic chr16:19028386(+) A-I      intronic chr16:19025280(+) A-I      intronic chr16:19060520(+) A-I      intronic chr16:19036821(+) A-I      intronic chr16:19028387(+) A-I      intronic chr16:19037189(+) A-I      intronic chr16:19011717(+) A-I      intronic chr16:19001758(+) A-I      intronic chr16:18998401(+) A-I      intronic chr16:18998388(+) A-I      intronic chr16:18998207(+) A-I      intronic chr16:19035731(+) A-I      intronic chr16:19035475(+) A-I      intronic chr16:19036820(+) A-I      intronic chr16:19044029(+) A-I      intronic chr16:19060512(+) A-I      intronic chr16:19072654(+) A-I      intronic chr16:19069608(+) A-I      intronic chr16:19065969(+) A-I      intronic chr16:19048819(+) A-I      intronic chr16:19048816(+) A-I      intronic chr16:19045910(+) A-I      intronic chr16:19045671(+) A-I      intronic chr16:19044829(+) A-I      intronic chr16:19044826(+) A-I      intronic chr16:19044821(+) A-I      intronic chr16:19044802(+) A-I      intronic chr16:19044172(+) A-I      intronic chr16:19044024(+) A-I      intronic chr16:19044014(+) A-I      intronic chr16:19074732(+) A-I      3'UTR chr16:19073801(+) A-I      3'UTR chr16:19074641(+) A-I      3'UTR chr16:19073841(+) A-I      3'UTR chr16:19073830(+) A-I      3'UTR chr16:19028236(+) A-I      intronic chr16:19044131(+) A-I      intronic chr16:18999430(+) A-I      intronic chr16:19035596(+) A-I      intronic chr16:19048631(+) A-I      intronic chr16:19061870(+) A-I      intronic chr16:19035031(+) A-I      intronic chr16:19024401(+) A-I      intronic chr16:19044102(+) A-I      intronic chr16:19036001(+) A-I      intronic chr16:19036073(+) A-I      intronic chr16:18998889(+) A-I      intronic chr16:19062265(+) A-I      intronic chr16:18998733(+) A-I      intronic chr16:19035961(+) A-I      intronic chr16:19045799(+) A-I      intronic chr16:19022812(+) A-I      intronic chr16:18999720(+) A-I      intronic chr16:19055005(+) A-I      intronic chr16:19042001(+) A-I      intronic chr16:19024278(+) A-I      intronic chr16:19023927(+) A-I      intronic chr16:19066244(+) A-I      intronic chr16:19037141(+) A-I      intronic chr16:19048931(+) A-I      intronic chr16:19000324(+) A-I      intronic chr16:19048606(+) A-I      intronic chr16:19035658(+) A-I      intronic chr16:19061610(+) A-I      intronic chr16:19048590(+) A-I      intronic chr16:19040935(+) A-I      intronic chr16:19071779(+) A-I      intronic chr16:19042000(+) A-I      intronic chr16:19012162(+) A-I      intronic chr16:19074725(+) A-I      3'UTR chr16:19074834(+) A-I      3'UTR chr16:19074796(+) A-I      3'UTR chr16:19074886(+) A-I      3'UTR chr16:19074755(+) A-I      3'UTR chr16:19074661(+) A-I      3'UTR chr16:19074716(+) A-I      3'UTR chr16:19074754(+) A-I      3'UTR chr16:19023282(+) A-I      intronic chr16:19023317(+) A-I      intronic chr16:19035945(+) A-I      intronic chr16:19055778(+) A-I      intronic chr16:19037156(+) A-I      intronic chr16:19066272(+) A-I      intronic chr16:19012821(+) A-I      intronic chr16:19012858(+) A-I      intronic chr16:19010511(+) A-I      intronic chr16:19001756(+) A-I      intronic chr16:19072292(+) A-I      intronic chr16:19066305(+) A-I      intronic chr16:19035905(+) A-I      intronic chr16:18999432(+) A-I      intronic chr16:19045840(+) A-I      intronic chr16:19072132(+) A-I      intronic chr16:19061572(+) A-I      intronic chr16:18998713(+) A-I      intronic chr16:19028486(+) A-I      intronic chr16:19071789(+) A-I      intronic chr16:19024242(+) A-I      intronic chr16:19061885(+) A-I      intronic chr16:19063392(+) A-I      intronic chr16:19064174(+) A-I      intronic chr16:19069285(+) A-I      intronic chr16:19037157(+) A-I      intronic chr16:19035491(+) A-I      intronic chr16:18998691(+) A-I      intronic chr16:19036876(+) A-I      intronic chr16:19064229(+) A-I      intronic chr16:19024719(+) A-I      intronic chr16:19044872(+) A-I      intronic chr16:19023955(+) A-I      intronic chr16:19062327(+) A-I      intronic chr16:19062008(+) A-I      intronic chr16:19001164(+) A-I      intronic chr16:19021750(+) A-I      intronic chr16:19037298(+) A-I      intronic chr16:19069292(+) A-I      intronic chr16:19068350(+) A-I      intronic chr16:19034181(+) A-I      intronic chr16:19012745(+) A-I      intronic chr16:19023208(+) A-I      intronic chr16:19072188(+) A-I      intronic chr16:18996589(+) A-I      intronic chr16:19037140(+) A-I      intronic chr16:19066860(+) A-I      intronic chr16:19037239(+) A-I      intronic chr16:19023308(+) A-I      intronic chr16:19061952(+) A-I      intronic chr16:19066863(+) A-I      intronic chr16:19044173(+) A-I      intronic chr16:19011579(+) A-I      intronic chr16:19045809(+) A-I      intronic chr16:19044921(+) A-I      intronic chr16:19064215(+) A-I      intronic chr16:19024413(+) A-I      intronic chr16:19071612(+) A-I      intronic chr16:19062097(+) A-I      intronic chr16:19040879(+) A-I      intronic chr16:19044050(+) A-I      intronic chr16:19063425(+) A-I      intronic chr16:19055912(+) A-I      intronic chr16:19065805(+) A-I      intronic chr16:19066854(+) A-I      intronic chr16:18997299(+) A-I      intronic chr16:19044011(+) A-I      intronic chr16:19055321(+) A-I      intronic chr16:19064309(+) A-I      intronic chr16:19070097(+) A-I      intronic chr16:19037225(+) A-I      intronic chr16:19062334(+) A-I      intronic chr16:19061888(+) A-I      intronic chr16:19066332(+) A-I      intronic chr16:19016467(+) A-I      intronic chr16:19044926(+) A-I      intronic chr16:19063879(+) A-I      intronic chr16:19001746(+) A-I      intronic chr16:19066206(+) A-I      intronic chr16:18999632(+) A-I      intronic chr16:19036067(+) A-I      intronic chr16:19035677(+) A-I      intronic chr16:19069623(+) A-I      intronic chr16:19066253(+) A-I      intronic chr16:18999417(+) A-I      intronic chr16:19034254(+) A-I      intronic chr16:19061832(+) A-I      intronic chr16:19049063(+) A-I      intronic chr16:19041940(+) A-I      intronic chr16:19063792(+) A-I      intronic chr16:19063783(+) A-I      intronic chr16:19044054(+) A-I      intronic chr16:19036074(+) A-I      intronic chr16:19063873(+) A-I      intronic chr16:19044030(+) A-I      intronic chr16:19072790(+) A-I      intronic chr16:19032029(+) A-I      intronic chr16:19030273(+) A-I      intronic chr16:18998206(+) A-I      intronic chr16:19071749(+) A-I      intronic chr16:19061696(+) A-I      intronic chr16:19063952(+) A-I      intronic chr16:19001782(+) A-I      intronic chr16:19061634(+) A-I      intronic chr16:19035622(+) A-I      intronic chr16:19062253(+) A-I      intronic chr16:19065783(+) A-I      intronic chr16:19044883(+) A-I      intronic chr16:19048904(+) A-I      intronic chr16:19027172(+) A-I      intronic chr16:19062004(+) A-I      intronic chr16:19028887(+) A-I      intronic chr16:19066017(+) A-I      intronic chr16:19069347(+) A-I      intronic chr16:19008660(+) A-I      intronic chr16:19048921(+) A-I      intronic chr16:19072238(+) A-I      intronic chr16:19037203(+) A-I      intronic chr16:19044849(+) A-I      intronic chr16:19035950(+) A-I      intronic chr16:19035692(+) A-I      intronic chr16:19055790(+) A-I      intronic chr16:19040917(+) A-I      intronic chr16:19038663(+) A-I      intronic chr16:19073735(+) A-I      3'UTR chr16:19073827(+) A-I      3'UTR chr16:19073734(+) A-I      3'UTR chr16:19074665(+) A-I      3'UTR chr16:19074696(+) A-I      3'UTR chr16:19074849(+) A-I      3'UTR chr16:19074795(+) A-I      3'UTR chr16:19074728(+) A-I      3'UTR chr16:19073796(+) A-I      3'UTR chr16:19073873(+) A-I      3'UTR chr16:19074715(+) A-I      3'UTR chr16:19073938(+) A-I      3'UTR chr16:19074697(+) A-I      3'UTR chr16:19074603(+) A-I      3'UTR chr16:19073701(+) A-I      3'UTR chr16:19074790(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TMC7	chr16:19070969(+) A-I intron -    15342557 chr16:19071098(+) A-I intron -    15342557 chr16:19071178(+) A-I intron -    15342557 chr16:19071179(+) A-I intron -    15342557 chr16:19071205(+) A-I intron -    15342557

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TMC7	chr16:19073151-19073152(+) m6A CDS       24981863 chr16:19073160-19073161(+) m6A CDS       24981863 chr16:19073169-19073170(+) m6A 3'UTR       24981863 chr16:19073257-19073258(+) m6A 3'UTR       24981863 chr16:19073365-19073366(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548o-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	TMC7	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548o-3p
Interactor2: TMC7

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.