Detail Information

Basic Information:


  VIRBase ID:  

HHID00070555

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548o-3p:           HNRNPA2B1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548o-3p HNRNPA2B1
miRBase
Accession/Entrez ID		 MIMAT0005919 3181
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HNRNPA2//HNRNPB1//HNRPA2//HNRPA2B1//HNRPB1//IBMPFD2//RNPA2//SNRPB1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548o-3p
rs1339101861 chr20:38516618    G/T
rs1456728168 chr20:38516617    A/G
rs1273591644 chr7:102405749    C/T
rs1307755111 chr7:102405760    G/C
rs1351519463 chr7:102405754    G/A
rs922259473 chr7:102405753    A/G
rs1429904758 chr20:38516608    CA/C
rs901320936 chr20:38516614    T/C
rs1408359821 chr7:102405766    T/C
rs1554571744 chr7:102405762    A/G

RNA Editing:


Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED HNRNPA2B1
chr7:26233778(-) T-C intron -    22484847
chr7:26233875(-) T-C intron -    22484847
chr7:26233941(-) C-T intron -    22484847
chr7:26234740(-) A-T intron -    22484847
chr7:26234741(-) A-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HNRNPA2B1
chr7:26230885-26230886(-) m6A 3'UTR//exon//intron       27773535
chr7:26230908-26230909(-) m6A 3'UTR//exon//intron       27773535
chr7:26231448-26231449(-) m6A 3'UTR//exon//intron       27773535
chr7:26231556-26231557(-) m6A 3'UTR//exon//intron       27773535//22575960
chr7:26231619-26231620(-) m6A 3'UTR//exon//intron       27773535//22575960
chr7:26231729-26231730(-) m6A 3'UTR//exon//intron       26404942//27773535
chr7:26231821-26231822(-) Cm 3'UTR//exon//intron       -
chr7:26231830-26231831(-) m6A 3'UTR//exon//intron       24209618//24981863//28052920//26404942//27773535
chr7:26231875-26231876(-) m6A 3'UTR//exon//intron       24209618//24981863//28052920//26404942//27773535
chr7:26231911-26231912(-) m6A 3'UTR//exon//intron       24209618//24981863//28052920//26404942//27773535
chr7:26231961-26231962(-) m6A exon//intron       24209618//24981863//28052920//26404942//27773535
chr7:26232071-26232072(-) m6A exon//intron       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26232193-26232194(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26232883-26232884(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26232893-26232894(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26232911-26232912(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26233252-26233253(-) m6A CDS//exon       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26235377-26235378(-) m6A exon//intron       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26235473-26235474(-) m6A CDS//exon       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26236048-26236049(-) m6A CDS//exon//intron       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26236054-26236055(-) m6A CDS//exon//intron       24209618//24981863//28052920//26404942//27773535//22575960
chr7:26236219-26236220(-) m6A CDS//exon       24209618//24981863//27773535//22575960
chr7:26236562-26236563(-) m6A CDS//exon       27773535//22575960
chr7:26236625-26236626(-) m6A CDS//exon       27773535
chr7:26236988-26236989(-) m6A CDS//exon       27773535
chr7:26237057-26237058(-) Am CDS//exon       -
chr7:26237248-26237249(-) m6A CDS//exon       26404942//27773535
chr7:26237268-26237269(-) m6A CDS//exon       26404942//27773535//22575960
chr7:26237278-26237279(-) m6A CDS//exon       26404942//27773535//22575960
chr7:26237300-26237301(-) m6A CDS//exon       26404942//27773535//22575960
chr7:26237340-26237341(-) m6A CDS//exon       26404942//27773535//22575960
chr7:26237473-26237474(-) m6A CDS//exon//intron       24981863
chr7:26237482-26237483(-) m6A CDS//exon//intron       24981863
chr7:26237585-26237586(-) m6A exon//intron       24981863
chr7:26239309-26239310(-) m6A exon//intron       -
chr7:26239324-26239325(-) m6A exon//intron       -
chr7:26239405-26239406(-) m6A exon//intron       -
chr7:26240017-26240018(-) m6A exon//intron       24284625//22575960
chr7:26240084-26240085(-) m6A exon//intron       27773535//22575960
chr7:26240218-26240219(-) Gm 5'UTR//exon       -
chr7:26240586-26240587(-) m6A exon       24284625//24981863
chr7:26240616-26240617(-) m6A exon       24284625//24981863
chr7:26240663-26240664(-) m6A exon       24284625//24981863
chr7:26240735-26240736(-) m6A exon       24284625
chr7:26240796-26240797(-) m6A exon       27773535
chr7:26240872-26240873(-) m6A exon       24284625//27773535
chr7:26240936-26240937(-) m6A exon       24284625//24981863
chr7:26240953-26240954(-) m6A exon       24981863
chr7:26240970-26240971(-) m6A exon       24981863
chr7:26241052-26241053(-) m6A exon       24981863
chr7:26241057-26241058(-) m6A exon       24981863
chr7:26241121-26241122(-) m6A exon       25456834//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548o-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
HNRNPA2B1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)|K562 cells     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548o-3p
Interactor2: HNRNPA2B1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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