Detail Information

Basic Information:


  VIRBase ID:  

HHID00070549

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548n:           BEND4:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548n BEND4
miRBase
Accession/Entrez ID		 MIMAT0005916 389206
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CCDC4

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548n
rs1167799411 chr7:34940804    A/G
rs1349024540 chr7:34940825    G/C
rs1440338026 chr7:34940814    C/G
rs1440338026 chr7:34940814    C/T
rs1014154255 chr7:34940819    A/G
rs1170899735 chr7:34940820    C/T
rs541369935 chr7:34940820    CT/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BEND4
chr4:42135763(-) A-I      intronic
chr4:42128007(-) A-I      intronic
chr4:42143642(-) A-I      intronic
chr4:42144059(-) A-I      intronic
chr4:42143994(-) A-I      intronic
chr4:42144069(-) A-I      intronic
chr4:42144053(-) A-I      intronic
chr4:42144563(-) A-I      intronic
chr4:42144570(-) A-I      intronic
chr4:42144538(-) A-I      intronic
chr4:42144195(-) A-I      intronic
chr4:42144567(-) A-I      intronic
chr4:42135760(-) A-I      intronic
chr4:42143974(-) A-I      intronic
chr4:42144528(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED BEND4
chr4:42134659(-) A-G intron -    22484847
chr4:42135760(-) A-G intron -    22484847
chr4:42144195(-) A-G intron -    22484847
chr4:42144528(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BEND4
chr4:42118685-42118686(-) m6A 3'UTR       22608085
chr4:42118690-42118691(-) m6A 3'UTR       22608085
chr4:42118732-42118733(-) m6A 3'UTR       22608085
chr4:42118968-42118969(-) m6A 3'UTR       22608085
chr4:42118987-42118988(-) m6A 3'UTR       22608085
chr4:42118995-42118996(-) m6A 3'UTR       22608085
chr4:42119056-42119057(-) m6A 3'UTR       22608085
chr4:42119082-42119083(-) m6A 3'UTR       22608085
chr4:42119125-42119126(-) m6A 3'UTR       22608085
chr4:42119136-42119137(-) m6A 3'UTR       22608085
chr4:42119156-42119157(-) m6A 3'UTR       22608085
chr4:42119229-42119230(-) m6A 3'UTR       22608085
chr4:42119530-42119531(-) m6A 3'UTR       22608085
chr4:42119635-42119636(-) m6A 3'UTR//CDS       25456834//24981863//27371828//22608085
chr4:42119688-42119689(-) m6A 3'UTR//CDS       25456834//24981863//22608085
chr4:42122121-42122122(-) m6A CDS//intron       25456834//24981863//27371828//22608085
chr4:42122263-42122264(-) m6A CDS       24981863
chr4:42145618-42145619(-) m6A CDS       24981863//22608085
chr4:42145701-42145702(-) m6A CDS       24981863//22608085
chr4:42145774-42145775(-) m6A CDS       24981863//22608085
chr4:42145781-42145782(-) m6A CDS       24981863//22608085
chr4:42145809-42145810(-) m6A CDS       24981863//22608085
chr4:42145818-42145819(-) m6A CDS       24981863//22608085
chr4:42145825-42145826(-) m6A CDS       24981863//22608085
chr4:42145865-42145866(-) m6A CDS       24981863//22608085
chr4:42145929-42145930(-) m6A CDS       24981863//22608085
chr4:42145937-42145938(-) m6A CDS       24981863//22608085
chr4:42154058-42154059(-) m6A CDS//intron       27371828//27773536
chr4:42154178-42154179(-) m6A 5'UTR       27371828//27773536
chr4:42154248-42154249(-) m6A 5'UTR       24981863//27371828//27773536
chr4:42154282-42154283(-) m6A 5'UTR       24981863//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548n
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
BEND4
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548n
Interactor2: BEND4

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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