Basic Information:

  VIRBase ID:  

HHID00070531

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548n:  MIMAT0005916          TBCEL:  NM_001363644     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548n	TBCEL
miRBase Accession/Entrez ID	MIMAT0005916	219899
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	El//LRRC35

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548n	rs1167799411 chr7:34940804    A/G rs1349024540 chr7:34940825    G/C rs1440338026 chr7:34940814    C/G rs1440338026 chr7:34940814    C/T rs1014154255 chr7:34940819    A/G rs1170899735 chr7:34940820    C/T rs541369935 chr7:34940820    CT/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TBCEL	chr11:120940329(+) A-I      intronic chr11:120908808(+) A-I      intronic chr11:120940372(+) A-I      intronic chr11:120898832(+) A-I      intronic chr11:120935635(+) A-I      intronic chr11:120898803(+) A-I      intronic chr11:120908798(+) A-I      intronic chr11:120898793(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TBCEL	chr11:120894829-120894830(+) m6A 5'UTR       24981863 chr11:120894858-120894859(+) m6A 5'UTR       24981863 chr11:120894894-120894895(+) m6A 5'UTR//intron       24981863 chr11:120957495-120957496(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085 chr11:120957539-120957540(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085 chr11:120957546-120957547(+) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085 chr11:120957614-120957615(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr11:120957619-120957620(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr11:120957630-120957631(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr11:120957639-120957640(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr11:120957649-120957650(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr11:120957796-120957797(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085 chr11:120957826-120957827(+) m6A 3'UTR//exon       24284625//24981863//22608085 chr11:120957840-120957841(+) m6A 3'UTR//exon       24284625//24981863//22608085 chr11:120958133-120958134(+) m6A 3'UTR       24981863//22608085 chr11:120958152-120958153(+) m6A 3'UTR       24981863//22608085 chr11:120958191-120958192(+) m6A 3'UTR       24981863//22608085 chr11:120958227-120958228(+) m6A 3'UTR       24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548n	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	TBCEL	Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548n
Interactor2: TBCEL

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.