Basic Information:

  VIRBase ID:  

HHID00070367

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548n:  MIMAT0005916          ENPP4:  NM_014936     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548n	ENPP4
miRBase Accession/Entrez ID	MIMAT0005916	22875
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	NPP4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548n	rs1167799411 chr7:34940804    A/G rs1349024540 chr7:34940825    G/C rs1440338026 chr7:34940814    C/G rs1440338026 chr7:34940814    C/T rs1014154255 chr7:34940819    A/G rs1170899735 chr7:34940820    C/T rs541369935 chr7:34940820    CT/C

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ENPP4	chr6:46107289-46107290(+) m6A 5'UTR       22608085 chr6:46107352-46107353(+) m6A CDS       24981863//22608085 chr6:46107447-46107448(+) m6A CDS       24981863//22608085 chr6:46107527-46107528(+) m6A CDS       24981863//22608085 chr6:46107537-46107538(+) m6A CDS       24981863//22608085 chr6:46107619-46107620(+) m6A CDS       24981863//22608085 chr6:46107702-46107703(+) m6A CDS       24209618//24981863//22608085 chr6:46107808-46107809(+) m6A CDS       24209618//24981863//22608085 chr6:46107834-46107835(+) m6A CDS       24209618//24981863//22608085 chr6:46107843-46107844(+) m6A CDS       24209618//24981863//22608085 chr6:46107880-46107881(+) m6A CDS       24209618//24981863//22608085 chr6:46107907-46107908(+) m6A CDS       24209618//24981863//22608085 chr6:46107924-46107925(+) m6A CDS       24209618//24981863//22608085 chr6:46107979-46107980(+) m6A CDS       24209618//24981863//22608085 chr6:46108056-46108057(+) m6A CDS       24209618//24981863//22608085 chr6:46108068-46108069(+) m6A CDS       24209618//24981863//22608085 chr6:46108793-46108794(+) m6A CDS       24209618//24981863//22608085 chr6:46108810-46108811(+) m6A CDS       24981863//22608085 chr6:46108818-46108819(+) m6A CDS       24981863//22608085 chr6:46108854-46108855(+) m6A CDS       24981863//22608085 chr6:46108928-46108929(+) m6A CDS       24981863//22608085 chr6:46111073-46111074(+) m6A CDS       24209618//24981863//22608085 chr6:46111157-46111158(+) m6A CDS       24981863//22608085 chr6:46111176-46111177(+) m6A CDS       24981863//22608085 chr6:46111307-46111308(+) m6A CDS       24209618//24981863//22608085 chr6:46111420-46111421(+) m6A 3'UTR       24981863//22608085 chr6:46111476-46111477(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548n	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	ENPP4	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548n
Interactor2: ENPP4

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.