Detail Information

Basic Information:


  VIRBase ID:  

HHID00070332

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548n:           WASL:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548n WASL
miRBase
Accession/Entrez ID		 MIMAT0005916 8976
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - N-WASP//NWASP//WASPB

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548n
rs1167799411 chr7:34940804    A/G
rs1349024540 chr7:34940825    G/C
rs1440338026 chr7:34940814    C/G
rs1440338026 chr7:34940814    C/T
rs1014154255 chr7:34940819    A/G
rs1170899735 chr7:34940820    C/T
rs541369935 chr7:34940820    CT/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR WASL
chr7:123361887(-) A-I      intronic
chr7:123361735(-) A-I      intronic
chr7:123360848(-) A-I      intronic
chr7:123360816(-) A-I      intronic
chr7:123360805(-) A-I      intronic
chr7:123360801(-) A-I      intronic
chr7:123360797(-) A-I      intronic
chr7:123348157(-) A-I      intronic
chr7:123348145(-) A-I      intronic
chr7:123340765(-) A-I      intronic
chr7:123340764(-) A-I      intronic
chr7:123340661(-) A-I      intronic
chr7:123340605(-) A-I      intronic
chr7:123340626(-) A-I      intronic
chr7:123361891(-) A-I      intronic
chr7:123380919(-) A-I      intronic
chr7:123360802(-) A-I      intronic
chr7:123339320(-) A-I      intronic
chr7:123328783(-) A-I      intronic
chr7:123328777(-) A-I      intronic
chr7:123366671(-) A-I      intronic
chr7:123361890(-) A-I      intronic
chr7:123328786(-) A-I      intronic
chr7:123340622(-) A-I      intronic
chr7:123356544(-) A-I      intronic
chr7:123356566(-) A-I      intronic
chr7:123340682(-) A-I      intronic
chr7:123340713(-) A-I      intronic
chr7:123340710(-) A-I      intronic
chr7:123353466(-) A-I      intronic
chr7:123380723(-) A-I      intronic
chr7:123340648(-) A-I      intronic
chr7:123361916(-) A-I      intronic
chr7:123339974(-) A-I      intronic
chr7:123340584(-) A-I      intronic
chr7:123361845(-) A-I      intronic
chr7:123358722(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED WASL
chr7:123326803(-) A-I intron -    21960545
chr7:123326805(-) A-I intron -    21960545
chr7:123326806(-) A-I intron -    21960545
chr7:123326826(-) A-I intron -    21960545
chr7:123326879(-) A-I intron -    21960545
chr7:123326887(-) A-I intron -    21960545
chr7:123328353(-) A-I intron -    21960545
chr7:123328375(-) A-I intron -    21960545
chr7:123328776(-) A-I intron -    21960545
chr7:123328791(-) A-I intron -    21960545
chr7:123360852(-) A-I intron -    21960545
chr7:123328581(-) G-A intron -    22484847
chr7:123339974(-) A-G intron -    22484847
chr7:123340648(-) A-G intron -    22484847
chr7:123340710(-) A-G intron -    22484847
chr7:123326879(-) A-G intron -    22484847
chr7:123328757(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase WASL
chr7:123332431-123332432(-) m6A CDS       27773535
chr7:123332473-123332474(-) m6A CDS       27773535
chr7:123332533-123332534(-) m6A CDS       27773535
chr7:123332560-123332561(-) m6A CDS       27773535
chr7:123334781-123334782(-) m6A CDS       24981863//26404942//27773535
chr7:123334810-123334811(-) m6A CDS       24981863//26404942//27773535
chr7:123334843-123334844(-) m6A CDS       24981863//26404942//27773535
chr7:123334851-123334852(-) m6A CDS       24981863//26404942//27773535
chr7:123334857-123334858(-) Y CDS       26075521
chr7:123335909-123335910(-) m6A CDS       24981863//27773535
chr7:123336648-123336649(-) m6A CDS       24981863//27773535
chr7:123388790-123388791(-) m6A 5'UTR       24284625//27773536
chr7:123388811-123388812(-) m6A 5'UTR       24284625//27371828//27773536//22575960
chr7:123389036-123389037(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548n
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
WASL
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548n
Interactor2: WASL

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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